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American Journal of Neuroradiology 28:511-512, March 2007
We report the development of aseptic meningitis in 3 patients with aneurysms treated with
hydrogel-coated coils. Patients presented with febrile meningeal syndromes during the 24 hours following the procedures and responded to corticosteroids. One of them developed delayed hydrocephalus that required treatment with a ventriculoperitoneal shunt. Aseptic meningitis is one of the important complications related to
hydrogel-coated coils that should be recognized. More information based on the posttreatment surveillance after use of
hydrogel-coated coils is required.
We tested the hypothesis that the HFE genotypes H63D/H63D, H63D/wild type, C282Y/H63D, C282Y/C282Y, and C282Y/wild type are risk factors for symptomatic carotid atherosclerosis, ischemic cerebrovascular disease
(ICVD), and ischemic stroke.
A challenge in the management of severely brain-damaged patients with altered states of consciousness is the differential diagnosis between the vegetative state (VS) and the minimally conscious state (MCS), especially for the gray zone separating these clinical entities.
Journal of Neurotrauma Feb 2007, Vol. 24, No. 2 : 270 -280
We studied the prognostic strength of the individual components of the Glasgow Coma Scale (GCS) and pupil reactivity to Glasgow Outcome Score
(GOS) at 6 months post-injury. A total of 8721 moderate or severe traumatic brain injury
(TBI) patient data from the IMPACT database on traumatic brain injury comprised the study cohort.
To evaluate the arteriovenous malformation (AVM) obliteration rate and the clinical outcome after radiosurgery in patients with and without previous
embolization.
Archives of Psychiatric Nursing Volume 21, Issue 1 , February 2007, Pages 2-11
Measurement of posttraumatic brain injury depression is problematic. Disagreement exists about the best screening measure, and symptoms of brain injury often overlap those of depression.
Clinical Neurology and Neurosurgery Volume 109, Issue 3 , April 2007, Pages 287-291
Acute cranial subdural hematoma (SDH) represents a common consequence of traumatic brain injury. The vast majority of acute SDHs larger than 10 mm in thickness require immediate surgical evacuation. In rare occasions, however, spontaneous resolution may occur.
Journal of Head Trauma Rehabilitation. 22(2):113-121, March/April 2007
To determine whether race/ethnicity and proficiency with the English language influence access to rehabilitation services, and ultimately outcome after traumatic brain injury
(TBI).
Journal of Head Trauma Rehabilitation. 22(2):132-139, March/April 2007
To compare motivation for and participation in rehabilitation, outcome, and distress over role changes in persons with traumatic brain injury
(TBI) from the dominant English-speaking culture in Australia versus those from minority culturally and linguistically diverse
(CALD) backgrounds.
Journal of Head Trauma Rehabilitation. 22(2):122-131, March/April 2007
Compare white and African American caregivers of people with moderate to severe traumatic brain injury
(TBI) regarding caregiving patterns, emotional function and life satisfaction, and preferred supports.
Journal of Head Trauma Rehabilitation. 22(2):95-104, March/April 2007
Racial and ethnic minorities have a disproportionately high rate of disability compared to white Americans, with African and Hispanic Americans overrepresented in all disability categories. Subsequently, the demand for quality employment and rehabilitation services for individuals with disabilities from minority racial or ethnic groups is increasing.
Recurrent cerebrovascular events constitute an estimated 200 000 of the 700 000 strokes reported annually in the United States, which makes secondary stroke prevention an important goal in the management of disease among patients who have experienced stroke or transient ischemic attack.
To retrospectively investigate the association between changes in total cerebral blood flow and progression of total,
periventricular, and deep white matter hyperintensities over time.
Journal of Neurotrauma Feb 2007, Vol. 24, No. 2 : 294 -302
Hypotension following traumatic brain injury (TBI) is recognized as an important secondary insult that is associated with adverse outcome. We aimed to describe the relationship between actual levels of admission blood pressure and Glasgow Outcome Scale
(GOS) at 6 months.
LACS was defined on the basis of neurological signs and did not include imaging. We investigated the interaction between baseline variables and Mg treatment on global outcome.
Morbidity and mortality in spontaneous intracerebral hemorrhage (ICH) are correlated with hematoma progression. We hypothesized that the presence of tiny, enhancing foci ("spot sign") within acute hematomas is associated with hematoma expansion.
Neurosurgery. 60(2) Supplement 1:E173-E174, February 2007
Resection of large intraosseous sphenoid wing meningiomas is traditionally associated with significant morbidity. Rapid prototyping techniques have become widely used for treatment planning. Yet, the transfer of a treatment plan into the intraoperative situs strongly depends on the experience of the individual surgeon.
