| 09/13/2008
09:38 AM
Detection of protein biomarkers using high-throughput immunoblotting following focal ischemic or penetrating ballistic-like brain injuries in rats
Brain Injury, Volume 22, Issue 10 September 2008 , pages 723 - 732
Recent efforts have been aimed at developing a panel of protein biomarkers for the diagnosis/prognosis of the neurological damage associated with acute brain injury.
09/13/2008
09:34 AM
Medical complications, physical function and communication skills in patients with traumatic brain injury: A single centre 5-year experience
Brain Injury, Volume 22, Issue 10 September 2008 , pages 733 - 739
The aim of this retrospective study was to review the medical complications of patients with traumatic brain injury (TBI) who were followed in 2000-2006.
09/13/2008
09:33 AM
Dysfunctional turning in Parkinson's disease
Disability & Rehabilitation, Volume 30, Issue 16 2008 , pages 1222 - 1229
People with Parkinson's disease (PD) frequently freeze or fall turning: They turn slowly taking numerous steps. We aimed to describe more fully the differences observed on turning between people with and without PD, in particular the extent of left-right asymmetry and the correlations between turning and age, balance and PD severity, using a simple clinical test.
09/13/2008
09:32 AM
Everyday walking with Parkinson's disease: Understanding personal challenges and strategies
Disability & Rehabilitation, Volume 30, Issue 16 2008 , pages 1213 - 1221
This qualitative study was designed to explore the personal experience of everyday walking with Parkinson's disease (PD), the challenges and the strategies employed to compensate for difficulties, to help contextualise the scientific knowledge base.
09/13/2008
09:31 AM
The circumstances of falls among people with Parkinson's disease and the use of Falls Diaries to facilitate reporting
Disability & Rehabilitation, Volume 30, Issue 16 2008 , pages 1205 - 1212
Falls are common in Parkinson's disease (PD). Falls Diaries are one way of recording fall frequency and the surrounding circumstances; completing them encourages recall, and their content focuses intervention. We reviewed the diaries completed by people with PD during a randomized controlled trial (RCT) of fall prevention to ascertain the key circumstances surrounding falls.
09/13/2008
09:29 AM
Impaired mobility and Parkinson's disease
Disability & Rehabilitation, Volume 30, Issue 16 2008 , page 1204
09/13/2008
09:28 AM
Transfemoral amputees' experiences of the first meeting and subsequent interactions with hospital staff
Disability & Rehabilitation, Volume 30, Issue 16 2008 , pages 1192 - 1203
To describe, by use of a phenomenological approach, how transfemoral amputees experience their first meeting and subsequent interaction with hospital staff in the acute phase, in the long term and suggestions for future care-giving.
09/13/2008
09:27 AM
The transition from hospital to home for individuals with acquired brain injury: A literature review and research recommendations
Disability & Rehabilitation, Volume 30, Issue 16 2008 , pages 1153 - 1176
To review the literature relating to the transition from hospital to home for individuals with acquired brain injury (ABI) and make recommendations concerning the future direction of transition-specific research.
09/12/2008
02:53 PM
A Thrombophilic Patient With a Dural Arteriovenous Fistula Presenting Sensory Aphasia and Complicated With an Acute Pulmonary Embolism
Neurologist. 14(5):327-329, September 2008
Neuropsychiatric symptoms as the initial presentation of dural arteriovenous fistula (DAVF) are unusual. Anticoagulation therapy may be warranted for prevention of further thromboembolism if an underlying thrombophilia condition is diagnosed.
09/12/2008
02:52 PM
Surgical outcomes of lateral approach for jugular foramen schwannoma: postoperative facial nerve and lower cranial nerve functions
Neurosurgical Review 0344-5607 (Print) 10.1007/s10143-008-0165-1
The lateral surgical approach to jugular foramen schwannomas (JFS) may result in complications such as temporary facial nerve palsy (FNP) and hearing loss due to the complicated anatomical location.
09/12/2008
02:48 PM
mGluR-dependent persistent firing in entorhinal cortex layer III neurons
European Journal of Neuroscience Volume 28 Issue 6, Pages 1116 - 1126
Persistent firing is believed to be a crucial mechanism for memory function including working memory. Recent in vivo and in vitro findings suggest an involvement of metabotropic glutamate receptors (mGluRs) in persistent firing.
09/12/2008
02:47 PM
Recurrent alcohol-induced seizures in a patient with chronic alcohol abuse
Epileptic Disorders. Volume 10, Number 2, 162-4, June 2008
Seizures related to alcohol are a common finding, and are usually attributed to alcohol withdrawal, or to a neurotoxic effect of ethanol leading to seizures that are unrelated to acute alcohol consumption or withdrawal.
09/12/2008
02:46 PM
Pre-surgical epilepsy evaluation using 3T MRI. Do surface coils provide additional information?
Epileptic Disorders. Volume 10, Number 2, 83-92, June 2008
Purpose. To assess if 3T MRI can be further improved by adding surface coil imaging, in the context of detection and characterization of cerebral lesions in patients with drug-resistant epilepsy.
09/12/2008
02:46 PM
Photosensitivity in epileptic syndromes of childhood and adolescence
Epileptic Disorders. Volume 10, Number 2, 136-43, June 2008
Purpose. Photosensitivity, a reaction of the brain to external photic stimulation, can be graded from 1 to 4, and is most frequently seen in the first decades of life. This study investigated photosensitivity in children with epilepsy.
