The guglielmi detachable coil 'crescent' in the endovascular treatment of peripheral brain aneurysms - technical case report
Neurosurgery. 61(5) Operative Neurosurgery Supplement 2:E295-E296, November 2007
Peripheral brain aneurysms arise from the distal segments of cerebral arteries. They can be treated by surgery or by an endovascular approach. We present our experience of endovascular treatment of peripheral brain aneurysms with a novel endovascular device, the Guglielmi detachable coil
(GDC) "crescent."
12/28/2007
02:58 PM
Extended transsphenoidal approach to anterior communicating artery aneurysm: aneurysm incidentally identified during macroadenoma resection - technical case report
Neurosurgery. 61(5) Operative Neurosurgery Supplement 2:E299-E300, November 2007
Full exposure of an aneurysm and surrounding structures with minimal brain retraction is important to eliminate the aneurysm safely and accurately. We describe an extended transsphenoidal approach for clipping an anterior communicating artery
(ACoA) aneurysm.
12/28/2007
02:57 PM
Endoarterial management of dural arteriovenous malformations with isolated sinus using onyx-18 - technical case report
Neurosurgery. 61(5) Operative Neurosurgery Supplement 2:E293-E294, November 2007
Anatomic and clinical cure of dural arteriovenous malformations (DAVM) with isolated sinus is difficult to achieve by endovascular means without previous surgical exposure. We propose a new management technique using a new liquid embolic agent (ethylene-vinyl alcohol copolymer [Onyx-18]; ev3 Inc., Plymouth, MN) via an endoarterial approach that would avoid surgical craniotomy.
12/28/2007
02:56 PM
Double origin of the posteroinferior cerebellar artery - angiographic anatomy and endovascular treatment of concurrent vertebrobasilar dissection
Neurosurgery. 61(5) Operative Neurosurgery Supplement 2:242-248, November 2007
The aim of this study was to evaluate the anatomic details and therapeutic implications of the double origin of the posteroinferior cerebellar artery
(DOPICA).
12/28/2007
02:51 PM
Extended endoscopic transsphenoidal approach for tuberculum sellae meningiomas
Neurosurgery. 61(5) Operative Neurosurgery Supplement 2:229-238, November 2007
sellae meningiomas are classically removed through several different surgical transcranial approaches, including the pterional transsylvian route. Recently, the indications for the transsphenoidal technique, traditionally proposed only for the treatment of intrasellar lesions, have been extended to include lesions located in the supra- and parasellar areas and, among them, tuberculum sellae
meningiomas.
12/28/2007
02:50 PM
Stent reconstruction of wide-necked aneurysms across the circle of willis
Neurosurgery. 61(5) Operative Neurosurgery Supplement 2:249-255, November 2007
To describe a novel technique for single stent reconstruction of wide-necked aneurysms arising from the circle of Willis.
12/28/2007
02:49 PM
The minipterional craniotomy - technical description and anatomic assessment
Neurosurgery. 61(5) Operative Neurosurgery Supplement 2:256-265, November 2007
To describe a modification of the pterional approach (PT), the minipterional craniotomy
(MPT), and compare the anatomic exposure provided by these two approaches.
12/28/2007
02:47 PM
Microsurgical management of anterior communicating artery aneurysms
Neurosurgery. 61(5) Operative Neurosurgery Supplement 2:273-292, November 2007
Aneurysms of the anterior communicating (ACOM) artery are the most frequently occurring type of ruptured intracranial aneurysms. The peculiar anatomy of the anterior communicating artery complex, its anatomic variations, and its multiple perforators, along with the deep location of these aneurysms and our difficulty accessing them, pose challenging anatomic problems in their surgical treatment.
12/28/2007
02:45 PM
Minimally invasive insertion of syringosubarachnoid shunt for posttraumatic syringomyelia - technical case report
Neurosurgery. 61(5) Operative Neurosurgery Supplement 2:E331-E332, November 2007
Symptomatic posttraumatic syringomyelia affects up to 10% of patients with spinal cord injuries and manifests in a delayed manner as progressive sensorimotor changes below the level of the
syrinx.
12/28/2007
02:44 PM
Coregistration of digital photography of the human cortex and cranial magnetic resonance imaging for visualization of subdural electrodes in epilepsy surgery
Neurosurgery. 61(5) Operative Neurosurgery Supplement 2:340-345, November 2007
To develop a method for the coregistration of digital photographs of the human cortex with head magnetic resonance imaging
(MRI) scans for invasive diagnostics and resective neocortical epilepsy surgery.