We obtained brain MRI scans and apoE genotypes in 334 transient ischemic attack or ischemic stroke patients. Microbleeds were scored on a gradient echo MRI and white matter disease was examined on fluid attenuated inversion recovery MRI using a semiquantitative rating scale.
Acta Anaesthesiologica Scandinavica, Volume 51, Number 4, April 2007, pp. 505-508(4)
Maintaining adequate cerebral perfusion pressure is an essential aspect in the treatment of severe acute brain injury. To accomplish this therapeutic goal vasopressors are usually required. Vasopressin is an important endogenous stress hormone and the infusion of low-dose vasopressin and terlipressin has been used to reverse severe hypotension.
Genetic factors influence risk for ischemic stroke and likely do so at multiple steps in the pathogenic process. Variants in genes related to inflammation contribute to risk of stroke. The purpose of this study was to confirm our earlier finding of an association between allele 2 of a variable number tandem repeat of the IL-1 receptor antagonist gene (IL1RN) and cerebrovascular disease.
Clinical Neurology and Neurosurgery Volume 109, Issue 3 , April 2007, Pages 257-262
In this paper a new checklist (CLCE-24) for identification of cognitive and emotional problems after stroke is presented. The CLCE-24 is intended to support a clinical interview by health care professionals other than the trained
(neuro)psychologist.
Clinical Neurology and Neurosurgery Volume 109, Issue 3 , April 2007, Pages 282-286
Spinal subdural hematoma is a rare complication of cranial surgery. This study reports a case of postcraniotomy lumbosacral spinal subdural hematoma in the absence of predisposing factors. A review of the literature is also presented.
Journal of Stroke and Cerebrovascular Diseases Volume 16, Issue 2 , March-April 2007, Pages 71-76
Successful management of acute ischemic stroke is dependent on early referral for
thrombolysis. We explored the key motivational factors affecting stroke sufferers and bystanders and their cognitive and behavioral responses, especially those that would affect prompt management of stroke.
Understanding the long association pathways that convey cortical connections is a critical step in exploring the anatomic substrates of cognition in health and disease. Diffusion tensor imaging (DTI) is able to demonstrate fibre tracts non-invasively, but present approaches have been hampered by the inability to visualize fibres that have intersecting trajectories (crossing
fibres), and by the lack of a detailed map of the origins, course and terminations of the white matter pathways.
Early prognosis of arm recovery is a major clinical issue in stroke. The aim of this study was to assess the prognostic value of 4 simple bedside tests.
American Journal of Neuroradiology 28:524-527, March 2007
Several angiographic features of brain arteriovenous malformations (BAVMs) have been associated with an increased risk of hemorrhage. However, interpretation of these features may not be consistent between observers. We conducted a study to determine inter- and intraobserver agreement of various angioarchitectural characteristics of
BAVM.
Clinical Neurology and Neurosurgery Volume 109, Issue 3 , April 2007, Pages 247-249
The effect of family history of hypertension (FHxHT), as a genetic factor predisposing to some ischemic stroke subtypes and independently of hypertension as risk factor, has never been studied.
Neurosurgery. 60(2) Supplement 1:1-8, February 2007
We investigated the membranous architecture of the abducens nerve at the petroclival region and describe the characteristics of this area in cadaveric specimen and two children with hydrocephalus and sixth nerve palsy using magnetic resonance imaging
(MRI).
Journal of Neurotrauma Feb 2007, Vol. 24, No. 2 : 303 -314
Computerized tomography (CT) scanning provides an objective assessment of the structural damage to the brain following traumatic brain injury
(TBI). We aimed to describe and quantify the relationship between CT characteristics and 6-month outcome, assessed by the Glasgow Outcome Scale
(GOS).
Endovascular coiling has been used increasingly as an alternative to neurosurgical clipping for treating subarachnoid hemorrhage secondary to aneurysm rupture.
Disability and Rehabilitation: Assistive Technology, Volume 2, Issue 2 March 2007 , pages 85 - 95
To examine experiences among individuals in the USA with traumatic brain injury
(TBI) regarding their access to and use of the Internet, problems encountered, and desire for improved Internet access and skills.
Disability and Rehabilitation: Assistive Technology, Volume 2, Issue 2 March 2007 , pages 97 - 103
The purpose of this research was to determine the clinical usefulness of the Tool for Assessing Wheelchair disComfort
(TAWC) by examining floor and ceiling effects and responsiveness when used with two groups of wheelchair users - one known to have experienced real changes in discomfort levels and the other with unchanged levels.