09/12/2008
02:45 PM
Pediatric extratemporal epilepsy presenting with a complex auditory aura
Epileptic Disorders. Volume 10, Number 2, 181-6, June 2008
Introduction. Ear plugging (placing fingers in or covering the ears) is a clinical seizure semiology that has been described as a response to an unformed, auditory hallucination localized to the superior temporal neocortex.
09/12/2008
02:44 PM
Ocular compression pressure during EEG for the study of increased vagal reactivity
Epileptic Disorders. Volume 10, Number 2, 147-50, June 2008
Ocular compression (OC) is a maneuver performed during EEG to demonstrate increased vagal reactivity in children with suspected syncope including breath-holding spells.
09/12/2008
02:43 PM
Monoamine metabolism study in severe, early-onset epilepsy in childhood
Epileptic Disorders. Volume 10, Number 2, 130-5, June 2008
Purpose. To investigate the possible dysfunction of monoamine metabolism in patients with early-onset, epileptic encephalopathies. Methods. The CSF dopamine, serotonin and biopterin metabolites were studied in 37 patients with severe, mostly drug-resistant epilepsy.
09/12/2008
02:43 PM
Identifying seizure-onset zone and visualizing seizure spread by fMRI: a case report
Epileptic Disorders. Volume 10, Number 2, 93-100, June 2008
Aim. To visualize by ictal, functional MRI, the initial haemodynamic change (i.e. putative seizure-onset zone) and subsequent seizure spread during an epileptic seizure. Methods. A 20-year-old woman was investigated during a simple partial seizure consisting of right-sided mouth clonus.
09/12/2008
02:42 PM
Ictal singing: case report and reappraisal of the literature
Epileptic Disorders. Volume 10, Number 2, 113-8, June 2008
Singing is a rare ictal symptom of focal epilepsy. We report a case of a left-handed woman, with no musical education, experiencing refractory seizures consisting of the singing of a popular Portuguese folksong, with simultaneous, rhythmic hand clapping.
09/12/2008
02:41 PM
Ictal singing due to left mesial temporal sclerosis
Epileptic Disorders. Volume 10, Number 2, 173-6, June 2008
Simple ictal or interictal automatisms are commonly seen in epilepsy, whereas complex automatisms are rare. Simple ictal vocalizations or appendicular automatisms have been reported to be due to mesial temporal lobe epilepsy. However, seizure-associated singing and dancing is very rare.
09/12/2008
02:40 PM
Ictal eructation: a case report
Epileptic Disorders. Volume 10, Number 2, 170-2, June 2008
Gastrointestinal symptoms are considered manifestations of ictal phenomena. Eructations are only rarely described. The present case illustrates eructation as an ictal sign in a patient with symptomatic refractory epilepsy and a left temporal lesion submitted to video-EEG monitoring.
09/12/2008
02:39 PM
Head turning as a prominent motor symptom in status epilepticus
Epileptic Disorders. Volume 10, Number 2, 119-29, June 2008
Head and eye turning is frequently observed during seizures. Versions with tonic and/or clonic symptoms can be differentiated from smooth head deviations. Head turning as a prominent symptom of status epilepticus has not previously been reported.
09/12/2008
02:38 PM
Permissive Hypercapnia and Risk for Brain Injury and Developmental Impairment
PEDIATRICS Vol. 122 No. 3 September 2008, pp. e583-e589
Permissive hypercapnia is a respiratory-care strategy that is used to reduce the risk for lung injury. The goal of this study was to evaluate whether permissive hypercapnia is associated with higher risk for intraventricular hemorrhage and early childhood behavioral and functional problems than normocapnia among very low birth weight infants.
09/12/2008
02:36 PM
Improvements in memory function following anterior temporal lobe resection for epilepsy
Neurology 2008, doi:10.1212/01.wnl.0000319699.04265.fd
While up to a third of patients may experience a decline in memory following an anterior temporal lobe resection (ATL) for epilepsy, between 10 and 20% may experience a postoperative improvement in function. The aim of this study was to examine the preoperative characteristics of these patients.
09/12/2008
02:32 PM
Impaired action knowledge in amyotrophic lateral sclerosis
Neurology 2008, doi:10.1212/01.wnl.0000319701.50168.8c
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative condition affecting the motor system, but recent work also shows more widespread cognitive impairment. This study examined performance on measures requiring knowledge of actions, and related performance to MRI cortical atrophy in ALS.
09/12/2008
02:31 PM
Traumatic brain injury induces the activation of the Nrf2-ARE pathway in the lung in rats
Brain Injury, Volume 22, Issue 10 September 2008 , pages 802 - 810
Acute lung injury (ALI) is a frequent but poorly understood complication of traumatic brain injury (TBI). The Nrf2-ARE pathway has been proved to be essential for protection against diffuse inflammation and oxidative damage, which are both involved in ALI following TBI. However, whether the Nrf2-ARE pathway is activated after TBI in the lung hasn't been studied.
09/12/2008
02:30 PM
Recurrent traumatic brain injury is predicted by the index injury occurring under the influence of alcohol
Brain Injury, Volume 22, Issue 10 September 2008 , pages 780 - 785
Little is known of the role of alcohol intoxication as a risk factor for recurrent traumatic brain injuries (TBI). This study was a population-based longitudinal study to investigate this problem.
09/12/2008
02:29 PM
Prescription medication use in persons many years following traumatic brain injury
Brain Injury, Volume 22, Issue 10 September 2008 , pages 752 - 757
This research study examined the prevalence of prescription medication use in persons many years following moderate-to-severe traumatic brain injury (TBI).
