| 02/13/2008
03:20 PM
Treatment of pediatric epilepsy - European expert opinion 2007
Epileptic Disorders. Volume 9, Number 4, 353-412, December 2007
Childhood epilepsies are a heterogeneous group of conditions that differ in diagnostic criteria and management and have dramatically different outcomes. Despite increasing data on treatment of epilepsy, research findings on childhood epilepsy are more limited and many clinical questions remain unanswered, so that clinicians must often rely on clinical judgment.
02/13/2008
03:19 PM
Self-induced stretch syncope of adolescence - a video-EEG documentation
Epileptic Disorders. Volume 9, Number 4, 413-7, December 2007
We present the first video-EEG documentation, with ECG and EMG features, of stretch syncope of adolescence in a young, healthy 16-year-old boy. Stretch syncope of adolescence is a rarely reported, benign cause of fainting in young patients, which can be confused with epileptic seizures.
02/13/2008
03:17 PM
Desmoplastic infantile astrocytoma and characteristics of the accompanying cyst
Journal of Neurosurgery Pediatrics February 2008 Volume 1, Number 2
A desmoplastic infantile astrocytoma (DIA) is an extremely rare tumor that comprises a solid astrocytic tumor accompanied by a large cyst and involves the superficial cerebral cortex and leptomeninges in infants.
02/13/2008
03:14 PM
Delayed Homicides Due to Infant Head Injury Initially Reported as Natural - Cerebral Palsy - Deaths
Pediatric and Developmental Pathology Volume 11, Issue 1 (January-February 2008) pp. 39-45
A spectrum of neuropathology occurs in infants who sustain traumatic brain injury. Because of a prolonged survival interval, there is a risk that these deaths may not be recognized as a sequel of trauma.
02/13/2008
03:13 PM
A Prospective Controlled Study in the Prevalence of Posttraumatic Headache Following Mild Traumatic Brain Injury
Pain Medicine doi:10.1111/j.1526-4637.2007.00404.x
To establish the prevalence of post traumatic headache, persisting at 3 months following minor traumatic brain injury.
02/13/2008
03:11 PM
Think to Move - a Neuromagnetic Brain-Computer Interface BCI System for Chronic Stroke
Stroke doi: 10.1161/STROKEAHA.107.505313
Stroke is a leading cause of long-term motor disability among adults. Present rehabilitative interventions are largely unsuccessful in improving the most severe cases of motor impairment, particularly in relation to hand function.
02/13/2008
03:10 PM
Regional White Matter Pathology in Mild Cognitive Impairment. Differential Influence of Lesion Type on Neuropsychological Functioning
Stroke doi: 10.1161/STROKEAHA.107.502534
Associations between regional white matter lesion pathology and neuropsychological performance across the aging spectrum are not well understood and, to date, research has been largely contradictory and inconclusive.
02/13/2008
03:09 PM
Independent Cognitive Effects of Atrophy and Diffuse Subcortical and Thalamico-Cortical Cerebrovascular Disease in Dementia
Stroke doi: 10.1161/STROKEAHA.107.491936
Brain atrophy, cortical infarction, and subcortical ischemic vasculopathy have all been associated with cognitive dysfunction. The interrelationships between these pathologies and their independent contributions to cognitive function remain unclear.
02/13/2008
03:08 PM
Impact of Restricting Enrollment in Stroke Genetics Research to Adults Able to Provide Informed Consent
Sttoke doi: 10.1161/STROKEAHA.107.494518
The extent of potential consent bias in observational studies elucidating genetic and environmental contributions to ischemic stroke is largely unknown. The purpose of this study was to assess differences in stroke cohort characteristics between those who provided informed consent and those whose enrollment was authorized by surrogate decision makers
02/13/2008
03:07 PM
Histological Characterization of Restenotic Carotid Plaques in Relation to Recurrence Interval and Clinical Presentation - A Cohort Study
Stroke doi: 10.1161/STROKEAHA.107.496703
Restenosis is an important complication after carotid endarterectomy, but little is known about plaque composition in early versus late restenosis and which plaque characteristics are associated with symptomatic clinical presentation of restenotic lesions.
