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Journal links archive: May 1-15 2008 April 16-30 2008 April 1-15 2008 March 16-31 2008 March 1-15 2008 February 16-29 2008 February 1-15 2008 January 16-31 2008 January 1-15 2008 December 16-31 2007 December 1-15 2007 November 16-30 2007 November 1-15 2007 October 16-31 2007 October 1-15 2007 September 16-30 2007 September 1-15 2007 August 16-31 2007 August 1-15 2007 July 16-31 2007 July 1-15 2007 June 16-30 2007 June 1-15 2007 May 16-31 2007 May 1-15 2007 April 16-30 2007 April 1-15 2007 March 16-31 2007 March 1-15 2007 February 16-28 2007 February 1-15 2007 January 16-31 2007 January 1-15 2007 December 16-31 2006 December 1-15 2006 November 16-30 2006 November 1-15 2006 October 16-31 2006 October 1-15 2006 September 16-30 2006 September 1-15 2006 August 16-31 2006 August 1-15 2006 July 16-31 2006 July 1-15 2006 June 16-30 2006 June 1-15 2006 May 16-31 2006 May 1-15 2006 April 16-30 2006 April 1-15 2006 March 16-31 2006 March 1-15 2006 February 2006 January 2006

January 16-31 2008 Postings (Note: Some archived links may become inactive)

01/31/2008 07:52 PM

Mild Traumatic Brain Injury in U.S. Soldiers Returning from Iraq

New England Journal of Medicine Volume 358:453-463 January 31, 2008 Number 5

An important medical concern of the Iraq war is the potential long-term effect of mild traumatic brain injury, or concussion, particularly from blast explosions. However, the epidemiology of combat-related mild traumatic brain injury is poorly understood.

01/31/2008 07:48 PM

Disentangling Mild Traumatic Brain Injury and Stress Reactions

New Enmgland Journal of Medicine Volume 358:525-527 January 31, 2008 Number 5

The study by Hoge and colleagues in this issue of the Journal provides an important profile of the sequelae of mild traumatic brain injury in military personnel after combat.1 The findings demonstrate that mild traumatic brain injury results in increased rates of psychological, health, and functional problems. Although the study provides strong evidence for impairments in military personnel serving in Iraq and Afghanistan, it also raises a number of critical questions concerning the impairments that may be attributed to mild traumatic brain injury.

01/31/2008 07:28 PM

Closing the survival gap - Implementation of medulloblastoma protocols in a low-income country through a twinning program

International Journal of Cancer Volume 122, Issue 6 , Pages 1203 - 1206

Successful twinning initiatives have been reported in childhood leukemia. Pediatric neuro-oncology requires a complex multidisciplinary approach and the feasibility of similar twinning programs is unknown. Twinning between King Hussein Cancer Center in Amman and the Hospital for Sick Children in Toronto started with e-mail communications, and subsequently included monthly videoconferences and exchanges between institutions.

01/31/2008 07:25 PM

Memory deficit after traumatic brain injury - how big is the problem in New Zealand and what management strategies are available

Journal of the New Zealand Medical Association, 25-January-2008, Vol 1268 No 121

Traumatic brain injury (TBI) impacts a significant portion of individuals, and can have lasting consequences. One of the most common and persistent difficulties experienced post-TBI is deficits in memory, which impact up to 80% of TBI survivors.

01/31/2008 07:24 PM

Plasma vitamin C concentrations predict risk of incident stroke over 10 y in 20 649 participants of the European Prospective Investigation into Cancer-Norfolk prospective population study

American Journal of Clinical Nutrition, Vol. 87, No. 1, 64-69, January 2008

The relation between plasma vitamin C and risk of stroke remains unclear. Although clinical trials showed no significant benefit of vitamin C supplementation in reducing stroke risk, they were not able to examine the relation between plasma vitamin C concentrations and stroke risk in a general population.

01/31/2008 07:23 PM

Causes of Seizures in the Elderly

U.S. Pharmasist Vol. No: 33:1 Posted: 1/24/2008

A variety of neurologic conditions present more often in individuals of advancing age. Among seniors, the majority of seizure disorders are secondary to symptomatic causes that are frequently age-related.

01/31/2008 07:22 PM

Treatment of myoclonic seizures in patients with juvenile myoclonic epilepsy

Neuropsychiatric Disease and Treatment Issue: 2007, Volume 3 Issue 6

Drug treatment of Juvenile myoclonic epilepsy (JME) is mainly based on clinical experience and prospective and retrospective studies, with little evidence from randomized clinical trials. There are no head-to-head comparisons between old and new antiepileptic drugs (AEDs) and no drugs licensed specifically for JME.

01/31/2008 07:20 PM

Management of epilepsy in the elderly

Issue: 2007, Volume 3 Issue 6

Epilepsy among the elderly is a frequently occurring pathology, differing in etiology, clinical presentation and prognosis from those of young people. In addition, beyond a certain age, physiological modifications are produced in the metabolism which alter the pharmacokinetics of antiepileptic drugs (AEDs), increasing the risk of pharmacological interactions, already greater in these patients due to the frequency of poly-pharmacy. Furthermore, elderly patients are particularly sensitive to certain secondary effects of AEDs, as for example, cognitive disturbances, osteoporosis or weight increase.

01/31/2008 07:18 PM

Neuropsychiatric Disease and Treatment

Issue: 2007, Volume 3 Issue 6

Primary progressive aphasia (PPA) is a neurodegenerative disease of insidious onset presenting with progressive isolated loss of language function, without significant impairment in other cognitive domains.

01/31/2008 07:17 PM

Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis

Neuropsychiatric Disease and Treatment Issue: 2007, Volume 3 Issue 6

We report a case of acute demyelinating encephalitis that occurred after viral vaccination against hepatitis A-, hepatitis B-, and poliovirus and vaccination against bacterial toxins of diphtheria and tetanus. After different diagnosis had been excluded, we diagnosed postvaccinal demyelinating encephalitis and started treatment with high dose intravenous methylprednisolone, followed by peroral application in decreasing dosages for three weeks.

01/31/2008 07:14 PM

Neural cell adhesion molecule NCAM isoform expression is associated with neuroblastoma differentiation status

Pediatric Blood & Cancer Published Online: 22 Jan 2008

NCAM protein expression was measured in a neuroblastic tumor tissue microarray (N = 185) by immunohistochemistry. Relative expression of NCAM mRNA isoforms was measured in a panel of 24 human neuroblastomas and compared to fetal and adult human brain using real-time quantitative PCR and Western blot analysis. Associations with clinical and tumor biological co-variates were performed.