09/12/2008
02:28 PM
Perceived social support and locus of control after a traumatic brain injury (TBI)
Brain Injury, Volume 22, Issue 10 September 2008 , pages 758 - 764
The aim of the study was to investigate the social rehabilitation related to the perceived social support and the locus of control (LC) of patients with traumatic brain injury (TBI).
09/12/2008
02:27 PM
Oral diadochokinesis and velocity of narrative speech: A prognostic parameter for the outcome of diffuse axonal injury in severe head trauma
Brain Injury, Volume 22, Issue 10 September 2008 , pages 773 - 779
Brain Injury, Volume 22, Issue 10 September 2008 , pages 773 - 779
09/12/2008
02:25 PM
Emotional distress and awareness following acquired brain injury: An exploratory analysis
Brain Injury, Volume 22, Issue 10 September 2008 , pages 765 - 772
Symptoms of depression and anxiety are commonly reported following brain injury, providing ongoing challenges to patients, clinicians and carers. There is increasing interest in the influence of impaired awareness on emotional distress, supported by psychological investigations.
09/12/2008
02:25 PM
Changes of cognitive functioning following mild traumatic brain injury over a 3-month period
Brain Injury, Volume 22, Issue 10 September 2008 , pages 740 - 751
To examine the cognitive functioning in patients with complicated mild traumatic brain injury immediately post-injury and at 1 and 3 months post-injury.
09/12/2008
02:23 PM
A standardization study of the Czech version of the Mississippi Aphasia Screening Test (MASTcz) in stroke patients and control subjects
Brain Injury, Volume 22, Issue 10 September 2008 , pages 793 - 801
To assess the criterion and construct validity and inter-rater reliability of the Czech version of the Mississippi Aphasia Screening Test (MASTcz).
09/12/2008
02:21 PM
A French validation study of the Coma Recovery Scale-Revised (CRS-R)
Brain Injury, Volume 22, Issue 10 September 2008 , pages 786 - 792
The aim of the present study was to explore the concurrent validity, inter-rater agreement and diagnostic sensitivity of a French adaptation of the Coma Recovery Scale-Revised (CRS-R) as compared to other coma scales such as the Glasgow Coma Scale (GCS), the Full Outline of UnResponsiveness scale (FOUR) and the Wessex Head Injury Matrix (WHIM).
09/11/2008
03:46 PM
Web-based data management for a phase II clinical trial in ALS
Amyotrophic Lateral Sclerosis First Published on: 09 September 2008
The objective was to report on the creation, features and performance of a web-based data management system for a two-stage phase II randomized clinical trial of Co-Enzyme Q10 in ALS.
09/11/2008
03:46 PM
Triple A syndrome mimicking ALS
Amyotrophic Lateral Sclerosis First Published on: 10 July 2008
We report a 22-year-old female who presented with distal muscular atrophy and weakness in all limbs for two years. Reflexes were symmetrically brisk and electrodiagnostic studies were consistent with upper and lower motor neuron involvement.
09/11/2008
03:45 PM
The syndromes of frontotemporal dysfunction in amyotrophic lateral sclerosis
Amyotrophic Lateral Sclerosis First Published on: 27 August 2008
Amyotrophic lateral sclerosis is increasingly recognized to be a complex multisystems disorder both at the level of its pathobiology and in the breadth of non-motor manifestations that can accompany it.
09/11/2008
03:44 PM
The epidemiology of amyotrophic lateral sclerosis in Reggio Emilia, Italy
Amyotrophic Lateral Sclerosis First Published on: 10 July 2008
ncidence and mortality rates of amyotrophic lateral sclerosis (ALS) vary between countries, and in some studies appear to increase over time. We performed a study to assess ALS incidence in a northern Italy area over a 10-year period.
09/11/2008
03:43 PM
Scrutinizing enrollment in ALS clinical trials: Room for improvement?
Amyotrophic Lateral Sclerosis First Published on: 18 June 2008
Enrollment in ALS trials has not been systematically studied. We surveyed the ALS Research Group (ALSRG) to learn their impressions of enrollment at ALS clinics across North America. We also reviewed completed ALS trials to determine an enrollment rate (subjects per site per month), its variability across trials, whether it is changing over time, and whether it is influenced by 'trial factors'.
09/11/2008
03:42 PM
SOD1 G93D mutation presenting as paucisymptomatic amyotrophic lateral sclerosis
Amyotrophic Lateral Sclerosis First Published on: 31 July 2008
We describe a patient with a familial form of amyotrophic lateral sclerosis (ALS) in which a heterozygous G>A exchange at position 1087 in the SOD1 gene was detected. This mutation results in an amino acid substitution of aspartate for glycine at position 93 (G93D).
09/11/2008
03:41 PM
Quality of life in amyotrophic lateral sclerosis/motor neuron disease: A structured review
Amyotrophic Lateral Sclerosis First Published on: 27 August 2008
Amyotrophic lateral sclerosis/motor neuron disease and other related disorders are fatal progressive neurodegenerative conditions that have a substantial impact on quality of life (QoL). This systematic review examines the different methods and instruments used to assess QoL in this condition from which recommendations are made of those that evidence suggests are the most appropriate.
09/11/2008
03:40 PM
Problem solving skills predict quality of life and psychological morbidity in ALS caregivers
Amyotrophic Lateral Sclerosis First Published on: 11 July 2008
Amyotrophic lateral sclerosis (ALS) often is associated with a particularly intensive caregiving experience, and the well-being of caregivers impacts that of patients. Thus, identification of factors leading to distress in caregivers may provide avenues for intervention that will help both the caregiver and the patient.