02/13/2008
03:06 PM
Gray Matter Atrophy in Patients With Ischemic Stroke With Cognitive Impairment
Stroke doi: 10.1161/STROKEAHA.107.507392
Patients with ischemic stroke are at risk for developing vascular cognitive impairment ranging from mild impairments to dementia. MRI findings of infarction, white matter hyperintensities, and global cerebral atrophy have been implicated in the development of vascular cognitive impairment.
02/13/2008
03:05 PM
Genetics of Intracranial Aneurysms
Stroke doi: 10.1161/STROKEAHA.107.497305
Genetic determinants probably play a role in the development of intracranial aneurysms. We review the present knowledge on this issue.
02/13/2008
03:04 PM
Endovascular Treatment of Unruptured Intracranial Aneurysms With Guglielmi Detachable Coils - Short- and Long-Term Results of a Single-Centre Series
Stroke doi: 10.1161/STROKEAHA.107.496372
Purpose of the present study is to evaluate the clinical outcome of endovascular treatment of unruptured intracranial aneurysms and to address the question of long-term stability and protection against future subarachnoid hemorrhage.
02/13/2008
03:03 PM
Delayed Treatment With Minocycline Ameliorates Neurologic Impairment Through Activated Microglia Expressing a High-Mobility Group Box1-Inhibiting Mechanism
Stroke doi: 10.1161/STROKEAHA.107.495820
Minocycline, a semisynthetic tetracycline antibiotic, has been reported to ameliorate brain injury and inhibit microglial activation after focal cerebral ischemia. However, the cerebroprotective mechanism of minocycline remains unclear.
02/13/2008
03:01 PM
Effects of Nebicapone on Levodopa Pharmacokinetics Catechol-O-methyltransferase Activity, and Motor Fluctuations in Patients with Parkinson Disease
Clinical Neuropharmacology. 31(1):2-18, January/February 2008
To investigate the effects of nebicapone, a new catechol-O-methyltransferase (COMT) inhibitor, on levodopa pharmacokinetics, COMT activity, and motor fluctuations in Parkinson disease in comparison to placebo and entacapone.
02/13/2008
03:00 PM
Clinical evaluation of attentional processes in children with benign childhood epilepsy with centrotemporal spikes BCECTS
Epileptic Disorders. Volume 9, Number 4, 424-31, December 2007
The aim of this study was to identify the attentional processes specifically affected in children with benign childhood epilepsy with centrotemporal spikes (BCECTS). The impact of several factors - laterality of discharges, age-at-onset and duration of epilepsy, and medication - on these cognitive functions was also studied.
02/13/2008
02:59 PM
Statin Therapy for Stroke Prevention
Stroke doi: 10.1161/STROKEAHA.107.501361
Statins are widely used to reduce the risk of stroke in patients with coronary artery disease (CAD), but less so in patients without CAD. We reviewed recent trials for new evidence for the reduction in risk of stroke.
02/13/2008
02:58 PM
Nonaspirin Nonsteroidal Anti-inflammatory Drugs and Hemorrhagic Stroke Risk - The Acute Brain Bleeding Analysis Study
Stroke doi: 10.1161/STROKEAHA.107.497040
The relationship between nonaspirin nonsteroidal anti-inflammatory drugs (NANSAIDs) and hemorrhagic stroke (HS) remains unclear. We examined the risk of HS associated with the use of NANSAIDs in Koreans.
02/13/2008
02:57 PM
MRI Detection of Early Blood-Brain Barrier Disruption. Parenchymal Enhancement Predicts Focal Hemorrhagic Transformation After Thrombolysis
Stroke doi: 10.1161/STROKEAHA.107.497719
Blood-brain barrier disruption may be a predictor of hemorrhagic transformation (HT) in ischemic stroke. We hypothesize that parenchymal enhancement (PE) on postcontrast T1-weighted MRI predicts and localizes subsequent HT.
02/13/2008
02:56 PM
Linking MRI Hyperintensities With Patterns of Neuropsychological Impairment. Evidence for a Threshold Effect
Stroke doi: 10.1161/STROKEAHA.107.489997
Leukoaraiosis (LA) might interrupt intra- and interhemispheric communication and thus induce cognitive impairments and dementia. It remains unclear, however, if there is a volume threshold of LA that is needed before either the signs of dementia and/or a specific pattern of neuropsychological impairment become manifest.