01/31/2008 07:12 PM

Does Hyperventilation Improve Operating Condition During Supratentorial Craniotomy - A Multicenter Randomized Crossover Trial

Anesth Analg 2008; 106:585-594

Hyperventilation has been an integral, but poorly validated part of neuroanesthetic practice. We conducted a two-period, crossover, randomized trial to evaluate surgeon-assessed brain bulk and measured intracranial pressure (ICP) in patients undergoing craniotomy for removal of supratentorial brain tumors during moderate hypocapnia or normocapnia.

01/31/2008 07:10 PM

Cerebral Border Zones between Distal End Branches of Intracranial Arteries: MR Imaging

Radiology 2008;246:572-580

This study had institutional review board approval; informed consent was obtained from all participants. The study purpose was to prospectively determine whether a longer arterial transit time (ATT), from the proximal vasculature in the neck toward the distal end branches of the intracranial arteries, can be utilized to identify cerebral border zone regions.

01/31/2008 07:08 PM

Topiramate in the treatment of partial and generalized epilepsy

Neuropsychiatric Disease and Treatment Issue: 2007, Volume 3 Issue 6

Topiramate (TPM) is a widely-used drug for the treatment of epilepsy. It is useful for several types of partial-onset and generalized-onset seizures, and is therefore considered a broad-spectrum agent. It is also effective as a prophylactic against migraine headaches.

01/31/2008 07:05 PM

Interventions for motor apraxia following stroke

Cochrane Database of Systematic Reviews 2008 Issue 1

Apraxia is a cognitive disorder that can occur after stroke. It prevents a person from carrying out a learned movement. Various interventions are used to treat apraxia but evidence of their benefit has been lacking.

01/31/2008 07:01 PM

Factors Predicting Survival following Noninvasive Ventilation in Amyotrophic Lateral Sclerosis

Eur Neurol 2008;59:164-171

The involvement of respiratory muscles is a major predicting factor for survival in amyotrophic lateral sclerosis (ALS). Recent studies show that noninvasive ventilation (NIV) can relieve symptoms of alveolar hypoventilation. However, factors predicting survival in ALS patients when treated with NIV need to be clarified.

01/31/2008 06:59 PM

Management of patients with newly diagnosed malignant primary brain tumors with a focus on the evolving role of temozolomide

Therapeutics and Clinical Risk Management Issue: 2007, Volume 3, Issue 6

The prognosis for patients with newly diagnosed malignant gliomas remains poor; however there have been some recent advances in treatment that have generated optimism. Medical management usually includes administration of corticosteroids to control peritumoral edema.

01/31/2008 06:58 PM

BrainStem Encephalitis Associated with Chandipura in Andhra Pradesh Outbreak

Journal of Tropical Pediatrics 2008 54(1):25-30

Clinical data of 104 hospitalized children during the 2003 epidemic of encephalitis in Andhra Pradesh state was retrospectively analysed to know the clinical profile and risk factors associated with mortality.

01/31/2008 06:57 PM

Characterization of non-linear relationship between total and unbound serum concentrations of valproic acid in epileptic children

Journal of Clinical Pharmacy & Therapeutics, Volume 33, Number 1, February 2008 , pp. 31-38(8)

To establish a regression equation to properly estimate the unbound serum concentration of valproic acid (VPA) from its total serum concentration; the relationship between total and unbound serum VPA concentrations was retrospectively characterized.

01/31/2008 06:54 PM

Using magnetic resonance microscopy to study the growth dynamics of a glioma spheroid in collagen I - a case study

BMC Medical Imaging 2008, 8:3

Highly malignant gliomas are characterized by rapid growth, extensive local tissue infiltration and the resulting overall dismal clinical outcome. Gaining any additional insights into the complex interaction between this aggressive brain tumor and its microenvironment is therefore critical.

01/31/2008 06:53 PM

Bridging the gap - the effectiveness of teaming a stroke coordinator with patient's personal physician on the outcome of stroke

Age and Ageing 2008 37(1):32-38

To test the hypothesis as to whether persons newly discharged into the community following an acute stroke and assigned a stroke case manager would experience, compared to usual post-hospital care, better health-related quality of life (HRQL), fewer emergency room visits and less non-elective hospitalisations.

01/31/2008 06:51 PM

Parkinsonism and tardive antecollis in frontotemporal dementia - increased sensitivity to newer antipsychotics

European Journal of Neurology, Volume 15, Number 2, February 2008 , pp. 199-201(3)

Frontotemporal dementia (FTD) often presents with behavioural changes warranting treatment with antipsychotic medications. It is known that patients with Lewy body dementia are sensitive to developing extrapyramidal symptoms (EPS) from these medications.

01/31/2008 06:50 PM

Impact of functional status at six months on long term survival in patients with ischaemic stroke - prospective cohort studies

BMJ, doi:10.1136/bmj

To estimate the impact on long term survival of functional status at six months after ischaemic stroke.

01/31/2008 06:48 PM

Urban-rural differences in pediatric traumatic head injuries - A prospective nationwide study

Neuropsychiatric Disease and Treatment Issue: 2007, Volume 3 Issue 6

To estimate differences in the incidence of recorded traumatic head injuries by gender, age, severity, and geographical area.

01/31/2008 06:47 PM

Profile and associations of central pulse wave velocity and central pulse pressure among ischemic stroke patients

European Journal of Neurology, Volume 15, Number 2, February 2008 , pp. 196-198(3)

Arterial stiffness, a known risk factor for atherosclerosis, can be measured directly with carotid-femoral pulse wave velocity (CPWV) and indirectly with central pulse pressure (CPP).

01/31/2008 06:44 PM

Care delivery and self-management strategies for adults with epilepsy

Cochrane Database of Systematic Reviews 2008, Issue 1

Epilepsy care has been criticised for its lack of impact. Various service models and strategies have been developed in response to perceived inadequacies in care provision.

01/31/2008 06:40 PM

Hypothermia Treatment for Traumatic Brain Injury - A Systematic Review and Meta-Analysis

Journal of Neurotrauma. January 1, 2008, 25(1): 62-71

In this study, we conducted an updated meta-analysis of the effects of hypothermia therapy on mortality, favorable neurologic outcome, and associated adverse effects in adults with traumatic brain injury (TBI) for use by Brain Trauma Foundation (BTF)/American Association of Neurological Surgeons (AANS) task force to develop evidence-based treatment guidelines.

01/31/2008 06:39 PM

Risk of Cervical Spine Injury and Other Complications Seen with Skull Fractures in the Setting of Mild Closed Head Injury in Young Children - A Retrospective Study

Pediatr Neurosurg 2008;44:124-127

We have reviewed records for patients under 2 years of age who presented at our hospital with mild closed head injuries and nondisplaced skull fractures, specifically to examine methods utilized for spine clearance, associated cervical injuries, involvement and findings of child protective services and delayed complications.