09/11/2008
03:39 PM
Phase angle is a prognostic factor for survival in amyotrophic lateral sclerosis
Phase angle is a prognostic factor for survival in amyotrophic lateral sclerosis First Published on: 08 August 2008
Malnutrition is a well-known independent survival factor in ALS patients. Total body impedance analysis (BIA) has been validated for the measurement of fat-free mass.
09/11/2008
03:38 PM
Phase 2 study of sodium phenylbutyrate in ALS
Amyotrophic Lateral Sclerosis First Published on: 07 August 2008
The objective of the study was to establish the safety and pharmacodynamics of escalating dosages of sodium phenylbutyrate (NaPB) in participants with ALS. Transcription dysregulation may play a role in the pathogenesis of ALS.
09/11/2008
03:38 PM
Percutaneous nocturnal oximetry in amyotrophic lateral sclerosis: Periodic desaturation
Amyotrophic Lateral Sclerosis First Published on: 01 September 2008
Percutaneous nocturnal oximetry (PNO) is useful to screen respiratory function in amyotrophic lateral sclerosis (ALS). PNO recordings of some patients disclose a periodical pattern of O2 desaturation (PP), whose significance is unknown.
09/11/2008
03:37 PM
Muscle histopathology in upper motor neuron-dominant amyotrophic lateral sclerosis
Amyotrophic Lateral Sclerosis First Published on: 13 June 2008
The distinction between primary lateral sclerosis (PLS) and amyotrophic lateral sclerosis (ALS) still remains debated. Recently, PLS patients displaying lower motor neuron (LMN) signs have been defined as 'upper motor neuron (UMN)-dominant ALS', using 'clinically pure PLS' diagnosis to those with no LMN signs.
09/11/2008
03:36 PM
Medications and laboratory parameters as prognostic factors in amyotrophic lateral sclerosis
Amyotrophic Lateral Sclerosis First Published on: 12 June 2008
We sought to examine the influence of medication usage and laboratory measurements on disease progression in amyotrophic lateral sclerosis (ALS). A database of 596 volunteers with ALS was generated from three clinical trials and one observational study.
09/11/2008
03:35 PM
Insulin-like growth factor-I for the treatment of amyotrophic lateral sclerosis
Amyotrophic Lateral Sclerosis First Published on: 23 July 2008
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects both upper and lower motor neurons (MN) resulting in weakness, paralysis and subsequent death.
09/11/2008
03:34 PM
Imaging white matter diffusion changes with development and recovery from brain injury
Developmental Neurorehabilitation, Volume 11, Issue 3 2008 , pages 174 - 186
This study reviews the application of diffusion tensor imaging (DTI) to the study of developmental and pathological changes in brain white matter.
09/11/2008
03:33 PM
Factors associated with survival in the National Registry of Veterans with ALS
Amyotrophic Lateral Sclerosis First Published on: 07 August 2008
The clinical course of patients with ALS is highly variable. While the median survival time from symptom onset is 2-4 years, there are reports of survival ranging from less than a year to more than 40 years.
09/11/2008
03:32 PM
Enteral and parenteral nutrition in the later stages of ALS: An observational study
Amyotrophic Lateral Sclerosis First Published on: 10 July 2008
Current practice guidelines state that enteral feeding should be proposed and provided whenever ALS patients show significant dysphagia and/or weight loss. Percutaneous endoscopic gastrostomy (PEG) is usually available at ALS centres, but this method is not indicated in the case of patients with severe respiratory impairment.
09/11/2008
03:31 PM
Development and validation of the Paediatric Care and Needs Scale (PCANS) for assessing support needs of children and youth with acquired brain injury
Developmental Neurorehabilitation, Volume 11, Issue 3 2008 , pages 204 - 214
he Paediatric Care and Needs Scale (PCANS) is a newly developed scale that assesses support needs following childhood acquired brain injury (ABI). It yields three measures of support: overall, extent and intensity. The developmental process of the PCANS is described and concurrent and construct validity examined.
09/11/2008
03:30 PM
Detection of motor cortex thinning and corticospinal tract involvement by quantitative MRI in amyotrophic lateral sclerosis
Amyotrophic Lateral SclerosisFirst Published on: 11 July 2008
We prospectively investigated pathological modifications in the corticospinal tract (CST), by diffusion tensor imaging (DTI) in 14 patients with sporadic amyotrophic lateral sclerosis (ALS) and 12 healthy volunteers.
09/11/2008
03:30 PM
Clinical phenotypes and natural progression for motor neuron disease: Analysis from an Australian database
Amyotrophic Lateral Sclerosis First Published on: 18 June 2008
From 1997 to 2003 we prospectively followed a cohort of ALS/MND patients. Patients were allocated to predetermined clinical phenotypes using the principles established in the modified El Escorial criteria.
09/11/2008
03:29 PM
CSF hypocretin-1 levels are normal in patients with amyotrophic lateral sclerosis
Amyotrophic Lateral Sclerosis First Published on: 07 August 2008
Hypocretin (orexin) neurotransmission is not only crucially involved in the regulation of sleep and wake, but serves in multiple autonomic and cognitive functions as well. This is reflected in the widespread connections between the hypothalamic hypocretin neurons and the rest of the brain, such as dense projections to the frontal cortex.