02/13/2008
02:55 PM
How Reliable Is Perfusion MR in Acute Stroke - Validation and Determination of the Penumbra Threshold Against Quantitative PET
Stroke doi: 10.1161/STROKEAHA.107.500090
Perfusion magnetic resonance imaging (pMR) is increasingly used in acute stroke, but its physiologic significance is still debated. A reasonably good correlation between pMR and positron emission tomography (PET) has been reported in normal subjects and chronic cerebrovascular disease, but corresponding validation in acute stroke is still lacking.
02/13/2008
02:53 PM
Diagnostic Criteria of Vascular Dementia in CADASIL
Stroke doi: 10.1161/STROKEAHA.107.490672
Subcortical ischemic vascular dementia (SIVD) is a major subtype of vascular dementia (VaD). Recently, the diagnostic criteria of VaD have been modified to encompass this entity. Application of these criteria in CADASIL, a genetic model of SIVD, may help to better assess their significance. The aim of this study was to compare different sets of diagnostic criteria of VaD in a population of CADASIL patients.
02/13/2008
02:50 PM
Magnetic Resonance MR Patterns of Brain Metastasis in Lung Cancer Patients - Correlation of Imaging Findings with Symptom
Journal of Thoracic Oncology. 3(2):140-144, February 2008
Asymptomatic brain metastasis in lung cancer patients, if detected early have been reported to show survival benefit with treatment. These asymptomatic metastasis have been found to be smaller and less in number than those with symptoms.
02/13/2008
02:48 PM
Paraplegia after extensive thoracic and thoracoabdominal aortic aneurysm repair - Does critical spinal cord ischemia occur postoperatively
J Thorac Cardiovasc Surg 2008;135:324-330
Spinal cord injury can occur not only during extensive thoracoabdominal aneurysm repair but also postoperatively, causing delayed-onset paraplegia.
02/13/2008
02:46 PM
Spontaneous Drainage of Neonatal Cephalohematoma - A Delayed Complication of Scalp Abscess
Clinical Pediatrics, Vol. 47, No. 2, 183-185 (2008)
Neonatal cephalohematomas are known complications of traumatic deliveries, and the majority of cases resolve without intervention. Scalp abscesses are rare and often described as benign complications of fetal scalp monitoring.
02/13/2008
02:44 PM
Higher Stroke Incidence in the Spring Season Regardless of Conventional Risk Factors - Takashima Stroke Registry Japan, 1988-2001
Stroke doi: 10.1161/STROKEAHA.107.495929
Seasonal variation in stroke incidence was examined using 14-year stroke registration data in a Japanese population. We also examined if this variation was modified by conventional stroke risk factors hypertension, diabetes mellitus, drinking, and smoking.
02/13/2008
02:42 PM
Systemic infections after acute stroke
Aging Health, Volume 4, Number 1, February 2008 , pp. 85-94(10)
After an acute stroke, systemic infection can complicate the recovery process and lead to a worse clinical outcome, including a higher risk of mortality.
02/13/2008
02:41 PM
Bone health and antiseizure drugs - diagnosis and management
Aging Health, Volume 4, Number 1, February 2008 , pp. 75-84(10)
There is growing evidence for the association of antiepileptic medications (AEDs) and bone disease. Increased rates of vitamin D deficiency, elevated laboratory markers of bone turnover and increased rates of osteopenia, osteomalacia and fracture have all been reported.
02/13/2008
02:39 PM
White matter angiopathy is common in pediatric patients with intractable focal epilepsies
Epilepsia doi:10.1111/j.1528-1167.2007.01514.x
The blood-brain barrier (BBB) and functional organization of blood vessels is severely affected in many epilepsy disorders. This was repetitively shown with respect to the cause, effect and treatment of seizures.
02/13/2008
02:38 PM
The three stages of epilepsy in patients with CDKL5 mutations
Epilepsia doi:10.1111/j.1528-1167.2007.01520.x
Mutations in the X-linked cyclin-dependent kinase-like 5 (CDKL5) gene are responsible for a severe encephalopathy with early epilepsy.
02/13/2008
02:37 PM
Regional neocortical thinning in mesial temporal lobe epilepsy
Epilepsia doi:10.1111/j.1528-1167.2008.01539.x
To determine the nature and extent of regional cortical thinning in patients with mesial temporal lobe epilepsy (MTLE).