01/31/2008 06:37 PM

Lack of evidence for an association between UCHL1 S18Y and Parkinson's disease

European Journal of Neurology, Volume 15, Number 2, February 2008 , pp. 134-139(6)

UCHL1 has been proposed as a candidate gene for Parkinson's disease (PD). A meta-analysis of white and Asian subjects reported an inverse association between the non-synonymous UCHL1 S18Y polymorphism and PD risk.

01/31/2008 06:35 PM

Is quality of life in non-demented Parkinson's disease patients related to cognitive performance - A clinic-based cross-sectional study

European Journal of Neurology, Volume 15, Number 2, February 2008 , pp. 128-133(6)

Whilst the association between dementia and poorer health-related quality of life (Hr-QoL) in Parkinson's disease (PD) has been well established, we aimed to explore the relationship between cognitive performance and Hr-QoL in PD without dementia.

01/31/2008 06:34 PM

Consequences of Mild Traumatic Brain Injury on Information Processing Assessed with Attention and Short-Term Memory Tasks

Neurotrauma. January 1, 2008, 25(1): 30-37

In this investigation, we explored the impact of mild traumatic brain injury (mTBI) upon short term or working memory and attention.

01/31/2008 06:33 PM

Effect of High Temperature on Neuromuscular Jitter in Myasthenia Gravis

Eur Neurol 2008;59:179-182

To examine if the effect of temperature on neuromuscular jitter differs in myasthenics and normals, we performed single fiber electromyography (SFEMG) in 10 myasthenics and 10 healthy controls after heating the upper extremity to 37 and 42°C.

01/31/2008 06:31 PM

Proton radiosurgery in neurosurgery

Neurosurgical Focus December 2007 Volume 23, Number 6

Photon energy deposition from gamma or photon sources follows the law of exponential decay. Consequently, energy is deposited over the entire path of the radiation beam, resulting in dose distribution before and after the target is reached. In contrast, the physical properties of protons are such that energy deposition occurs with no exit dose beyond the target volume. Therefore, relative to photons, proton beams represent a superior platform for the administration of radiosurgery.

01/29/2008 05:37 PM

Traumatic vs non-traumatic spinal cord lesions: comparison of neurological and functional outcome after in-patient rehabilitation

Spinal Cord advance online publication 29 January 2008; doi: 10.1038/sj.sc.3102168

To compare neurological and functional outcome and length of stay of persons with traumatic vs non-traumatic spinal cord lesion (SCL) after in-patient rehabilitation.

01/29/2008 05:36 PM

The prevalence of deep vein thrombosis in a cohort of patients with spinal cord injury following the Pakistan earthquake of October 2005

Spinal Cord advance online publication 29 January 2008; doi: 10.1038/sj.sc.3102170

To assess the prevalence of symptomatic deep vein thrombosis (DVT) in earthquake survivors with spinal cord injury (SCI).

01/29/2008 05:35 PM

Neuromuscular electrical stimulation of completely paralyzed abdominal muscles in spinal cord-injured patients - a pilot study

Spinal Cord advance online publication 29 January 2008; doi: 10.1038/sj.sc.3102166

The effect of abdominal neuromuscular electrical stimulation (NMES) in patients with spinal cord injury. The principal parameters observed in this study are lung capacity, colonic transit, patient satisfaction of used method and of aesthetics effect on abdominal wall.

01/29/2008 05:34 PM

International Urodynamic Basic Spinal Cord Injury Data Set

Spinal Cord advance online publication 29 January 2008; doi: 10.1038/sj.sc.3102174

To create the International Urodynamic Basic Spinal Cord Injury (SCI) Data Set within the framework of the International SCI Data Sets.

01/29/2008 05:33 PM

THE FIRST CEREBROTENDINOUS XANTHOMATOSIS FAMILY FROM ARGENTINA - A NEW MUTATION IN - Szlago et al

Neurology.2008; 70: 402-404

01/29/2008 05:32 PM

Teaching NeuroImage - One-and-a-half syndrome

NEUROLOGY 2008;70:e20

A 28-year-old right-handed man with no medical history presented with sudden onset of double vision. The patient stated that the double vision was worse when looking to the right, and he was not able to move his eyes to the left. On examination, the patient had a conjugate gaze palsy to the left and impaired adduction in the left eye (video), which persisted during saccades, pursuit, and oculocephalic movements.

01/29/2008 05:31 PM

RECANALIZATION AFTER INTRAVENOUS THROMBOLYSIS - DOES A RECANALIZATION TIME WINDOW

Neurology.2008; 70: 406-407

01/29/2008 05:30 PM

Practical approaches to incidental findings in brain imaging research

NEUROLOGY 2008;70:384-390

A decade of empirical work in brain imaging, genomics, and other areas of research has yielded new knowledge about the frequency of incidental findings, investigator responsibility, and risks and benefits of disclosure.

01/29/2008 05:29 PM

Polyarteritis nodosa presenting with bilateral cavernous internal carotid artery

Neurology.2008; 70: 405

01/29/2008 05:28 PM

Neuropathy progression in Charcot-Marie-Tooth disease type 1A

NEUROLOGY 2008;70:378-383

To determine the rate of disease progression in Charcot-Marie-Tooth disease type 1A (CMT1A).

01/29/2008 05:27 PM

Neuromyelitis optica - IgG in childhood inflammatory demyelinating CNS disorders

NEUROLOGY 2008;70:344-352

To determine seroprevalence of neuromyelitis optica (NMO)-IgG in childhood CNS inflammatory demyelinating disorders.

01/29/2008 05:26 PM

LONG-TERM OUTCOME IN PCNSL PATIENTS TREATED WITH HIGH-DOSE METHOTREXATE AND DEFERRED

Neurology.2008; 70: 401-402

01/29/2008 05:25 PM

Limited chronic focal encephalitis - Another variant of Rasmussen syndrome

NEUROLOGY 2008;70:374-377

To describe a more limited and less malignant form of Rasmussen encephalitis (RE).

01/29/2008 05:25 PM

Firing pattern of fasciculations in ALS Evidence for axonal and neuronal origin

NEUROLOGY 2008;70:353-359

In amyotrophic lateral sclerosis (ALS), the origin of fasciculations is disputed. We hypothesized that the discharge pattern of fasciculation potentials (FPs) would be different for FPs arising in the motor axon or in the spinal motor neuron.

01/29/2008 05:24 PM

Finding NMO - Neuromyelitis optica in children Levy et al

Neurology.2008; 70: 334-335

01/29/2008 05:23 PM

Cortical demyelination in PML and MS

NEUROLOGY 2008;70:336-343

To characterize pathologic changes in the cerebral cortex of patients with multiple sclerosis (MS) and progressive multifocal leukoencephalopathy (PML).