12/28/2007
02:43 PM
Refinement of the extradural anterior clinoidectomy - surgical anatomy of the orbitotemporal periosteal fold
Neurosurgery. 61(5) Operative Neurosurgery Supplement 2:179-186, November 2007
Extradural removal of the anterior clinoid process is technically challenging because of the limited exposure. In our study of the extradural anterior
clinoidectomy, we describe anatomic details and landmarks to facilitate sectioning of the orbitotemporal periosteal fold and elevation of the temporal fossa dura from the superior orbital fissure.
12/28/2007
02:42 PM
Performance of a new type of suction tip attachment during intramedullary tumor dissection - technical note
Neurosurgery. 61(5) Operative Neurosurgery Supplement 2:E241, November 2007
We describe an innovative 1.7-mm-diameter, latex-free aspirator tip attachment (Circle Medical
B.V., Wijchen, The Netherlands). This tip is designed to be used during tumor resection to avoid surgical trauma to the spinal cord surrounding an intramedullary tumor and the associated blood vessels.
12/28/2007
02:40 PM
Anatomy of the nuchal ligament and its surgical applications
Neurosurgery. 61(5) Operative Neurosurgery Supplement 2:301-304, November 2007
Although considered a basic maneuver for neurosurgical procedures, dissection of the musculature of the posterior cervical spine can be a source of complications during surgery. These complications include excessive blood loss, a loss of the plane of dissection, and injury to important structures such as the vertebral artery and nerve roots.
12/28/2007
02:38 PM
Stroke Awareness in Brazil - Alarming Results in a Community-Based Study
Stroke doi: 10.1161/STROKEAHA.107.493908
Stroke is the leading cause of death in Brazil. This community-based study assessed lay knowledge about stroke recognition and treatment and risk factors for cerebrovascular diseases and activation of emergency medical services in Brazil.
12/28/2007
02:37 PM
HSV encephalitis in a child with brain stem glioma - a rare complication of therapy - Case report and review of the neurosurgical literature
Child's Nervous System, Volume 23, Number 11, November 2007 , pp. 1347-1350(4)
A 13-year-old boy was diagnosed with an inoperable, biopsy-proven pontine grade II
astrocytoma. During radiotherapy, he developed status epilepticus controlled by thiopentone with intubation and ventilation.
12/28/2007
02:36 PM
Nonfunctioning endocrine tumor arising from intracranial ectopic pancreas associated with congenital brain malformation
Child's Nervous System, Volume 23, Number 11, November 2007 , pp. 1337-1340(4)
We report a case of a nonfunctioning pancreatic endocrine tumor arising from intracranial ectopic pancreatic tissue.
12/28/2007
02:25 PM
Epilepsy in pregnancy
British Journal of Midwifery, Vol. 15, Iss. 12, 06 Dec 2007, pp 740 - 745
Epilepsy affects 1 in 200 women of childbearing age and is a cause of maternal death. For the fetus and neonate, epilepsy is associated with a significant risk of major and minor congenital anomalies, related to the use of
anti-convulsant medication.
12/28/2007
02:24 PM
Do patients with psychogenic nonepileptic seizures produce trustworthy findings on neuropsychological tests
Epilepsia doi:10.1111/j.1528-1167.2007.01457.x
Drane et al. (2006) has recently raised the possibility that patients with psychogenic nonepileptic seizures
(PNES) may make poor effort in taking neuropsychological tests in comparison with patients with epilepsy (ES).
12/28/2007
02:23 PM
Absence status epilepsy - Delineation of a distinct idiopathic generalized epilepsy syndrome
Epilepsia doi:10.1111/j.1528-1167.2007.01467.x
Absence status epilepticus (AS) is a prolonged, generalized, and nonconvulsive seizure that may occur in various circumstances. We report a series of patients in whom recurrent, unprovoked, typical AS was the main clinical feature.
12/28/2007
02:22 PM
Clinical predictors in patients with refractory epilepsy exposed to levetiracetam - a single-center study
Acta Neurologica Scandinavica doi:10.1111/j.1600-0404.2007.00956.x
This aim of the study was to ascertain the importance of clinical parameters on the response to treatment in refractory epilepsy patients on levetiracetam (LEV).