02/13/2008
02:36 PM
Mitochondrial respiratory chain defects: Underlying etiology in various epileptic conditions
Epilepsia doi:10.1111/j.1528-1167.2007.01522.x
To determine if defects in mitochondrial respiratory chain enzyme complexes (MRCs) contribute to the etiology of childhood epilepsy.
02/13/2008
02:35 PM
Leucoencephalopathy with vanishing white matter may cause progressive myoclonus epilepsy
Epilepsia doi:10.1111/j.1528-1167.2008.01542.x
Leucoencephalopathy with vanishing white matter (VWM) is caused by mutations in the genes encoding for one of the five subunits that constitute the eukaryotic initiation factor 2B (eIF2B), and is characterized by a highly suggestive MRI pattern indicating vanishing of the cerebral white matter.
02/13/2008
02:24 PM
Epilepsy surgery in patients with normal or nonfocal MRI scans - Integrative strategies offer long-term seizure relief
Epilepsia doi:10.1111/j.1528-1167.2007.01428.x
Excisional surgery achieves seizure freedom in a large proportion of children with intractable lesional epilepsy, but the outcome for children without a focal lesion on MRI is less clear. We report the outcome of a cohort predominantly of children with nonlesional intractable partial epilepsy undergoing resective surgery.
02/13/2008
02:22 PM
Balloon cells and dysmorphic neurons in the hippocampus associated with epileptic amnesic syndrome - A case report
Epilepsia doi:10.1111/j.1528-1167.2007.01527.x
Recently, we encountered a 39-year-old woman with typical epileptic amnesic syndrome. The patient underwent right anterior temporal lobectomy, which removed the right hippocampus.
02/13/2008
02:21 PM
An autosomal dominant genetically heterogeneous variant of rolandic epilepsy and speech disorder
Epilepsia doi:10.1111/j.1528-1167.2007.01517.x
We report a three generation pedigree with 11 of 22 affected with a variant form of rolandic epilepsy, speech impairment, oromotor apraxia, and cognitive deficit. The core features comprised nocturnal rolandic seizures, interictal centrotemporal spike waves with early age of onset and late age of offset.
02/13/2008
02:19 PM
Abnormal Diffusion-Weighted Imaging Findings in an Adult Patient With Acute Cerebellitis Presenting With a Normal Magnetic Resonance Imaging
Journal of Computer Assisted Tomography. 32(1):156-158, January/February 2008
Acute cerebellitis is an unusual central nervous system complication of infectious disease often due to viral etiology. Diagnosis is aided by neuroimaging studies, actually by magnetic resonance imaging in the first place, which shows increased signal intensity on T2-weighted images.
02/13/2008
02:17 PM
Neuronal plasticity - implications in epilepsy progression and management
Drug Development Research Volume 68, Issue 8 , Pages 498 - 511
Epilepsy is a common neurological disease. A growing number of research studies provide evidence regarding the progressive neuronal damage induced by prolonged seizures or status epilepticus (SE), as well as recurrent brief seizures. Importantly, seizure is only one aspect of epilepsy. However, cognitive and behavioral deficits induced by progressive seizures or antiepileptic treatment can be detrimental to individual function.
02/13/2008
02:15 PM
Insulin-related decrease in cerebral glucose despite normoglycemia in aneurysmal subarachnoid hemorrhage
Critical Care 2008, 12:R9
Hyperglycaemia following aneurysmal subarachnoid hemorrhage (SAH) is associated with complications and impaired neurological recovery. The aim of this study was to determine the effect of insulin treatment for glucose control on cerebral metabolism in SAH patients.
02/13/2008
02:14 PM
Effects of levetiracetam on EEG abnormalities in juvenile myoclonic epilepsy
Epilepsia doi:10.1111/j.1528-1167.2007.01523.x
A multicenter, prospective, long-term, open-label study to evaluate the effects of levetiracetam on electroencephalogram (EEG) abnormalities and photoparoxysmal response (PPR) of patients affected by juvenile myoclonic epilepsy (JME).
02/13/2008
02:13 PM
Cortical auditory dysfunction in benign rolandic epilepsy
Epilepsia doi:10.1111/j.1528-1167.2007.01519.x
To evaluate cortical auditory function, including speech recognition, in children with benign rolandic epilepsy (BRE).