01/29/2008 05:22 PM

Cortical demyelination in CNS inflammatory demyelinating diseases Lassmann and Lucchinetti

Neurology.2008; 70: 332-333

01/29/2008 05:21 PM

BRAIN EMBOLISM

Neurology.2008; 70: 409

01/29/2008 05:19 PM

Body mass index and cognitive decline in a biracial community population

NEUROLOGY 2008;70:360-367

To examine whether a higher body mass index (BMI) in older adults is associated with greater cognitive decline.

01/29/2008 05:18 PM

Historical Neurology - Alexia and agraphia Contrasting perspectives of JM Charcot and J Hughlings Jackson

NEUROLOGY 2008;70:391-400

To evaluate 19th-century concepts of cerebral localization for complex mental activities, focusing on alexia and agraphia in published writings of Jean-Martin Charcot (1825-1893) and John Hughlings Jackson (1835-1911).

01/25/2008 07:08 PM

3-T Contrast-Enhanced MR Angiography in Evaluation of Suspected Intracranial Aneurysm - Comparison with MDCT Angiography

AJR 2008; 190:389-395

The purpose of this study was to prospectively evaluate a high-spatial-resolution contrast-enhanced 3-T MR angiography protocol for detection and characterization of intracranial aneurysms and to compare the results with those of MDCT angiography.

01/25/2008 07:05 PM

Use Of Tenoxicam For Post Craniotomy Pain Relief With Or Without Bupivacaine Scalp Infiltration - A Randomized Study

Internet Journal of Anesthesiology. 2008. Volume 15 Number 2

Craniotomies are generally thought to be less painful than other operations, but this assumption has been challenged. Researchers have used different regimens of postcraniotomy pain relief including intravenous tramadol , codien, piritramide, paracetamol, nalbuphine PCA with oxycodone , morphine, intramuscular ketoprofen, prepinning scalp infiltration of bupivacain 0.25% or ropivacain.

01/25/2008 07:02 PM

Surgical outcome of patients with mesial temporal lobe epilepsy related to hippocampal sclerosis

Epilepsia doi:10.1111/j.1528-1167.2007.01503.x

Seizure outcome in mesial temporal lobe epilepsy related to hippocampal sclerosis (MTLE-HS) that was evaluated according to a noninvasive protocol was assessed in 165 patients and reported using both Engel's and ILAE classifications.

01/25/2008 07:00 PM

The role of endothelin in the cerebrovascular response following intracerebral haemorrhage - experimental studies using the endothelin antagonist SB209670

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , pages 35 - 39

Primary intracerebral haemorrhage (ICH) is associated with considerable morbidity and mortality. Local endothelin release following ICH may contribute to the pathophysiology of perilesional ischaemia.

01/25/2008 06:59 PM

The role of 3D-computed tomography angiography 3D-CTA in investigation of spontaneous subarachnoid haemorrhage - comparison with digital subtraction angiography DSA and surgical findings

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , pages 71 - 78

Spontaneous subarachnoid haemorrhage is a clinical condition that may be attributed to various underlying causes, such as rupture of intracranial aneurysms and arteriovenous malformations (AVMs).

01/25/2008 06:58 PM

The Pseudotumour Cerebri Syndrome - Pseudotumour Cerebri Idiopathic Intracranial Hypertension Benign Intracranial Hypertension and Related Conditions

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , pages 139 - 140

01/25/2008 06:57 PM

Surgical treatment of aneurysmal subarachnoid haemorrhage in the presence of 24-h endovascular availability - management and results

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , pages 53 - 62

Endovascular treatment of ruptured intracranial aneurysms increasingly supersedes surgical repair. This study focuses on the management and results in 109 individuals treated surgically when both treatment modalities were available.

01/25/2008 06:55 PM

Supraorbital microcraniotomy for acute aneurysmal subarachnoid haemorrhage - results of first 50 cases

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , pages 40 - 45

For the past 50 years the pterional craniotomy has been the standard approach for anterior circulation aneurysms. However, this is a major procedure. As the trend is towards minimally invasive surgery generally, we have been developing a minimally invasive approach for anterior circulation aneurysms - the supraorbital microcraniotomy.

01/25/2008 06:54 PM

Sixteen-row multislice computerized tomography angiography in the postoperative evaluation of patients with intracranial aneurysms

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , pages 63 - 70

The goal of this study was to assess the diagnostic accuracy of 16-row multislice computed tomography angiography (CTA) compared with digital subtraction angiography (DSA) in the detection of aneurysm remnants and arterial patency after clipping of intracranial aneurysms.

01/25/2008 06:53 PM

Radiographic Atlas of Skull and Brain Anatomy

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , page 139

01/25/2008 06:52 PM

Multiple extra-axial adenocarcinomas mimicking meningiomas - a case report

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , pages 123 - 125

We present the case of multiple meningeal tumours in the right sphenoid ridge and left parafalcine region. Magnetic resonance imaging disclosed homogenous enhancement.

01/25/2008 06:51 PM

Gustatory disturbance due to a cerebellar hemangioblastoma

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , pages 110 - 112

01/25/2008 06:50 PM

Foramen magnum decompression and expansile duroplasty for acquired Chiari type I malformation in craniometaphyseal dysplasia

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , pages 83 - 85

Craniometaphyseal dysplasia (CMD) is a rare genetic bone remodelling disorder characterized by undertubulation of the long bones and sclerosis and hyperostosis of the skull base with cranial nerve impairment.

01/25/2008 06:49 PM

Fluorescein sodium-guided surgery in glioblastoma multiforme - a prospective evaluation

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , pages 99 - 103

We have evaluated the influence of fluorescein-guided resection on gross total resection (GTR) and survival in a series of patients with GBM. Group 1 consisted of 47 patients given fluorescein and group 2 comprised 33 patients, on whom fluorescein was not used.

01/25/2008 06:48 PM

Extruded aneurysm coils found at craniotomy - report of two cases

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , pages 131 - 134

The operative findings are presented in two patients following inadequate coil embolization. At craniotomy, part of the coil mass had extruded through the fundus of both aneurysms. It is unclear if this phenomenon is confined to aneurysms that demonstrate significant regrowth and if there is an increased risk of rebleeding.

01/25/2008 06:47 PM

European Working Time Directive Aneurysm Surgery and Scalp Clips

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , pages 1 - 2

01/25/2008 06:46 PM

Endovascular management of ruptured cerebral mycotic aneurysms

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , pages 46 - 52

Abstract The purpose of this investigation was to evaluate the current endovascular management of cerebral mycotic aneurysms. We report the retrospective evaluation of data of patients with cerebral mycotic aneurysms treated with endovascular approach.