09/11/2008
03:28 PM
Aggregation of neurodegenerative disease in ALS kindreds
Amyotrophic Lateral Sclerosis First Published on: 18 June 2008
The objective was to investigate the familial occurrence of the neurodegenerative condition amyotrophic lateral sclerosis (ALS), Parkinson's disease and dementia in the relatives of Irish ALS patients.
09/11/2008
03:27 PM
A common haplotype within the PON1 promoter region is associated with sporadic ALS
Amyotrophic Lateral Sclerosis First Published on: 10 July 2008
Amyotrophic lateral sclerosis (ALS) is a progressive, neurodegenerative disorder of upper and lower motor neurons. Genetic variants in the paraoxonase gene cluster have been associated with susceptibility to sporadic ALS.
09/11/2008
03:26 PM
The natural history of the Chiari Type I anomaly
Journal of Neurosurgery: Pediatrics September 2008 Volume 2, Number 3
Since the advent of MR imaging, an increasing number of asymptomatic or oligosymptomatic patients have been diagnosed with Chiari malformation Type I (CM-I).
09/11/2008
03:25 PM
The Dandy-Walker variant: a case series of 24 pediatric patients and evaluation of associated anomalies, incidence of hydrocephalus, and developmental outcomes
Journal of Neurosurgery: Pediatrics September 2008 Volume 2, Number 3
The Dandy-Walker complex is a continuum of aberrant development of the posterior fossa that has been associated with multiple congenital anomalies, radiographic abnormalities, and developmental delay.
09/11/2008
03:23 PM
The use of bone age for bone mineral density interpretation in a cohort of pediatric brain tumor patients
Pediatric Radiology 0301-0449 (Print) 10.1007/s00247-008-0991-x
Skeletal bone accretion occurs throughout childhood. The integrity of this process can influence future adult bone health and the risk of osteoporosis.
09/11/2008
03:22 PM
The role of IL-12 and TNF-{alpha} in AIDP and AMAN
European Journal of Neurology, Volume 15, Number 10, October 2008 , pp. 1100-1105(6)
Acute inflammatory demyelinating polyradiculoneuropathy (AIDP) and acute motor axonal neuropathy (AMAN) have been described as two major subtypes of Guillain-Barre syndrome (GBS); however, the possible difference of their immune-inflammatory pathogenesis remains unclear.
09/11/2008
03:21 PM
To what extent does frontal type executive impairment affect coping strategies in Parkinson's disease?
European Journal of Neurology, Volume 15, Number 10, October 2008 , pp. 1131-1134(4)
Given the frequency of executive dysfunction in Parkinson's disease (PD), we wonder to what extent this fact might influence the coping strategies which are used.
09/11/2008
03:21 PM
Reduced oxygen due to high-altitude exposure relates to atrophy in motor-function brain areas
European Journal of Neurology, Volume 15, Number 10, October 2008 , pp. 1050-1057(8)
At high altitudes barometric pressure is reduced and, thus, less oxygen is inhaled. Reduced oxygen concentration in brain tissue can lead to cerebral damage and neurological and cognitive deficits.
09/11/2008
03:20 PM
Misdiagnosis in epilepsy: a review and recognition of diagnostic uncertainty
European Journal of Neurology, Volume 15, Number 10, October 2008 , pp. 1034-1042(9)
The diagnosis of first seizure or epilepsy may be challenging and misdiagnosis can occur. Studies carried out in various settings have reported misdiagnosis rates of between 4.6% and 30%.
09/11/2008
03:19 PM
Epidemiological study of acute encephalitis in Tottori Prefecture, Japan
European Journal of Neurology, Volume 15, Number 10, October 2008 , pp. 1075-1079(5)
To conduct an epidemiological survey of acute encephalitis focusing on non-herpetic acute limbic encephalitis (NHALE) in Tottori Prefecture, western area of Japan.
09/11/2008
03:18 PM
Diagnostic value of brain MRI and 18F-FDG PET in the differentiation of parkinsonian type multiple system atrophy from Parkinson's disease
European Journal of Neurology, Volume 15, Number 10, October 2008 , pp. 1043-1049(7)
Differentiation between parkinsonian type multiple system atrophy (MSA-P) and Parkinson's disease (PD) is important but often difficult.
09/11/2008
03:17 PM
Clinical heterogeneity and genotype-phenotype correlations in hereditary spastic paraplegia because of Spatacsin mutations (SPG11)
European Journal of Neurology, Volume 15, Number 10, October 2008 , pp. 1065-1070(6)
Autosomal recessive hereditary spastic paraplegia (ARHSP) with thin corpus callosum is a distinct and usually severe form of complex hereditary spastic paraplegia classified as SPG11.
09/11/2008
03:16 PM
Blood pressure is not associated with haematoma enlargement in acute intracerebral haemorrhage
European Journal of Neurology, Volume 15, Number 10, October 2008 , pp. 1085-1090(6)
We performed an observational study that compared baseline and subsequent blood pressure (BP) measurements and its association with haematoma enlargement (HE) in patients with intracerebral haemorrhage (ICH).
09/11/2008
03:14 PM
Interaction Between Warfarin and Panax ginseng in Ischemic Stroke Patients
The Journal of Alternative and Complementary Medicine. July 1, 2008, 14(6): 715-721
Today, the combined use of Oriental herbal medicines and Western biomedical medicines has been a prevalent yet controversial practice.
09/11/2008
03:13 PM
Efficacy and Safety of Acupuncture for Idiopathic Parkinson's Disease: A Systematic Review
The Journal of Alternative and Complementary Medicine. July 1, 2008, 14(6): 663-671
To assess the efficacy and safety of acupuncture therapy (monotherapy or adjuvant therapy), compared with placebo, conventional interventions, or no treatment in treating patients with idiopathic Parkinson's disease (IPD).