02/13/2008
02:09 PM
Circalunar and ultralunar periodicities in women with partial seizures
Epilepsia doi:10.1111/j.1528-1167.2008.01537.x
Little consensus exists for the definition of catamenial epilepsy. Few studies have evaluated the periodicity of seizures to test the hypothesis that seizures in women have periodic patterns of occurrence independent of a priori hormonal considerations. In the present study, we determined seizure periodicity according to a "menstrual clock" provided by a common phase marker of the onset of menses.
02/13/2008
02:03 PM
A practical overview of tizanidine use for spasticity secondary to multiple sclerosis stroke and spinal cord injury
Current Medical Research and Opinion, Volume 24, Number 2, February 2008 , pp. 425-439(15)
An unfiltered literature search of the term 'tizanidine' was undertaken on the Medline database resulting in 311 papers. As the review focused on tizanidine clinical pharmacokinetics, efficacy, and tolerability, with comparisons limited to the oral antispastic agents baclofen, diazepam, and dantrolene, 53 articles were selected for detailed assessment.
02/13/2008
01:54 PM
Altered innate immunity following spinal cord injury
Spinal Cord 12 February 2008
To replicate the finding of impaired immunocyte function following spinal cord injury (SCI). To determine whether cellular immune function in SCI subjects with decentralized sympathetic nervous system (SNS) (T6 and above) varies from SCI subjects with intact SNS (below T6).
02/13/2008
01:53 PM
THE PRESENCE OF MULTIPLE MICROBLEEDS AS A PREDICTOR OF SUBSEQUENT CEREBRAL HEMORRHAGE IN PATIENTS WITH MOYAMOYA DISEASE
Neurosurgery. 62(1):104-112, January 2008
To examine the relationship between asymptomatic microbleeds (MBs) and the occurrence of subsequent stroke in patients with moyamoya disease.
02/13/2008
01:51 PM
THE NATIONAL FOOTBALL LEAGUE - CEREBRAL CONCUSSION, PEER-REVIEW AND THE OATH OF HIPPOCRATES - KEYNOTE ADDRESS - NFL Concussion Summit, Chicago 2007
Neurosurgery. 62(1):202-203, January 2008
The following comments convey the assembled keynote points made at a summit called by Commissioner Roger Goodell involving all leading medical personnel in the National Football League, outside experts and players union representatives.
02/13/2008
01:50 PM
THE IMPACT OF MICROSURGICAL FENESTRATION OF THE LAMINA TERMINALIS ON SHUNT-DEPENDENT HYDROCEPHALUS AND VASOSPASM AFTER ANEURYSMAL SUBARACHNOID HEMORRHAGE
Neurosurgery. 62(1):123-134, January 2008
Chronic hydrocephalus requiring shunt placement and cerebral vasospasm are common complications after aneurysmal subarachnoid hemorrhage. Recent publications have investigated the possibility that microsurgical fenestration of the lamina terminalis during aneurysm surgery may reduce the incidence of shunt-dependent hydrocephalus and cerebral vasospasm.
02/13/2008
01:49 PM
TARGETING THE alpha 1 SUBUNIT OF THE SODIUM PUMP TO COMBAT GLIOBLASTOMA CELLS
Neurosurgery. 62(1):211-222, January 2008
Ion transporters play pivotal roles in cancer cell migration in general and in glioblastomas (GBMs) in particular. However, the specific role of Na+/K+-ATPase (the sodium pump) and, in particular, its [alpha]1 subunit, has remained unexplored in GBMs.
02/13/2008
01:48 PM
REVERSIBLE NEUROLOGICAL SYMPTOMS CAUSED BY DIATHERMY IN A PATIENT WITH DEEP BRAIN STIMULATORS - CASE REPORT
Neurosurgery. 62(1):E256, January 2008
Diathermy is contraindicated in patients with implanted deep brain stimulation (DBS) electrodes. As the clinical applications for diathermy and the number of patients with DBS implants continue to grow, the opportunity for diathermy-induced complications in the population with DBS electrodes increases.
02/13/2008
01:47 PM
RECURRENT SUBARACHNOID HEMORRHAGE CAUSED BY A DE NOVO BASILAR TIP ANEURYSM DEVELOPING WITHIN 8 WEEKS AFTER CLIPPING OF A RUPTURED ANTERIOR COMMUNICATING ARTERY ANEURYSM - CASE REPORT
Neurosurgery. 62(1):E259-E260, January 2008
Well-documented case reports of the rapid formation and rupture of de novo aneurysms of the posterior circulation are rare.