01/25/2008 06:45 PM

Clinical studies in spinal cord injury - moving towards successful trials

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , pages 3 - 12

Spinal cord injury is a devastating condition for which there is still no cure. Many new therapies have emerged in the past few decades that have attempted to improve the outcome after injury, with varying levels of supporting experimental and clinical data.

01/25/2008 06:44 PM

Children's Cancer and Leukaemia Group CCLG - guidelines for the management of intracranial meningioma in children and young people

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , pages 13 - 25

Primary tumours of the meninges occur extremely rarely in children and young people (less than five new cases annually in the UK) and have remained a poorly defined group compared with the common diagnosis of meningiomas in adults.

01/25/2008 06:43 PM

Association of intracranial hypertension without ventriculomegaly and Chiari malformation - a dangerous combination

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , pages 113 - 115

With the increased use of MRI, tonsillar ectopia, the hallmark of the adult Chiari malformation (ACM) is being more frequently recognized. However, in some cases, the patient's symptoms do not fit with the classical presentation for ACM, but are similar to intracranial hypertension (IH). The latter may be difficult to diagnose in absence of ventricular enlargement. We report a case of ACM and IHWV due to carcinomatous meningitis.

01/25/2008 06:42 PM

A case report of the management of multiple metachronous haemangioblastomas in a patient with von Hippel - Lindau disease

British Journal of Neurosurgery, Volume 22, Issue 1 February 2008 , pages 104 - 106

Cerebellar haemangioblastomas commonly arise in patients with von Hippel - Lindau disease. We present the case of a 47-year-old male who has successfully undergone 10 separate procedures for symptomatic cerebellar haemangioblastomas. To our knowledge, this case is unique with respect to the frequency of symptomatic recurrences.

01/25/2008 06:41 PM

The Experience of Fatigue in the First 2 Years After Moderate-to-Severe Traumatic Brain Injury - A Preliminary Report.

Journal of Head Trauma Rehabilitation. Fatigue After Traumatic Brain Injury. 23(1):17-24, January/February 2008

Fatigue is a well-recognized issue for individuals with traumatic brain injury (TBI). This prospective study examined the rate and types of fatigue that are experienced by a cohort of individuals with TBI within the first 2 years, using a multidimensional fatigue scale.

01/25/2008 06:40 PM

Post-TBI Fatigue

Journal of Head Trauma Rehabilitation. Fatigue After Traumatic Brain Injury. 23(1):2, January/February 2008

Preface.

01/25/2008 06:39 PM

Patterns of Fatigue and Its Correlates Over the First 2 Years After Traumatic Brain Injury

Journal of Head Trauma Rehabilitation. Fatigue After Traumatic Brain Injury. 23(1):25-32, January/February 2008

This study used a prospective longitudinal design to quantify fatigue and associated factors during the first 2 years after traumatic brain injury (TBI). Fifty-one individuals were assessed at 3 time points: within the first 6, 12, and 18-24 months after TBI. Self-reported fatigue improved during the first year, as did pain, sleep quality, cognitive independence, and involvement in productive activity.

01/25/2008 06:38 PM

Objective Measurement of Fatigue Following Traumatic Brain Injury

Journal of Head Trauma Rehabilitation. Fatigue After Traumatic Brain Injury. 23(1):33-40, January/February 2008

To quantify posttraumatic brain injury (post-TBI) mental fatigue objectively by documenting changes in performance on neuropsychological tests as a result of sustained mental effort and to examine the relationship between objectively measured mental fatigue and self-reported situational and day-to-day fatigue.

01/25/2008 06:37 PM

Fatigue After Traumatic Brain Injury and Its Impact on Participation and Quality of Life

Journal of Head Trauma Rehabilitation. Fatigue After Traumatic Brain Injury. 23(1):41-51, January/February 2008

To examine the relationships between post-TBI fatigue (PTBIF) and comorbid conditions, participation in activities, quality of life, and demographic and injury variables.

01/25/2008 06:37 PM

Assessing Fatigue After Traumatic Brain Injury - An Evaluation of the Barroso Fatigue Scale

Journal of Head Trauma Rehabilitation. Fatigue After Traumatic Brain Injury. 23(1):3-16, January/February 2008

To assess the suitability of the Barroso Fatigue Scale (BFS) for assessment of posttraumatic brain injury (post-TBI) fatigue.

01/25/2008 06:35 PM

A Randomized Trial of Modafinil for the Treatment of Fatigue and Excessive Daytime Sleepiness in Individuals with Chronic Traumatic Brain Injury

Journal of Head Trauma Rehabilitation. Fatigue After Traumatic Brain Injury. 23(1):52-63, January/February 2008

This study examines the efficacy of modafinil in treating fatigue and excessive daytime sleepiness in individuals with traumatic brain injury (TBI).

01/25/2008 06:34 PM

Sensorineural Deafness and Seizures in Mice Lacking Vesicular Glutamate Transporter 3

Neuron, Vol 57, 263-275, 24 January 2008

The expression of unconventional vesicular glutamate transporter VGLUT3 by neurons known to release a different classical transmitter has suggested novel roles for signaling by glutamate, but this distribution has raised questions about whether the protein actually contributes to glutamate release.

01/25/2008 06:33 PM

New Experiences Enhance Coordinated Neural Activity in the Hippocampus

Neuron, Vol 57, 303-313, 24 January 2008

The acquisition of new memories for places and events requires synaptic plasticity in the hippocampus, and plasticity depends on temporal coordination among neurons.

01/25/2008 06:32 PM

Impaired Spatial Representation in CA1 after Lesion of Direct Input from Entorhinal Cortex

Neuron, Vol 57, 290-302, 24 January 2008

Place-specific firing in the hippocampus is determined by path integration-based spatial representations in the grid-cell network of the medial entorhinal cortex. Output from this network is conveyed directly to CA1 of the hippocampus by projections from principal neurons in layer III, but also indirectly by axons from layer II to the dentate gyrus and CA3. The direct pathway is sufficient for spatial firing in CA1, but it is not known whether similar firing can also be supported by the input from CA3.

01/25/2008 06:31 PM

Behavioral Shifts and Action Valuation in the Anterior Cingulate Cortex

Neuron, Vol 57, 314-325, 24 January 2008

Rapid optimization of behavior requires decisions about when to explore and when to exploit discovered resources. The mechanisms that lead to fast adaptations and their interaction with action valuation are a central issue. We show here that the anterior cingulate cortex (ACC) encodes multiple feedbacks devoted to exploration and its immediate termination.

01/25/2008 02:21 PM

Review of stroke rehabilitation

BMJ 2007;334:86-90 (13 January)

The many definitions of rehabilitation, most of which apply well to stroke, can be confusing. However, a clear consensus exists that the purpose of rehabilitation is to limit the impact of stroke related brain damage on daily life by using a mixture of therapeutic and problem solving approaches.