Disability and Rehabilitation: Assistive Technology, Volume 2, Issue 2 March 2007 , pages 71 - 84
Prosthesis use and abandonment is a complex function of variables defining the contextualized individual. This review presents a comprehensive panoramic of these factors as related to the management of upper limb deficiency.
Disability and Rehabilitation: Assistive Technology, Volume 2, Issue 2 March 2007 , pages 117 - 125
This study examined the perspectives of three mothers who used a hoist in the home to assist in the care of a child with a severe physical disability. It sought to identify the effects of hoist introduction on the family as well as factors which influence hoist usage.
Disability and Rehabilitation: Assistive Technology, Volume 2, Issue 2 March 2007 , pages 127 - 132
The purpose of this study was to compare peak functional aerobic power (VO2 peak) across four different types of exercise: arm crank ergometry (ACE), functional electrical stimulation (FES) cycling, and two hybrid exercise conditions: FES cycling combined with ACE and FES rowing using a newly developed rowing device
(ROWSTIM).
Journal of Head Trauma Rehabilitation. 22(1):56-64, January/February 2007
Despite significant advances in the understanding of pediatric traumatic brain injury
(TBI)-related sequelae, members of the medical community working with adult survivors often do not appreciate the impact of "latent" effects of these injuries. To assess deficits and facilitate intervention, the interactions among the nature of the
TBI, the individual's developmental course, and the history of community response must be understood.
Journal of Head Trauma Rehabilitation. 22(1):48-55, January/February 2007
The remarkable persistence of disablement in chronic traumatic brain injury and the dearth of accommodation define the condition as a disorder of adaptation. This construct is extended to explain exceptional recoveries after postacute treatment.
Journal of Head Trauma Rehabilitation. 22(1):1-13, January/February 2007
Assess unmet needs of persons with traumatic brain injury (TBI) 1 year after hospital discharge; compare perceived need with needs based on deficits (unrecognized need); determine major barriers to services; evaluate association of needs with satisfaction with life.
Journal of Head Trauma Rehabilitation. 22(1):26-30, January/February 2007
As clinician ratings of performance-based assessments of activities of daily living
(ADL) require examiners to judge the appropriateness of actions within task context, this study sought to document occupational therapists'
(OTs') ability to distinguish examples of potential ADL errors of healthy adults (HA) from those of individuals with frontal lobe lesions
(FLL).
Journal of Head Trauma Rehabilitation. 22(1):39-47, January/February 2007
Psychotherapy is now an approach used within several models of
neurorehabilitation. However, a core theoretical model to guide psychotherapeutic practice is lacking. This article attempts to illustrate how the Generic Model of Psychotherapy of Orlinsky and Howard, which emphasizes the common factors shared by many psychotherapies, can be applied in neurorehabilitation settings.
A young woman who suffered from urinary retention following a skiing accident. A sacral X-ray (lateral view) revealed an S2–3 sacral fracture. The patient gradually regained the ability to urinate.
To determine natural killer cell cytotoxic activity (NKCA) to 2-h arm ergometer exercise in persons with spinal cord injuries (SCI) and the underlying mechanism of such response.
To evaluate whether the presence of leukoaraiosis or multiple lacunes is associated with symptomatic intracerebral hemorrhage
(ICH) and 90-day outcome after thrombolytic treatment with tissue plasminogen activator
(tPA).
We tested the hypothesis that the HFE genotypes H63D/H63D, H63D/wild type, C282Y/H63D, C282Y/C282Y, and C282Y/wild type are risk factors for symptomatic carotid atherosclerosis, ischemic cerebrovascular disease
(ICVD), and ischemic stroke.
Journal of the International Neuropsychological Society (), 13: 298-311 Cambridge University Press
This study builds on our earlier investigation (see Ganesalingam et al., 2006). We showed previously that children with moderate to severe traumatic brain injuries
(TBI) had poorer self-regulation and social and behavioral functioning than their uninjured peers and that self-regulation predicted significant variance in parent- and teacher-rated social and behavioral outcomes, regardless of the presence or absence of
TBI.
Journal of the International Neuropsychological Society (), 13: 354-358 Cambridge University Press
The performance of 23 patients with moderate to “severe traumatic brain injury on the California Verbal Learning Test, Second Edition
(CVLT-II; Delis et al., 2000) was compared with that of 23 matched healthy controls to determine whether recall discriminability indices, which take into account both correct target recall and intrusive errors, would provide better diagnostic classification than traditional variables that are based exclusively on correct recall.