02/13/2008
01:46 PM
RADIOSURGERY AS DEFINITIVE MANAGEMENT OF INTRACRANIAL MENINGIOMAS
Neurosurgery. 62(1):53-60, January 2008
Stereotactic radiosurgery has become an important primary or adjuvant minimally invasive management strategy for patients with intracranial meningiomas with the goals of long-term tumor growth prevention and maintenance of patient neurological function. We evaluated clinical and imaging outcomes of meningiomas stratified by histological tumor grade.
02/13/2008
01:44 PM
NEUROSURGERY IN THE REALM OF 10-9 PART 1 - STARDUST AND NANOTECHNOLOGY IN NEUROSCIENCE
Neurosurgery. 62(1):1-20, January 2008
NANOTECHNOLOGY AS A science has evolved from notions and speculation to emerge as a prominent combination of science and engineering that stands to impact innumerable aspects of technology.
02/13/2008
01:43 PM
LONG-TERM EXPANSION OF ADULT HUMAN BRAIN SUBVENTRICULAR ZONE PRECURSORS
Neurosurgery. 62(1):223-231, January 2008
Many common neurosurgical procedures, including anterior temporal lobectomy and endoscopic ventricular puncture, allow neurosurgeons to retrieve portions of the germinal subventricular zone (SVZ).
02/13/2008
01:42 PM
INTRA-ABDOMINAL PRESSURE - THE NEGLECTED VARIABLE IN SELECTING THE VENTRICULOPERITONEAL SHUNT FOR TREATING HYDROCEPHALUS
Neurosurgery. 62(1):143-150, January 2008
In the selection of a ventriculoperitoneal cerebrospinal fluid shunt, the intra-abdominal pressure (IAP) is traditionally neglected as a result of the idea that its value is close to 0 mmHg. Our aim was to explore the relationship between body mass index (BMI) and IAP with the goal of providing clinically relevant data that could help neurosurgeons to estimate IAP and select the appropriate shunt for patients with hydrocephalus and especially those with normal-pressure hydrocephalus syndrome.
02/13/2008
01:41 PM
IMPROVEMENT AFTER CEREBROSPINAL FLUID DRAINAGE IS RELATED TO LEVELS OF N-ACETYL-ASPARTATE IN IDIOPATHIC NORMAL PRESSURE HYDROCEPHALUS
Neurosurgery. 62(1):135-142, January 2008
This study uses proton magnetic resonance spectroscopy to investigate whether or not idiopathic normal pressure hydrocephalus is associated with neuronal dysfunction or ischemia in the brain. We evaluate whether or not proton magnetic resonance spectroscopy is useful for predicting improvement after long-term external lumbar drainage (ELD) of cerebrospinal fluid.
02/13/2008
01:40 PM
IMPACT OF NOSOCOMIAL INFECTIOUS COMPLICATIONS AFTER SUBARACHNOID HEMORRHAGE
Neurosurgery. 62(1):80-87, January 2008
Critically ill neurological patients are susceptible to infections that may be distinct from other intensive care patients. The aim of this study is to quantify the prevalence, risk factors, and effect on the outcome of nosocomial infectious complications in patients with subarachnoid hemorrhage (SAH).
02/13/2008
01:39 PM
GUIDELINES FOR THE SURGICAL TREATMENT OF UNRUPTURED INTRACRANIAL ANEURYSMS - THE FIRST ANNUAL J. LAWRENCE POOL MEMORIAL RESEARCH SYMPOSIUM-CONTROVERSIES IN THE MANAGEMENT OF CEREBRAL ANEURYSMS
Neurosurgery. 62(1):183-194, January 2008
THE MANAGEMENT OF unruptured cerebral aneurysms remains one of the most controversial topics in neurosurgery.
02/13/2008
01:36 PM
EFFECTS OF DEFEROXAMINE-ACTIVATED HYPOXIA-INDUCIBLE FACTOR-1 ON THE BRAINSTEM AFTER SUBARACHNOID HEMORRHAGE IN RATS
Neurosurgery. 62(1):232-241, January 2008
Hypoxia-inducible factor (HIF)-1 is a transcription factor that regulates the expression of various neuroprotective genes. The goal of this study was to clarify the relationship between HIF-1 expression and subarachnoid hemorrhage (SAH) and to characterize the effects of deferoxamine (DFO)-induced increases in HIF-1 protein levels on the brainstem and the basilar artery (BA) after experimental SAH.