01/24/2008 04:22 PM

Retinoic acid downregulates Rae1 leading to APC Cdh1 activation and neuroblastoma SH-SY5Y differentiation

Oncogene January 2008

In neuroblastoma cells, retinoic acid induces cell cycle arrest and differentiation through degradation of the F-box protein, Skp2, and stabilization of cyclin-dependent kinase inhibitor, p27. However, the mechanism responsible for retinoic acid-mediated Skp2 destabilization is unknown. Since Skp2 is degraded by anaphase-promoting complex (APC)Cdh1, here we studied whether retinoic acid promotes differentiation of human SH-SY5Y neuroblastoma cells by modulating Cdh1.

01/24/2008 03:52 PM

Regulation of glioblastoma cell invasion by PKC and RhoB

Oncogene January 2008

Glioblastoma multiforme is the most aggressive form of primary brain tumor and remains largely incurable, in large part, due to its highly invasive nature.

01/24/2008 03:49 PM

Childhood Craniopharyngioma Recent Advances in Diagnosis Treatment and Follow-Up

Horm Res 2008;69:193-202

Craniopharyngioma are embryogenic malformations of the sellar area. With an overall incidence of 0.5-2 new cases per million population per year, 30-50% of all cases occur in childhood.

01/24/2008 03:48 PM

Emergency department measurement of urinary S100B in children following head injury: can extracranial injury confound findings

Emergency Medicine Journal 2008;25:88-89

To assess the potential role of urinary S100B as a prognostic biochemical marker following head injury in children in a UK emergency department setting.

01/24/2008 03:46 PM

Robotics and its applications in stereotactic radiosurgery

Neurosurgical Focus December 2007 Volume 23, Number 6

Stereotactic radiosurgery has undergone a remarkable evolution since its conception and the subsequent introduction of image-guided radiosurgery, primarily because of the concurrent advances in imaging and computer technology.

01/24/2008 03:43 PM

Does early medical intervention have a role in the management of intracerebral haemorrhage

International Journal of Clinical Practice doi:10.1111/j.1742-1241.2007.01691.x

An increasing amount of research is now being directed towards the medical treatment of patients who have suffered an intracerebral haemorrhage (ICH). Despite this, no routine drug treatment to date has been shown to be unequivocally effective in unselected patients.

01/24/2008 03:39 PM

Acute limbic encephalitis - diagnostic and management implications

Australian and New Zealand Journal of Psychiatry, Volume 42, Issue 2 February 2008 , pages 166 - 169

A link between cancer and limbic encephalitis (LE) has been proposed. The aim of this case presentation is to further explore this association by literature review, inform clinicians of the investigations necessary to arrive at a diagnosis and to emphasize the clinical importance of liaison between psychiatry and other disciplines involved in management.

01/24/2008 03:38 PM

Ankylosing spondylitis and spinal cord injury: origin, incidence, management, and avoidance

Neurosurgical Focus January 2008 Volume 24, Number 1

Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease that primarily affects the vertebral column and sacroiliac joints. Over time, the disease process promotes extensive remodeling of the spinal axis via ligamentous ossification, vertebral joint fusion, osteoporosis, and kyphosis.

01/24/2008 03:35 PM

Advances in the radiosurgical treatment of large inoperable arteriovenous malformations

Neurosurgical Focus December 2007 Volume 23, Number 6

Radiosurgery has proven useful in the treatment of small arteriovenous malformations (AVMs) of the brain. However, the volume of healthy tissue irradiated around large lesions is rather significant, necessitating reduced radiation doses to avoid complications.

01/24/2008 03:34 PM

Congenital Medulloblastoma with Atypical MRI Appearance

Pediatr Neurosurg 2008;44:165-168

A 13-day-old female infant was admitted with hydrocephalus that had been diagnosed on prenatal ultrasound at 33 weeks' gestation. She was delivered by Caesarean section at 34 weeks with an Apgar score of 10.

01/24/2008 03:33 PM

Clinical Features and Treatment of Meningiomas in Children - Report of 12 Cases and Literature Review

Pediatr Neurosurg 2008;44:112-117

To study the clinical characteristics and treatment of meningiomas in children.

01/24/2008 03:31 PM

Antibiotic-Impregnated Shunt Catheters for the Treatment of Infantile Hydrocephalus

Pediatr Neurosurg 2008;44:91-96

Antibiotic-impregnated shunt (AIS) components decrease shunt infections by preventing bacterial colonization that occurs during implantation. Despite studies showing improved efficacy in preventing infection however, concern still exists regarding using AIS components in infants, especially premature ones. In this study, clinical outcomes were assessed in infants with hydrocephalus (<1 year) following AIS placement.

01/24/2008 03:30 PM

Oral valproic acid for epilepsy - long-term experience in therapy and side effects

Expert Opinion on Pharmacotherapy, Volume 9, Number 2, February 2008 , pp. 285-292(8)

Valproic acid (VPA) is considered to be a drug of first choice and one of the most frequently-prescribed antiepileptic drugs worldwide for the therapy of generalized and focal epilepsies, including special epileptic.

01/24/2008 03:29 PM

Changes in Brain Electrical Activity After Cognitive Behavioral Therapy for Posttraumatic Stress Disorder in Patients Injured in Motor Vehicle Accidents

Psychosomatic Medicine 70:13-19 (2008)

To explore changes for the first time in neural processing due to effective cognitive behavioral therapy (CBT) in posttraumatic stress disorder (PTSD) after severe motor vehicle accidents. Recent studies have highlighted the role of right hemisphere activation during withdrawal-related emotions (e.g., anxiety). There has been little research on changes in brain function due to cognitive-behavioral interventions in anxiety disorders.

01/24/2008 03:28 PM

MGMT in primary and recurrent human glioblastomas after radiation and chemotherapy and comparison with p53 status and clinical outcome

International Journal of Cancer Volume 122, Issue 6 , Pages 1391 - 1399

The data revealed a threshold of MGMT expression (30 fmol/mg protein) below which patients respond better to alkylating agents. Therefore, determination of MGMT activity in the primary tumor appears to be useful in predicting the outcome of GBM therapy.

01/24/2008 03:26 PM

Naming Is Associated with Left Temporal Pole Metabolite Levels in Neurodegenerative Diseases

Dement Geriatr Cogn Disord 2008;25:212-217

To investigate the relationship between performance in language tests and levels of brain metabolites in two selected left temporal lobe regions.

01/24/2008 03:25 PM

Bringing epilepsy out of the shadows in New Zealand

Journal of the New Zealand Medical Association, 25-January-2008, Vol 1268 No 121

Epilepsy is a common neurological disorder. Most patients with epilepsy have seizures that are relatively easily controlled, but a significant minority of patients have seizures that are resistant to standard anti-epileptic drugs.