We report a case of synchronous olfactory bulb meningioma and undifferentiated carcinoma of the nose and paranasal sinuses that involved and destroyed the anterior skull base and mimicked intracranial invasion by a carcinoma.
Individuals with spinal cord injury (SCI) have been reported to have an increased prevalence of premature cardiovascular disease. Whether the increased risk of disease is owing to clustering of traditional cardiac risk factor or is over and above that predicted by risk factors was addressed.
Child's Nervous System, Volume 23, Number 3, March 2007, pp. 355-358(4)
A growing fracture is a rare complication of skull fractures characterized by progressive diastatic enlargement of the fracture line. Growing skull fractures related to birth trauma were only occasionally reported. As far as we know, only one previous case of a neonatal growing fracture secondary to coronal suture disruption has been reported.
Although advances in diffusion tensor imaging have enabled us to better study the anatomy of the inferior longitudinal fasciculus
(ILF), its function remains poorly understood. Recently, it was suggested that the subcortical network subserving the language semantics could be constituted, in parallel with the inferior occipitofrontal fasciculus, by the left
ILF, joining the posterior occipitotemporal regions to the temporal pole, then relayed by the uncinate fasciculus connecting the anterior temporal pole to the frontobasal areas.
The relationship between severe myoclonic epilepsy of infancy (SMEI or Dravet syndrome) and the related syndrome
SMEI-borderland (SMEB) with mutations in the sodium channel alpha 1 subunit gene SCN1A is well established.
American Journal of Neuroradiology 28:528-530, March 2007
The purpose of this study was to evaluate the efficacy of a newly designed circular ring compression device that allows safe and effective glue injection during preoperative embolization of high-flow superficial craniofacial arteriovenous malformations (AVMs).
Current Opinion in Neurology. 20(2):208-212, April 2007
The purpose is to review recent papers on the prognosis of epilepsy, with an emphasis on the importance of considering the temporal aspects of epilepsy.
Despite well-documented discrepancies in many clinical conditions across insurance groups, limited research has examined insurance-related disparities for patients with stroke. This study examined the relationship between insurance status and hospital care for patients with stroke.
Child's Nervous System, Volume 23, Number 3, March 2007, pp. 265-267(3)
Visually evoked seizures have been reported for almost 2,000 years. This source of seizure activity, however, seems to have increased recently with the advent of new technologies used for television and computer games.
According to recent functional studies, the medial frontal lobe of the dominant hemisphere plays a role in both word generation and speech initiation. To our knowledge, speech arrest with intact facial expression secondary to the right anterior cingulate cortex (ACC) lesion has not been previously reported.
Child's Nervous System, Volume 23, Number 3, March 2007, pp. 343-347(5)
Neurofibromatosis type I (NF1) is one of the most prevalent genetic diseases of the nervous system. Although the majority of NF1 patients are only mildly affected, the risk of developing malignancies is significantly increased in this population.
Clinical Neurology and Neurosurgery Volume 109, Issue 3 , April 2007, Pages 302-304
We report a patient with recurrent glioblastoma, in whom serial magnetic resonance angiography
(MRA) demonstrated gradual enlargement of an artery feeding the tumor and the development of an intratumoral aneurysm that led to intratumoral hemorrhage.
American Journal of Neuroradiology 28:533-536, March 2007
Previously, endovascular treatment of wide-necked aneurysms and stenosis involving small vessels measuring <2 mm in diameter was limited. There are no reports in the literature addressing stent placement in small distal cerebral vessels. Recent experience with the Neuroform stent has shown that this device can be safely and effectively used to treat aneurysms in vessels of this caliber.
Archives of Physical Medicine and Rehabilitation Volume 88, Issue 3 , March 2007, Pages 338-345
To determine the efficacy of using modulated middle frequency alternating current
(MFAC) muscle stimulation for functional electric stimulation–propelled cycling by people with spinal cord injury (SCI) compared with the conventional method of using standard low-frequency rectangular pulses
(LFRP).
Archives of Physical Medicine and Rehabilitation Volume 88, Issue 3 , March 2007, Pages 374-380
To compare the psychometric properties (including the test-retest reliability, responsiveness, and predictive validity) of the Smart Balance Master
(SBM) system and the Postural Assessment Scale for Stroke patients (PASS) in patients with mild stroke.
Emotional distress is common in the aftermath of stroke and can impact negatively on the outcome. The study was aimed at evaluating whether religious beliefs can protect from emotional distress.
Archives of Physical Medicine and Rehabilitation Volume 88, Issue 3 , March 2007, Pages 386-388
Broadly defined, forced-use therapy uses specific techniques designed to engage the patient with brain injury in activities that disallow overcompensation with the noninvolved or less involved body segments while forcing the use of the more involved segments.