02/13/2008
01:34 PM
DIFFUSION TENSOR TRACTOGRAPHY PREDICTS MOTOR FUNCTIONAL OUTCOME IN PATIENTS WITH SPONTANEOUS INTRACEREBRAL HEMORRHAGE
Neurosurgery. 62(1):97-103, January 2008
We prospectively investigated the predictive value of diffusion tensor tractography for motor functional outcome in a case series of patients with intracerebral hemorrhage.
02/13/2008
01:33 PM
CORRESPONDENCE OF TUMOR LOCALIZATION WITH TUMOR RECURRENCE AND CYTOGENETIC PROGRESSION IN MENINGIOMAS
Neurosurgery. 62(1):61-70, January 2008
Meningiomas are mostly benign tumors that originate from the coverings of the brain and spinal cord. Cytogenetically, they reveal a normal karyotype or, typically, monosomy of chromosome 22.
02/13/2008
01:32 PM
CHANGES IN EXTRACELLULAR CONCENTRATIONS OF SOME CYTOKINES CHEMOKINES AND NEUROTROPHIC FACTORS AFTER INSERTION OF INTRACEREBRAL MICRODIALYSIS CATHETERS IN NEUROSURGICAL PATIENTS
Neurosurgery. 62(1):151-158, January 2008
The extracellular levels of eight different inflammatory agents were analyzed during the initial 36 hours after insertion of microdialysis catheters in patients.
02/13/2008
01:31 PM
ANGIOGENESIS AND GLIOMAS - CURRENT ISSUES AND DEVELOPMENT OF SURROGATE MARKERS
Neurosurgery. 62(1):31-52, January 2008
DESPITE SIGNIFICANT IMPROVEMENTS, current therapies have yet to cure infiltrative gliomas. Glioma progression is strongly dependent on the development of a new vascular network that occurs primarily by angiogenesis.
02/13/2008
01:25 PM
ACCURACY OF 16-ROW MULTISLICE COMPUTED TOMOGRAPHIC ANGIOGRAPHY FOR ASSESSMENT OF SMALL CEREBRAL ANEURYSMS
Neurosurgery. 62(1):113-122, January 2008
Many cases of subarachnoid hemorrhage are the result of rupture of small cerebral aneurysms. The aim of the study was to assess the diagnostic accuracy of 16-row multislice computed tomographic angiography (CTA) in detecting small cerebral aneurysms (<=5 mm) compared with digital subtraction angiography (DSA), surgical findings, or both.
02/13/2008
01:24 PM
Simple partial frontal status epilepticus with recurrent asymmetric tonic seizures
NEUROLOGY 2008;70:e30-31
A 44-year-old man with antecedents of mental retardation, diffuse right cerebral atrophy, and complex partial seizures with and without secondary generalization was admitted to our hospital for reevaluation of his antiepileptic medication.
02/13/2008
01:23 PM
Cerebral T-waves from an aneurysmal cardunculus compression
NEUROLOGY 2008;70:e28-29
A 41-year-old woman developed temporary substernal chest pain. Physical examination was normal.
02/13/2008
01:21 PM
Prevalence of SOD1 mutations in the Italian ALS population
Five to 10% of amyotrophic lateral sclerosis (ALS) cases are reported to be familial (FALS), and mutations of SOD1 account for 20% of these cases. However, estimates of SOD1 mutation prevalence have been exclusively based on case series and clinic referral cohorts.
02/13/2008
01:20 PM
Limbic encephalitis - An expanding concept
Neurology.2008; 70: 500-501
02/13/2008
01:19 PM
Ischemic bilateral hippocampal dysfunction during transient global amnesia
Neurology.2008; 70: 580-581
02/13/2008
01:18 PM
Evaluation of corticospinal tracts in ALS with diffusion tensor MRI and brainstem stimulation
NEUROLOGY 2008;70:528-532
To assess corticospinal tract involvement in patients with amyotrophic lateral sclerosis (ALS) by correlating diffusion tensor imaging (DTI) measures with intra- and extracranial central motor conduction time (CMCT) and clinical features of the patients.