01/24/2008 03:24 PM

Public knowledge and attitudes toward epilepsy in Kuwait

Epilepsia doi:10.1111/j.1528-1167.2007.01433.x

The study was conducted to determine the familiarity with, knowledge of, misunderstandings, and attitudes toward epilepsy among the Kuwaiti population.

01/24/2008 03:19 PM

Health resource use in epilepsy - Significant disparities by age gender and aboriginal status

Epilepsia doi:10.1111/j.1528-1167.2007.01466.x

Epilepsy imposes a significant burden on society. The objective of this study was to estimate health resource utilization (HRU) over a 1-year period in epilepsy patients, using administrative databases.

01/24/2008 03:18 PM

Tumor Angiogenic and Hypoxic Profiles Predict Radiographic Response and Survival in Malignant Astrocytoma Patients Treated With Bevacizumab and Irinotecan

Journal of Clinical Oncology, Vol 26, No 2 (January 10), 2008: pp. 271-278

The combination of a vascular endothelial growth factor (VEGF) -neutralizing antibody, bevacizumab, and irinotecan is associated with high radiographic response rates and improved survival outcomes in patients with recurrent malignant gliomas.

01/24/2008 03:17 PM

The pupil - Neuro-ophthalmology and neuro-otology

Current Opinion in Neurology. 21(1):36-42, February 2008

To give an overview on topics of pupillary function selected according to their relevance in clinical neurology. Mainly publications of the last 3 years have been considered.

01/24/2008 03:16 PM

Organizing regional stroke systems of care

Current Opinion in Neurology. 21(1):43-55, February 2008

Stroke is a major public health problem in the US and other developed countries. Stroke units reduce morbidity and mortality, and the efficacy of thrombolytic therapy propelled the development and maturation of a stroke systems of care delivery model. This model addresses the key domains in the chain of stroke survival and recovery, including primordial and primary prevention; community education; notification and response of emergency medical services; acute stroke treatment; subacute stroke treatment and secondary prevention; rehabilitation; and continuous quality improvement activities within each domain and across the system itself.

01/24/2008 03:15 PM

Ocular myasthenia - diagnostic and treatment recommendations and the evidence base

Current Opinion in Neurology. 21(1):8-15, February 2008

Increasing rigor is being applied to medical decision making, but myasthenia gravis, commonly considered the best understood autoimmune disorder from a pathophysiological basis, lags other disciplines in the evidence base used to make clinical decisions.

01/24/2008 03:13 PM

Ocular motor syndromes of the brainstem and cerebellum

Current Opinion in Neurology. 21(1):22-28, February 2008

The brainstem and cerebellum contain many neuronal types that play a critical role in eye movement control. In a physiological approach, understanding how these neuronal assemblies cooperate provides strong insight into general brain functions.

01/24/2008 03:12 PM

Interventional treatments for stroke prevention in atrial fibrillation with emphasis upon the WATCHMAN device

Current Opinion in Neurology. 21(1):64-69, February 2008

Stroke is a leading cause of death and disability worldwide. Many strokes occur in patients with atrial fibrillation. Current guidelines recommend an antithrombotic regimen with warfarin to prevent thromboembolism in atrial fibrillation; however, a substantial number of patients are not eligible for this therapy. The exclusion of the left atrial appendage from circulation seems to be an alternative strategy for stroke prevention in atrial fibrillation.

01/24/2008 03:11 PM

Intravenous paracetamol - a review of efficacy and safety in therapeutic use

Future Neurology, Volume 2, Number 6, November 2007 , pp. 673-688(16)

Paracetamol is well established as a leading nonprescription antipyretic analgesic drug and is available in oral, rectal or intravenous forms. However, except for oral paracetamol, there is a marked discrepancy between the extent to which paracetamol is used and the available evidence for an analgesic effect in postoperative pain.

01/24/2008 03:09 PM

Deep-brain stimulation

Future Neurology, Volume 2, Number 6, November 2007 , pp. 633-646(14)

Deep-brain stimulation (DBS) is a clinical intervention that has provided remarkable therapeutic benefits for otherwise treatment-resistant movement and affective disorders.

01/24/2008 03:05 PM

Blood Pressure and Antihypertensive Therapy as Predictors of Early Outcome in Acute Ischemic Stroke

Cerebrovasc Dis 2008;25:202-208

The clinical impact of blood pressure (BP) and of antihypertensive therapy (AHT) in acute ischemic stroke remains uncertain.

01/24/2008 03:04 PM

Strategies for autonomy used by people with cervical spinal cord injury - A qualitative study

Disability & Rehabilitation, Volume 30, Issue 4 2008 , pages 249 - 260

To identify strategies used by people with high cervical spinal cord injury (SCI) to function autonomously. A multidimensional concept of autonomy was used, with four dimensions: independence, self-determination, participation and identification.

01/24/2008 03:02 PM

Cognitive-behavioural stimulation protocol for severely brain-damaged patients in the post-acute stage in developmental age

Disability & Rehabilitation, Volume 30, Issue 4 2008 , pages 275 - 285

To present a cognitive-behavioural stimulation (CBS) protocol designed to help severely damaged patients in the early post-acute stage by describing the underlying methodology and assessing its efficacy compared to traditional rehabilitation methods.

01/24/2008 03:01 PM

A home-based rehabilitation program for the hemiplegic upper extremity by power-assisted functional electrical stimulation

Disability & Rehabilitation, Volume 30, Issue 4 2008 , pages 296 - 304

To assess the effects of daily power-assisted functional electrical stimulation (FES) home program therapy in chronic stroke.

01/24/2008 02:59 PM

A nursing perspective on the relationship between nursing and allied health in inpatient rehabilitation

Disability & Rehabilitation, Volume 30, Issue 4 2008 , pages 314 - 322

To generate a deeper understanding of contextual factors influencing nursing's contribution to inpatient rehabilitation units in Australia.

01/24/2008 02:58 PM

Organizing future research and intervention efforts on the impact and effects of gender differences on disability and rehabilitation - The usefulness of the International Classification of Functioning Disability and Health ICF

Disability & Rehabilitation, Volume 30, Issue 3 2008 , pages 161 - 165

The International Classification of Functioning, Disability and Health (ICF) is discussed as being relevant to research and service delivery for women with disabilities. The personal meaning a disability has for a woman is shaped largely by Personal Factors.

01/24/2008 02:57 PM

Unique aspects of women's emotional responses to disability

Disability & Rehabilitation, Volume 30, Issue 3 2008 , pages 166 - 173

To improve rehabilitation clinicians' awareness of gender differences in emotional responses to disability as a means of enhancing accuracy and sensitivity in diagnosis and treatment of persons in their care.