European Journal of Neuroscience, Volume 25, Number 3, February 2007, pp. 881-889(9)
Apart from being increasingly implicated in higher motor control, Broca's area is considered to play an important role in action understanding by coding the motor goal of an action.
Zambia suffers from a physician shortage, leaving the provision of care for those with epilepsy to nonphysician health care workers who may not be adequately trained for this task.
Disturbances of cerebrovascular autoregulation are thought to be involved in delayed cerebral ischemia and infarction after aneurysmal subarachnoid hemorrhage
(SAH). We hypothesized that the continuous monitoring of brain tissue oxygen (PtiO2) pressure reactivity enables the detection of impaired autoregulation after SAH and that impaired autoregulation is associated with delayed infarction.
Child's Nervous System, Volume 23, Number 3, March 2007, pp. 289-295(7)
The use of programmable shunt valves has increased dramatically in the practice of pediatric hydrocephalus. Despite theoretical advantages, it remains unclear if the use of programmable vs set-pressure valves affects shunt outcome.
Child's Nervous System, Volume 23, Number 3, March 2007, pp. 327-333(7)
Intracranial aneurysms are rare in children and have different epidemiological, clinical, and morphological characteristics and outcome from those in adults.
Neuroanatomical structure appears to be altered in preterm infants, but there has been little insight into the major perinatal risk factors associated with regional cerebral structural alterations.
Seventy-nine consecutive patients with symptomatic atherosclerotic stenosis 50% of intracranial vertebrobasilar artery (VBA) were treated by elective
stenting. There were five strokes within 30 days, and three strokes in the VBA territory after 30 days (mean of 812 days).
Journal of Pediatric Hematology/Oncology. 29(3):190-194, March 2007
Glioblastoma (GBM) is the most common adult malignant brain tumor but is notably less common in children. Primary brain tumors rarely metastasize outside the central nervous system and when metastases occur, it is often in patients with diversionary shunting of the cerebrospinal fluid. This report details the case of a 131/2-year-old boy who was diagnosed with
GBM.
International Urogynecology Journal, Volume 18, Number 3, March 2007, pp. 281-287(7)
The aim of this study was to evaluate the long-lasting effect of pelvic floor muscle training
(PFMT) in women with urinary incontinence after stroke measured by quality of life parameters.
Journal of Stroke and Cerebrovascular Diseases Volume 16, Issue 2 , March-April 2007, Pages 82-83
We report serial magnetic resonance imaging findings in a case of anoxic encephalopathy (AE). Diffusion-weighted images clearly showed early development of lesions in the cerebellum, cerebral cortex, and caudate
putamen, along with delayed manifestation of lesions in the hippocampus, corpus
callosum, and white matter.
Current Opinion in Neurology. 20(2):169-174, April 2007
To provide a critical review of studies published between December 2005 and November 2006, and detect the advances of basic and clinical research in epilepsy.
Current Opinion in Neurology. 20(2):203-207, April 2007
The surgical approach to nonlesional temporal lobe epilepsy presents a significant challenge due to uncertainties regarding the extent of resection necessary to result in a seizure-free state. To outline an optimum surgical strategy, an understanding of the clinical and diagnostic presentation of mesial and lateral temporal epilepsy is required in order to properly characterize the location of the ictal onset zone.
To compare the frequency and magnitude of head impacts between National Collegiate Athletic Association Division I and American high school football players. The long-term goal is to correlate impact forces with injury patterns, leading to improvements in protective headgear.
Radical surgery combined with postoperative radiation is recommended to achieve the best outcomes in patients suffering from malignant anterior skull base tumors.
The modified Rankin scale (mRS), a clinician-reported measure of global disability, is widely applied for evaluating stroke patient outcomes and as an end point in randomized clinical trials. Extensive evidence on the validity of the mRS exists across a large but fragmented literature. As new treatments for acute ischemic stroke are submitted for agency approval, an appreciation of the
mRS's attributes, specifically its relationship to other stroke evaluation scales, would be valuable for decision-makers to properly assess the impact of a new drug on treatment paradigms.
Daily variation in outdoor concentrations of inhalable particles (PM10 <10 µm in diameter) has been associated with fatal and nonfatal stroke. Toxicological and epidemiological studies suggest that smaller, combustion-related particles are especially harmful. We therefore evaluated the effects of several particle measures including, for the first time to our knowledge, ultrafine particles (<0.1
µm) on stroke.