02/13/2008
01:17 PM
Corticobasal syndrome and primary progressive aphasia as manifestations of LRRK2 gene mutations
NEUROLOGY 2008;70:521-527
Mutations in the LRRK2 gene are an important cause of familial and nonfamilial parkinsonism. Despite pleomorphic pathology, LRRK2 mutations are believed to manifest clinically as typical Parkinson disease (PD). However, most genetic screens have been limited to PD clinic populations.
02/13/2008
01:16 PM
ACUTE STROKE - BENCH TO BEDSIDE
Neurology.2008; 70: 582
02/13/2008
01:15 PM
Anti-NMDA receptor encephalitis in Japan
NEUROLOGY 2008;70:504-511
To report the definitive diagnosis of anti-NMDA receptor (NMDAR) encephalitis in four Japanese women previously diagnosed with "juvenile acute nonherpetic encephalitis" of unclear etiology, and to describe their long-term follow-up in the absence of tumor resection.
02/13/2008
01:14 PM
Status Epilepticus Without an Underlying Cause and Risk of Death
Arch Neurol. 2008;65(2):221-224
Retrospective cohort study. The increased risk of death after SE has been largely ascribed to the underlying medical condition. It is unknown whether SE itself affects risk of death. We address this question by studying idiopathic/cryptogenic SE.
02/13/2008
01:12 PM
Increased Frequency of Learning Disability in Patients With Primary Progressive Aphasia and Their First-Degree Relatives
Arch Neurol. 2008;65(2):244-248
To demonstrate that learning disabilities (LDs) are more common in patients with PPA and their first-degree family members.
02/13/2008
01:12 PM
Combined Immunomodulatory Therapy in Autoimmune Autonomic Ganglionopathy
Arch Neurol. 2008;65(2):213-217
Autoimmune autonomic ganglionopathy is a disorder defined by antibodies to the nicotinic acetylcholine receptor of the autonomic ganglia. Patients present with symptoms of autonomic failure, including syncope, orthostatic hypotension, bowel and bladder hypomotility, pupillary dysfunction, and dry mouth and eyes.
02/13/2008
01:10 PM
Clinical Spectrum of Reversible Posterior Leukoencephalopathy Syndrome
Arch Neurol. 2008;65(2):205-210
Reversible posterior leukoencephalopathy syndrome (RPLS) is characterized by neuroimaging findings of reversible vasogenic subcortical edema without infarction. The clinical syndrome of RPLS typically involves headache, encephalopathy, visual symptoms, and seizures.
02/13/2008
01:09 PM
Acute Disseminating Encephalomyelitis in Neuromyelitis Optica
Arch Neurol. 2008;65(2):267-271
To report the clinical and radiological features of 2 patients with neuromyelitis optica (NMO) associated with severe acute disseminating encephalomyelitis.
02/13/2008
01:08 PM
Stereotactic Radiosurgery for Treatment of Epilepsy
Arch Neurol. 2008;65(2):177-183
Stereotactic radiosurgery, known for efficacy in the noninvasive treatment of tumors or arteriovenous malformations that are otherwise difficult to access through traditional surgery, is an emerging technology in the treatment of focal epileptic lesions.
02/13/2008
01:07 PM
Protein Misfolding and Neurodegeneration
Arch Neurol. 2008;65(2):184-189
A key molecular pathway implicated in diverse neurodegenerative diseases is the misfolding, aggregation, and accumulation of proteins in the brain. Compelling evidence strongly supports the hypothesis that accumulation of misfolded proteins leads to synaptic dysfunction, neuronal apoptosis, brain damage, and disease.
02/13/2008
01:06 PM
Restricted Diffusion on Magnetic Resonance Imaging in Partial Status Epilepticus
Arch Neurol. 2008;65(2):278-279
An 82-year-old woman with hypertension and bipolar disorder was admitted with new-onset generalized tonic-clonic seizures. On admission, magnetic resonance imaging (MRI) results were normal and electroencephalography showed right posterior quadrant slowing.
02/13/2008
12:50 PM
Cysticercotic Encephalitis - Case Report of Miliary Infestation in an Encephalopathic Fashion
Arch Neurol. 2008;65(2):276-277
A 40-year-old woman was admitted to the emergency department with a history of frontal headache, no quantified fever, and a decreasing level of consciousness for the last 4 months. Neurological examination showed sleepiness, inattention, and disorientation. She did not have cranial nerve dysfunction or focal signs.
|
What
is RSS?