09/11/2008
03:12 PM
Reproductive factors and hormone use and risk of adult gliomas
Cancer Causes and Control 0957-5243 (Print) 10.1007/s10552-008-9220-z
Previous research suggests there may be a hormonal influence on glioma risk as evidenced by lower rates in females, change in incidence rates around ages at menarche and menopause, and presence of hormone receptors in glial tumors.
09/11/2008
03:10 PM
Therapeutic strategies for catatonia in paraneoplastic encephalitis
World Journal of Biological Psychiatry, Volume 9, Issue 3 2008 , pages 236 - 240
This report is about a 40-year-old man suffering from fluctuating catatonia as main symptom of long-lasting paraneoplastic encephalitis caused by a testicular neoplasm.
09/11/2008
03:09 PM
Posttraumatic Reactive Fibrous Bone Neoformation of the Anterior Skull Base Mimicking Osteosarcoma
Skull Base : DOI: 10.1055/s-0028-1086058
Malignant bone tumors and fibro-osseous bone lesions of the skull base are uncommon, although fibrous dysplasia in this anatomic location is not a rare condition.
09/11/2008
03:08 PM
Long-Term Outcome of Endonasal Endoscopic Skull Base Reconstruction with Nasal Turbinate Graft
Skull Base : DOI: 10.1055/s-0028-1086055
To study the long-term outcome of endonasal endoscopic skull base reconstruction with nasal turbinate tissue free graft.
09/11/2008
03:07 PM
Procalcitonin N-Terminal Peptide Causes Catabolic Effects via the Hypothalamus and Prostaglandin-Dependent Pathways
Neuroendocrinology (DOI: 10.1159/000155137)
Recent evidence suggests that the free amino-terminal fragment of procalcitonin (N-PCT) plays a role in the central control of feeding behavior and energy homeostasis.
09/11/2008
03:06 PM
Cerebral MRI abnormalities associated with vigabatrin therapy
Epilepsia Published Online: 8 Sep 2008
Investigate whether patients on vigabatrin demonstrated new-onset and reversible T2-weighted magnetic resonance imaging (MRI) abnormalities.
09/11/2008
03:05 PM
Whole-Brain N-Acetylaspartate MR Spectroscopic Quantification: Performance Comparison of Metabolite versus Lipid Nulling
American Journal of Neuroradiology 29:1441-1445, September 2008
Despite the prominent peak of N-acetylaspartate (NAA) in proton MR spectroscopy (1H-MR spectroscopy) of the adult brain and its almost exclusive presence in neuronal cells, the total amount of NAA, regarded as their marker, is difficult to obtain due to signal contamination from the skull lipids.
09/11/2008
03:04 PM
White Matter Changes Contribute to Corpus Callosum Atrophy in the Elderly: The LADIS Study
American Journal of Neuroradiology 29:1498-1504, September 2008
The corpus callosum (CC) is the most important structure involved in the transmission of interhemispheric information.
09/11/2008
03:04 PM
Toward a Uniform Policy for Handling Incidental Findings in Neuroimaging Research
American Journal of Neuroradiology 29:1425-1427, September 2008
A recent study carried out at the University of California, Irvine exemplifies a commonly overlooked ethical conundrum of neuroimaging research: incidental findings.
09/11/2008
03:03 PM
Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis Presenting with Diffusion MR Imaging Changes
American Journal of Neuroradiology 29:1550-1551, September 2008
Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT) presents with focal or diffuse nonenhancing MR imaging abnormalities in 50% of patients with SREAT during subacute exacerbation.
09/11/2008
03:02 PM
Sinonasal Inverted Papilloma: Value of Convoluted Cerebriform Pattern on MR Imaging
American Journal of Neuroradiology 29:1556-1560, September 2008
A convoluted cerebriform pattern (CCP) has been reported as a valuable MR imaging feature of inverted papilloma (IP).
09/11/2008
03:01 PM
Role of Recanalization in Acute Stroke Outcome: Rationale for a CT Angiogram-Based "Benefit of Recanalization" Model
American Journal of Neuroradiology 29:1471-1475, September 2008
In acute middle cerebral artery (MCA) stroke, CT angiographic (CTA) source images (CTA-SI) identify tissue likely to infarct despite early recanalization.
09/11/2008
03:01 PM
Retropharyngeal Lymph Node Metastasis From Esthesioneuroblastoma: A Review of the Therapeutic and Prognostic Implications
American Journal of Neuroradiology 29:1561-1563, September 2008
Esthesioneuroblastoma (ENB) is a malignant neoplasm of the olfactory epithelium.
09/11/2008
03:00 PM
Pseudo-Subarachnoid Hemorrhage Found in Patients with Postresuscitation Encephalopathy: Characteristics of CT Findings and Clinical Importance
American Journal of Neuroradiology 29:1544-1549, September 2008
High-attenuation areas (HDAs) called pseudo-subarachnoid hemorrhages (SAHs) may develop in some patients resuscitated from cardiopulmonary arrest (CPA), though no hemorrhage has occurred.
09/11/2008
02:59 PM
Prognostic Value of Perfusion MR Imaging of High-Grade Astrocytomas: Long-Term Follow-Up Study
American Journal of Neuroradiology 29:1505-1510, September 2008
Although the prognostic value of perfusion MR imaging in various gliomas has been investigated, that in high-grade astrocytomas alone has not been fully evaluated.