Elevated systolic blood pressure (SBP) and lack of early vessel recanalization are predictors of poor outcome among patients with stroke treated with systemic tissue plasminogen activator
(tPA). We aimed to evaluate the potential relationship between pretreatment SBP and
tPA-induced recanalization.
Child's Nervous System, Volume 23, Number 3, March 2007, pp. 321-326(6)
Hemispheric brain lesions are commonly associated with early onset of catastrophic epilepsies and multiple seizure types. Hemispheric surgery is indicated for patients with unilateral intractable epilepsy. Although described more than 50 years ago, several new techniques for hemispherectomy have only recently been proposed aiming to reduce operatory risks and morbidity.
Cerebellar ataxic gait is characterized by unsteady movements and variable gait patterns. Previous studies have successfully identified pathological changes of balance-related gait parameters. However, it has been difficult to demonstrate deficits of joint coordination and the control of limb dynamics.
High-sensitivity C-reactive protein (hsCRP), a marker of inflammation, is associated with atherosclerosis, hypertensive target organ damage, and cardiovascular events. In the general Japanese population, the level of hsCRP is reported to be lower than that in Western countries, and the relationships among
hsCRP, silent cerebral infarcts (SCIs), and clinical stroke events in older Japanese hypertensives remain unclear.
To report the presence of microscopic neoplasms of the testis in men with anti-Ma2-associated encephalitis (Ma2-encephalitis) and to discuss the clinical implications.
Though less common than ischemic stroke, intracerebral hemorrhage (ICH) carries a much higher mortality. Despite the importance of this disorder, ICH is understudied. There are currently no Food and Drug Administration (FDA)-approved medical therapies available. It is accepted that the volume of the hematoma is the single strongest predictor of outcome after
ICH.
To evaluate the differences in brain activation in response to presentation of the patient's own name spoken by a familiar voice (SON-FV) in patients with VS and MCS.
Journal of Neurology, Neurosurgery, and Psychiatry 2007;78:342-349; doi:10.1136/jnnp.2006.106211
There are few data available on the causes and mechanistic basis, outcome and treatment of seizures and epilepsy in people with systemic cancer. Seizures and epilepsy in people with cancers other than primary brain tumours are reviewed here.
Journal of Neurology, Neurosurgery, and Psychiatry 2007;78:430-433
An extreme syndrome of the trephined after decompressive craniectomy is reported here. The most extensive clinical syndrome observed was established over 4 weeks and consisted of
bradypsychia, dysartria, and limb rigidity with equine varus feet predominating on the right.
Annals of Emergency Medicine Volume 49, Issue 4 , April 2007, Pages 508-514
Our objective is to determine whether a bedside ultrasonographic measurement of optic nerve sheath diameter can accurately predict the computed tomographic (CT) findings of elevated intracranial pressure in adult head injury patients in the emergency department (ED).
European Journal of Neurology, Volume 14, Number 3, March 2007, pp. 315-320(6)
C-reactive protein (CRP) increases following an acute stroke/transient ischemic attack (TIA), but the increment level varies among patients. We analyzed CRP concentrations during an acute stroke/TIA in relation to the CRP gene -717A>G polymorphism.
Clinical Neurology and Neurosurgery Volume 109, Issue 3 , April 2007, Pages 221-224
Cerebral palsy (CP) is a motor disorder due to cerebral damage. It is commonly associated with
neuro-psychological retardation and also with epilepsy; hence, its management warrants a multi-dimensional approach. In a significant number of CP patients, interictal epileptiform discharges
(IEDs) are obtained in their EEG even in absence of clinical epilepsy.
Archives of Physical Medicine and Rehabilitation Volume 88, Issue 3 , March 2007, Pages 309-314
To investigate the reliability, validity, and responsiveness of the Duruoz Hand Index
(DHI) in assessing activity limitation related to hand function in patients with stroke.
Pediatric Emergency Care. 23(3):137-141, March 2007
The malfunction of a ventricular shunt is one of the most common clinical problems encountered in pediatric neurosurgery. Standard emergency department (ED) evaluation of suspected shunt malfunction consists of plain radiographs of the skull, neck, chest, and abdomen (shunt series) to look for mechanical breaks, kinks, and disconnections in the shunt, and a cranial computed tomography (CT) scan to evaluate for signs of increased ventricular size.
Medical Image Analysis Volume 11, Issue 1 , February 2007, Pages 79-90
In this paper, we present the application of kernel Fisher discriminant in the statistical analysis of shape deformations that indicate the hemispheric location of an epileptic focus. The scans of two classes of patients with epilepsy, those with a right and those with a left anterior medial temporal lobe focus
(RATL and LATL), as validated by clinical consensus and subsequent surgery, were compared to a set of age and sex matched healthy volunteers using both volume and shape based features.