01/24/2008 02:55 PM

The complex array of antecedents of depression in women with physical disabilities - Implications for clinicians

Disability & Rehabilitation, Volume 30, Issue 3 2008 , pages 174 - 183

This article discusses the complex interrelation of elements of the physical, psychological, social, and environmental life context of women with physical disabilities and the association of these elements with significant disparities in rates of depression and access to mental health care for this population.

01/24/2008 02:53 PM

Women with Disabilities - Cultural competence in rehabilitation psychology

Disability & Rehabilitation, Volume 30, Issue 3 2008 , pages 184 - 190

Women with Disabilities represent a cultural group with specific issues. Rehabilitation psychologists are encouraged to familiarize themselves with some of those issues in order to deliver culturally relevant treatment. An overview is provided of psychological guidelines for attending to cultural issues in assessment, treatment, and research. Broad issues faced by Women with Disabilities are described. Disability-specific safety concerns are discussed with attention to ways in which they might be addressed by rehabilitation psychologists.

01/24/2008 02:51 PM

The spaces between - Partnerships between women researchers and Indigenous Women with disabilities

Disability & Rehabilitation, Volume 30, Issue 3 2008 , pages 191 - 201

To understand the experiences of Indigenous Australian women with chronic illnesses and disabilities and their views about a way forward in relation to partnerships in research and community-supported problem-solving.

01/24/2008 02:50 PM

Factors associated with life satisfaction in Japanese stroke outpatients

Disability & Rehabilitation, Volume 30, Issue 3 2008 , pages 222 - 230

To measure life satisfaction in Japanese stroke outpatients and randomly-sampled community residents and to investigate variables influencing their life satisfaction.

01/22/2008 09:20 PM

Analysis of progressive ophthalmic lesion in a patient with subacute sclerosing panencephalitis

Eur J Ophthalmol 2008; 18: 155 - 158

To evaluate the progressive lesions affecting the visual system in a patient with subacute sclerosing panencephalitis (SSPE).

01/22/2008 09:18 PM

The Hypodense Focus in the Petrous Apex: A Potential Pitfall on Multidetector CT Imaging of the Temporal Bone

American Journal of Neuroradiology 29:35-39, January 2008

Hypoattenuated foci in the otic capsule are routinely identified on multidetector CT (MDCT), particularly in pediatric patients. We aimed to describe and characterize the hypoattenuated focus in the anterior otic capsule.

01/22/2008 09:17 PM

Single-Center Experience of Cerecyte Coils in the Treatment of Intracranial Aneurysms: Initial Experience and Early Follow-Up Results

American Journal of Neuroradiology 29:53-56, January 2008

Endovascular treatment of intracranial aneurysms using platinum coils is effective, but uncommonly aneurysms recur. New-generation coils, such as Cerecyte, aim to address this problem. This study examines the safety and efficacy of these coils in the treatment of a cohort of ruptured and unruptured aneurysms

01/22/2008 09:12 PM

Relationship Between Aneurysm Volume and Histologic Healing after Coil Embolization in Elastase-Induced Aneurysms: A Retrospective Study

American Journal of Neuroradiology 29:98-101, January 2008

There are, to our knowledge, no histologic data correlating aneurysm volume with histologic healing following coil embolization of aneurysms. We report a retrospective study comparing histologic outcome with aneurysm volume in elastase-induced aneurysms in rabbits.

01/22/2008 09:09 PM

Preliminary Experience with Onyx Embolization for the Treatment of Intracranial Dural Arteriovenous Fistulas

American Journal of Neuroradiology 29:91-97, January 2008

Onyx was recently approved for the treatment of pial arteriovenous malformations, but its use to treat dural arteriovenous fistulas (DAVFs) is not yet well established. We now report on the treatment of intracranial DAVFs using this nonadhesive liquid embolic agent.

01/22/2008 09:07 PM

Posterior Inferior Cerebellar Artery Aneurysms: Incidence, Clinical Presentation, and Outcome of Endovascular Treatment

American Journal of Neuroradiology 29:86-90, January 2008

Results of endovascular treatment of PICA aneurysms are not well established. The purpose of this study was to report incidence, clinical presentation, and outcome of endovascular treatment in 46 patients with 47 posterior inferior cerebellar artery (PICA) aneurysms.

01/22/2008 09:04 PM

Feasibility, Procedural Morbidity and Mortality, and Long-Term Follow-Up of Endovascular Treatment of 321 Unruptured Aneurysms

American Journal of Neuroradiology 29:63-68, January 2008

The purpose of our study was to evaluate the technical feasibility, morbidity and mortality, and durability of occlusion of unruptured aneurysms treated with Guglielmi detachable coils (GDCs) with a long-term follow-up.

01/22/2008 09:03 PM

Endovascular Treatment of Intracranial Aneurysms with Matrix Detachable Coils: Midterm Anatomic Follow-Up from a Prospective Multicenter Registry

American Journal of Neuroradiology 29:57-61, January 2008

Polyglycolic/polylactic acid-covered platinum coils have been proposed to reduce the rate of aneurysm recanalization after endovascular treatment. A prospective and multicenter registry was conducted in France to evaluate the safety and short-term and midterm efficacy of Matrix coils. This analysis focused on anatomic midterm results.

01/22/2008 08:59 PM

Diagnostic Accuracy of CT Angiography with Matched Mask Bone Elimination for Detection of Intracranial Aneurysms: Comparison with Digital Subtraction Angiography and 3D Rotational Angiography

American Journal of Neuroradiology 29:134-139, January 2008

Our aim was to determine the diagnostic accuracy of multisection CT angiography combined with matched mask bone elimination (CTA-MMBE) for detection of intracranial aneurysms compared with digital subtraction angiography (DSA) and 3D rotational angiography (3DRA).

01/22/2008 08:57 PM

Reduced Purkinje Cell Number in Essential Tremor

Arch Neurol. 2008;65(1):101-107

Clinical and functional imaging evidence suggests that cerebellar dysfunction occurs in essential tremor (ET). In recent postmortem studies, we documented increased numbers of torpedoes (Purkinje cell axonal swellings) in ET patients without Lewy bodies. Purkinje cell loss, however, has never been rigorously assessed.

01/22/2008 08:53 PM

Brain Volume Decline in Aging

Arch Neurol. 2008;65(1):113-120

To assess the relation between socioeconomic status (SES) and structural brain change in nondemented older adults and to ascertain the potential role of preclinical Alzheimer disease (AD).

01/22/2008 08:50 PM

Epicrania fugax: an ultrabrief paroxysmal epicranial pain

Cephalalgia doi:10.1111/j.1468-2982.2007.01515.x

Ten patients (one man and nine women, mean age 48.8 Â± 20.1) presented with a stereotypical and undescribed type of head pain. They complaine