09/11/2008
02:58 PM
No Increased Risk for Contrast-Induced Nephropathy after Multiple CT Perfusion Studies of the Brain with a Nonionic, Dimeric, Iso-Osmolal Contrast Medium
American Journal of Neuroradiology 29:1525-1529, September 2008
Contrast-induced nephropathy (CIN) is one of the most common causes of in-hospital acute renal failure.
09/11/2008
02:57 PM
Isolated Cortical Signal Increase on MR Imaging as a Frequent Lesion Pattern in Sporadic Creutzfeldt-Jakob Disease
American Journal of Neuroradiology 29:1519-1524, September 2008
Hyperintense basal ganglia on MR imaging support the diagnosis of sporadic Creutzfeldt-Jakob disease (CJD).
09/11/2008
02:56 PM
In Vivo Differentiation of Aerobic Brain Abscesses and Necrotic Glioblastomas Multiforme Using Proton MR Spectroscopic Imaging
American Journal of Neuroradiology 29:1511-1518, September 2008
Abscesses caused by aerobic bacteria (aerobic abscesses) can simulate intracranial glioblastomas multiforme (GBMs) in MR imaging appearance and single voxel (SV) proton MR spectroscopy of the central cavity.
09/11/2008
02:56 PM
Gene Expression Profiling of Experimental Saccular Aneurysms Using Deoxyribonucleic Acid Microarrays
American Journal of Neuroradiology 29:1566-1569, September 2008
The molecular characteristics of the pathophysiology of saccular aneurysms remain poorly understood.
09/11/2008
02:55 PM
Follow-Up of Coiled Cerebral Aneurysms at 3T: Comparison of 3D Time-of-Flight MR Angiography and Contrast-Enhanced MR Angiography
American Journal of Neuroradiology 29:1530-1536, September 2008
Our aim was to compare contrast-enhanced MR angiography (CE-MRA) and 3D time-of-flight (TOF) MRA at 3T for follow-up of coiled cerebral aneurysms.
09/11/2008
02:54 PM
Flat Panel Detector Angiographic CT in the Management of Aneurysmal Rupture During Coil Embolization
American Journal of Neuroradiology 29:1581-1584, September 2008
Angiographic CT (ACT) produces CT-like images within minutes in the angiography suite.
09/11/2008
02:54 PM
Endovascular Treatment of Intracranial Aneurysms in Patients 65 Years or Older: Clinical Outcomes
American Journal of Neuroradiology 29:1575-1580, September 2008
A controversial discussion concerning treatment of aneurysms in elderly patients exists.
09/11/2008
02:53 PM
Characterization of Aneurysm Remnants after Endovascular Treatment: Contrast-Enhanced MR Angiography versus Catheter Digital Subtraction Angiography
American Journal of Neuroradiology 29:1570-1574, September 2008
A substantial percentage of coiled aneurysms are associated with persistent filling of an aneurysmal component due to incomplete initial treatment or re-growth.
09/11/2008
02:52 PM
Caudate Nucleus Volumes in Frontotemporal Lobar Degeneration: Differential Atrophy in Subtypes
American Journal of Neuroradiology 29:1537-1543, September 2008
Frontostriatal circuits involving the caudate nucleus have been implicated in frontotemporal lobar degeneration (FTLD).
09/11/2008
02:52 PM
Attenuation of Lower-Thoracic, Lumbar, and Sacral Spinal Cord Motion: Implications for Imaging Human Spinal Cord Structure and Function
American Journal of Neuroradiology 29:1450-1454, September 2008
Recent literature indicates that cervical and upper-thoracic spinal cord motion adversely affect both structural and functional MR imaging (fMRI; particularly diffusion tensor imaging [DTI] and spinal fMRI), ultimately reducing the reliability of these methods for both research and clinical applications.
09/11/2008
02:51 PM
Association between Cerebral Microbleeds on T2*-Weighted MR Images and Recurrent Hemorrhagic Stroke in Patients Treated with Warfarin following Ischemic Stroke
American Journal of Neuroradiology 29:1483-1486, September 2008
Although accumulating evidence suggests the presence of microbleeds as a risk factor for intracerebral hemorrhage (ICH), little is known about its significance in anticoagulated patients.
09/11/2008
02:49 PM
Arterial Spin-Labeling in Routine Clinical Practice, Part 3: Hyperperfusion Patterns
American Journal of Neuroradiology 29:1428-1435, September 2008
Arterial spin-labeled (ASL) perfusion imaging can be implemented successfully into a routine clinical neuroimaging protocol and can accurately demonstrate alterations in brain perfusion.
09/11/2008
02:48 PM
Anaplastic meningioma in an adolescent: a report of a rare case and brief review of literature
Child's Nervous System 0256-7040 (Print) 10.1007/s00381-008-0695-4
Anaplastic meningioma is an uncommon neoplasm in childhood and adolescence. Due to the rarity, treatment options for anaplastic meningioma in this age group are not clearly outlined.
09/11/2008
02:40 PM
NEONATAL MENINGOENCEPHALITIS CAUSED BY BACILLUS CEREUS
Pediatric Infectious Disease Journal. 27(9):843-846, September 2008
The classic organisms associated with central nervous system infection in the neonate are herpes simplex, Listeria monocytogenes, Escherichia coli, and Streptococcus agalactiae; we describe an unusual case of neonatal meningoencephalitis caused by Bacillus cereus.