Clinical Endocrinology, Volume 66, Number 4, April 2007, pp. 503-507(5)
To assess the prevalence and characteristics of epilepsy in patients with
macroprolactinomas. Secondly, to report the response to dopamine agonist (DA) therapy.
The purpose of this survey was to compare attitudes and opinions regarding driving restrictions for persons with epilepsy
(PWE) between internal medicine and general practice physicians and neurologists.
The purpose of this survey was to compare attitudes and opinions regarding driving restrictions for persons with epilepsy
(PWE) between internal medicine and general practice physicians and neurologists.
It is a commonly held view that numbers are represented in an abstract way in both parietal lobes. This view is based on failures to find differences between various notational representations. Here we show that by using relatively smaller voxels together with an adaptation paradigm and analyzing subjects on an individual basis it is possible to detect specialized numerical representations.
Activation of the horizontal segment of the intraparietal sulcus (hIPS) has been observed in various number-processing tasks, whether numbers were conveyed by symbolic numerals (digits, number words) or by nonsymbolic displays (dot patterns).
European Journal of Neurology, Volume 14, Number 3, March 2007, pp. 248-254(7)
Normal pressure hydrocephalus (NPH) is characterized by disturbed cerebrospinal fluid
(CSF) dynamics and white matter lesions (WML). Although the morphology of these lesions is described, little is known about the biochemistry.
Child's Nervous System, Volume 23, Number 3, March 2007, pp. 335-341(7)
Traumatic epidural hematoma (EDH) represents a rare head injury complication in infants. Its diagnosis can be quite challenging because its clinical presentation is usually subtle and nonspecific. In our current communication, we present our data regarding the presentation of infants with
EDH, their management, and their long-term outcome.
We sought to evaluate the impact of the speed of recanalization on the evolution of diffusion- weighted imaging
(DWI) lesions and outcome in stroke patients treated with tissue-type plasminogen activator
(tPA).
Annals of Emergency Medicine Volume 49, Issue 4 , April 2007, Pages 403-407.e1
The Simplified Motor Score was recently found to exhibit equal test performance to the Glasgow Coma Scale (GCS) when predicting 4 clinically important trauma outcomes. The present study tests the interrater reliability of the Simplified Motor Scale, the GCS and its components, and 2 other simplified neurologic scales when applied to patients presenting to the emergency department with altered levels of consciousness from any cause.
Clinical Neurology and Neurosurgery Volume 109, Issue 3 , April 2007, Pages 292-298
Supratentorial hemangioblastomas (HBL) have been rarely described in the literature. Herein we report the fourth case of pituitary stalk HBL diagnosed concurrently with cerebellar HBLs in a 51-year-old woman with von Hippel-Lindau disease.
Clinical Neurology and Neurosurgery Volume 109, Issue 3 , April 2007, Pages 299-301
The authors present the 3D reconstructed CT angiography image of extravasation from a rebleeding aneurysm. Direct hemorrhage of a bleeding aneurysm into the lateral ventricle was detected by CT angiography.
Southern Medical Journal. 100(1):70-72, January 2007
Mitochondrial encephalopathy with lactic acidosis and stroke-like syndrome
(MELAS) is a progressive neurodegenerative disorder frequently complicated by diabetes mellitus and sensory neuronal hearing loss. This syndrome tends to present initially with stroke-like symptoms. These strokes are nonvascular in nature and are linked to mitochondrial defect such as transient oxidative phosphorylation dysfunction, which in turn results in encephalopathy.
Child's Nervous System, Volume 23, Number 3, March 2007, pp. 283-287(5)
There are few published large series on civilian craniocerebral gunshot injuries in children. Traumatic intracranial aneurysms
(TICAs) are rare and highly unstable lesions. They represent less than 1% of all aneurysms and can either rupture within minutes after formation or remain quiescent for several weeks or years, manifesting with delayed hemorrhage and neurologic deterioration.
It remains unclear whether or not and to what extent stereotactic radiosurgery can reduce the risk of first intracranial hemorrhage from brain arteriovenous malformations.
Patients with acute intracerebral hemorrhage (ICH) presenting within 3 hours of symptom onset are known to be at increased risk of expansion. However, only a minority arrive within this time frame. Therefore, alternative markers for expansion risk are needed.
To conduct a systematic review of the rehabilitation literature of moderate to severe acquired brain injuries
(ABI) from traumatic and non-traumatic causes.