09/11/2008
02:39 PM
Reduced Perception of Dyspnea and Pain After Right Insular Cortex Lesions
Am. J. Respir. Crit. Care Med. 2008, doi:10.1164/rccm.200805-731OC
The perception of dyspnea and pain show many similarities. Initial imaging studies suggested an important role of the insular cortex for the perception of both unpleasant sensations. However, little is still known about the cortical processing of dyspnea.
09/11/2008
02:38 PM
Bartonella sp. Bacteremia in Patients with Neurological and Neurocognitive Dysfunction {triangledown}
Journal of Clinical Microbiology, September 2008, p. 2856-2861, Vol. 46, No. 9
We detected infection with a Bartonella species (B. henselae or B. vinsonii subsp. berkhoffii) in blood samples from six immunocompetent patients who presented with a chronic neurological or neurocognitive syndrome including seizures, ataxia, memory loss, and/or tremors
09/11/2008
02:37 PM
An unexpected EEG course in Dravet syndrome
Epilepsy Research Volume 81, Issue 1, Pages 90-95 (September 2008)
A puzzling EEG pattern combining frontal slow bi-tri spikes followed or not by slow waves when awake and activated by sleep with 5-10s discharges of 8-9Hz spikes in a minority of adolescents with Dravet syndrome (DS) was recorded in the context of stable seizure and cognitive status, and unchanged antiepileptic medication.
09/11/2008
02:35 PM
Hyperhomocysteinemia and retinal vascular changes in patients with epilepsy
Epilepsy Research Volume 81, Issue 1, Pages 86-89 (September 2008)
The possible occurrence of asymptomatic retinal vascular damage was investigated in 87 hyperhomocysteinemic adult epileptic patients.
09/11/2008
02:34 PM
A comparative study of hydrocortisone versus deflazacort in drug-resistant epilepsy of childhood
Epilepsy Research Volume 81, Issue 1, Pages 80-85 (September 2008)
Steroids are commonly used for the treatment of intractable epilepsy. Deflazacort has shown similar effects to prednisone, but with a less worrying adverse-effect profile.
09/11/2008
02:33 PM
Deletion of the SCN gene cluster on 2q24.4 is associated with severe epilepsy: An array-based genotype-phenotype correlation and a comprehensive review of previously published cases
Epilepsy Research Volume 81, Issue 1, Pages 69-79 (September 2008)
To characterize a deletion of chromosome 2q at the molecular level in a patient suffering from severe epilepsy resembling severe myoclonic epilepsy of infancy/Dravet's syndrome (SMEI/DS) and to correlate other cases harboring deletions in the same region to morphological and clinical data.
09/11/2008
02:33 PM
Enhanced EEG functional connectivity in mesial temporal lobe epilepsy
Epilepsy Research Volume 81, Issue 1, Pages 58-68 (September 2008)
To analyze and compare spectral properties and interdependencies of intracerebral EEG signals recorded during interictal periods from mesial temporal lobe structures in two groups of epileptic patients defined according to the involvement of these structures in the epileptogenic zone (EZ).
09/11/2008
02:32 PM
Prenatal stress and epilepsy in later life: A nationwide follow-up study in Denmark
Epilepsy Research Volume 81, Issue 1, Pages 52-57 (September 2008)
To examine whether prenatal exposure to maternal bereavement is associated with an increased risk of epilepsy in the first decades of life.
09/11/2008
02:27 PM
The cannabinoid anticonvulsant effect on pentylenetetrazole-induced seizure is potentiated by ultra-low dose naltrexone in mice
Epilepsy Research Volume 81, Issue 1, Pages 44-51 (September 2008)
Cannabinoid compounds are anticonvulsant since they have inhibitory effects at micromolar doses, which are mediated by activated receptors coupling to Gi/o proteins.
09/11/2008
02:26 PM
The effect of epileptic seizures on proton MRS visible neurochemical concentrations
Epilepsy Research Volume 81, Issue 1, Pages 36-43 (September 2008)
To investigate post-ictal changes in cerebral metabolites.
09/11/2008
02:26 PM
Relationship between post-operative depression/anxiety and hippocampal/amygdala volumes in temporal lobectomy for epilepsy
Epilepsy Research Volume 81, Issue 1, Pages 30-35 (September 2008)
Patients with temporal lobe epilepsy (TLE) often present mood disturbances, which may either exacerbate or remit following surgery. The objective of the study was to investigate the relationship between post-operative depressive/anxiety symptoms and hippocampal/amygdala volumes following anterior temporal lobectomy.
09/11/2008
02:25 PM
Reporting and analysis of open-label extension studies of anti-epileptic drugs
Epilepsy Research Volume 81, Issue 1, Pages 24-29 (September 2008)
Open-label extension studies, or follow-on randomised controlled trials (FORCTs) are widely believed to be prone to patient selection biases which may inflate effect estimates.
09/11/2008
02:24 PM
Activity-dependent induction and maintenance of epileptiform activity produced by group I metabotropic glutamate receptors in the rat hippocampal slice
Epilepsy Research Volume 81, Issue 1, Pages 14-23 (September 2008)
Activation of group I metabotropic glutamate receptors (mGluRs) produces a long-lasting change in hippocampal excitability that persists in the absence of an agonist.
09/11/2008
02:20 PM
Pregnancy outcomes in women with epilepsy: A systematic review and meta-analysis of published pregnancy registries and cohorts
Epilepsy Research Volume 81, Issue 1, Pages 1-13 (September 2008)
To conduct a systematic review and meta-analysis to quantify the incidence of congenital malformations (CMs) and other pregnancy outcomes as a function of in utero anti-epileptic drug (AED) exposure.
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