The purpose of this review was to investigate the efficacy of rehabilitation interventions in acquired brain injury
(ABI) rehabilitation to provide guidance for clinical practice based on the best available evidence.
We sought to investigate the efficacy of treatment strategies used to manage motor impairments following acquired brain injury
(ABI) in order to provide guidance for clinical practice based on the best available evidence.
Cognitive rehabilitation represents a substantial portion of rehabilitative efforts put forth in increasing independence following an acquired brain injury.
The present study aimed to evaluate the effectiveness of prophylactic anticonvulsant pharmacological strategies for the prevention of seizure disorders following acquired brain injury
(ABI) to provide guidance for clinical practice based on the best available evidence.
To evaluate the effectiveness of interventional strategies for the common complications of heterotopic ossification (HO) and venous thromboembolism
(VTE) following acquired brain injury (ABI).
To evaluate the interventions and strategies used to enable transition from acute care or post-acute rehabilitation to the community following brain injury.
Pediatric Emergency Care. 23(3):148-153, March 2007
The local emergency medical services (EMS) council implemented a new pediatric treatment protocol using a Mucosal Atomization Device (MAD) to deliver intranasal (IN) midazolam for seizure activity.
American Journal of Clinical Oncology. 30(1):38-44, February 2007
We sought to model the feasibility of a simultaneous in field boost (SIB) to individual brain metastases during a course of whole brain radiotherapy
(WBXRT) using helical tomotherapy (HT) intensity-modulated radiation therapy.
Retrospectively assess the efficacy of lumbar cerebrospinal fluid (CSF) drainage placed preoperatively in skull base operations in decreasing the incidence of postoperative CSF fistula.
We wanted to investigate whether common prothrombotic mutations are more prevalent in patients with atrial fibrillation who have had a stroke than in healthy controls. We also wanted to assess whether early recurrent ischemic cerebrovascular events were more frequent among carriers of the factor V Leiden or the prothrombin gene mutations than among others.
European Journal of Neurology, Volume 14, Number 3, March 2007, pp. 255-261(7)
Valid classification of stroke is essential to initiate effective acute management and early secondary prevention strategies. To accurately evaluate stroke subtype a number of diagnostic procedures have to be performed. This study sought to investigate variations in use of diagnostic procedures across selected European hospitals.
Journal of Stroke and Cerebrovascular Diseases Volume 16, Issue 2 , March-April 2007, Pages 52-56
Aneurysms of the middle cerebral artery (MCA) trifurcation region are underrepresented in large series of endovascularly treated aneurysms. The purpose of our study was to evaluate the incidence of specific morphologic features of MCA bifurcation aneurysms that may affect suitability for endovascular treatment.
Journal of Stroke and Cerebrovascular Diseases Volume 16, Issue 2 , March-April 2007, Pages 64-70
In acute ischemic stroke, magnetic resonance diffusion-weighted imaging (DWI) is increasingly used to select patients for inclusion or as a surrogate outcome marker in clinical trials, or in routine practice. Little is known of what factors might affect DWI lesion size measurement.
Journal of Stroke and Cerebrovascular Diseases Volume 16, Issue 2 , March-April 2007, Pages 57-63
This study was conducted to evaluate the prognostic values of acute physiologic parameters of mortality and functional and cognitive recovery. We studied 108 patients with hemorrhagic stroke admitted within 24 hours after stroke onset to a neurologic intensive care department.
Current Opinion in Neurology. 20(2):188-193, April 2007
Status epilepticus refractory to first and second-line anticonvulsants represents an outstanding challenge to the medical team. This review covers new insights into the anaesthetic and intensive care of status
epilepticus.
American Journal of Neuroradiology 28:470-474, March 2007
Functional imaging studies suggest that poststroke recovery is related to the reorganization in both contralesional and ipsilesional prefrontal cortex. Little is known, however, about how longitudinal metabolic changes in prefrontal regions relate to the improvement after stroke. We sought to determine whether poststroke recovery is associated with changes in
N-acetylaspartate/creatine (NAA/Cr) ratio within contralesional prefrontal regions.
Current Opinion in Neurology. 20(2):194-202, April 2007
The aim of this article is to give a subjective review of the usefulness of single photon emission computed tomography
(SPECT) and positron emission tomography (PET) imaging in clinical practice in epilepsy for 2007.
There is an ongoing discussion about age limits for deep brain stimulation (DBS). Current indications for DBS are tremor-dominant disorders, Parkinsons disease, and
dystonia. Electrode implantation for DBS with analgesia and sedation makes surgery more comfortable, especially for elderly patients.
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