12/28/2007
02:19 PM
WORLD HEALTH ORGANIZATION GRADES II AND III MENINGIOMAS ARE RARE IN THE CRANIAL BASE AND SPINE
Neurosurgery. 61(6):1194-1198, December 2007
This study was undertaken to assess a possible relationship between the tumor location and the incidence of World Health Organization (WHO) Grades II and III
meningiomas.
12/28/2007
02:18 PM
QUANTIFICATION OF HEMODYNAMIC CHANGES INDUCED BY VIRTUAL PLACEMENT OF MULTIPLE STENTS ACROSS A WIDE-NECKED BASILAR TRUNK ANEURYSM
Neurosurgery. 61(6):1305-1313, December 2007
The porous intravascular stents that are currently available may not cause complete aneurysm thrombosis and may therefore fail to provide durable protection against aneurysm rupture when used as a sole treatment modality. The goal of this study was to quantify the effects of porous stents on aneurysm hemodynamics using computational fluid dynamics.
12/28/2007
02:17 PM
PROGNOSTIC SIGNIFICANCE OF TRANSDURAL INVASION OF CRANIAL BASE MALIGNANCIES IN PATIENTS UNDERGOING CRANIOFACIAL RESECTION
Neurosurgery. 61(6):1178-1185, December 2007
Invasion of the brain and/or dura is a known negative prognostic factor for patients undergoing craniofacial resection for cranial base malignancy. However, an evaluation of factors that may affect prognosis in this patient subgroup has not been undertaken.
12/28/2007
02:16 PM
OUTCOME OF BRAIN ABSCESS BY CLOSTRIDIUM PERFRINGENS
Neurosurgery. 61(6):E1339, December 2007
Despite the aggressive infection of soft tissue caused by Clostridium perfringens (gas gangrene-necrotizing
fasciitis), a brain abscess with this bacteria treated by early surgical excision, debridement of necrotic tissue, and antibiotic coverage may be expected to have a good recovery.
12/28/2007
02:14 PM
MEASUREMENT OF HEAD IMPACTS IN COLLEGIATE FOOTBALL PLAYERS - RELATIONSHIP BETWEEN HEAD IMPACT BIOMECHANICS AND ACUTE CLINICAL OUTCOME AFTER CONCUSSION
Neurosurgery. 61(6):1244-1253, December 2007
To determine the relationship between recorded head accelerations and impact locations and acute clinical outcome of
symptomatology, neuropsychological, and postural stability tests after cerebral concussion in Division I collegiate football players.
12/28/2007
02:13 PM
MEASUREMENT OF HEAD IMPACTS IN COLLEGIATE FOOTBALL PLAYERS - CLINICAL MEASURES OF CONCUSSION AFTER HIGH- AND LOW-MAGNITUDE IMPACTS
Neurosurgery. 61(6):1236-1243, December 2007
It has been speculated that a theoretical injury threshold of 70 to 75 g may exist for concussions in football players. We aimed to investigate acute balance and neurocognitive performance after head impacts exceeding a theoretical injury threshold in the absence of both self-reported symptoms and a concussion diagnosis 24 hours before testing.
12/28/2007
02:12 PM
MEASUREMENT OF HEAD IMPACTS IN COLLEGIATE FOOTBALL PLAYERS - AN INVESTIGATION OF POSITIONAL AND EVENT-TYPE DIFFERENCES
Neurosurgery. 61(6):1229-1235, December 2007
There exists a need to better understand the biomechanical forces associated with head impacts in American football. The purpose of this study was to investigate whether or not differences in head accelerations existed between different player positions and different event types in collegiate football. We also sought to identify whether or not any associations existed between high-magnitude impacts and location of head impacts.
12/28/2007
02:11 PM
MALIGNANT PERIPHERAL NERVE SHEATH TUMOR OF THE OCCIPITAL REGION - CASE REPORT
Neurosurgery. 61(6):E1334-E1335, December 2007
A rare case of a malignant peripheral nerve sheath tumor of the occipital region is presented. The role of postoperative radiotherapy in such cases is reviewed.
12/28/2007
02:10 PM
MAGNETOENCEPHALOGRAPHIC STUDY OF POSTERIOR TIBIAL NERVE STIMULATION IN PATIENTS WITH INTRACRANIAL LESIONS AROUND THE CENTRAL SULCUS
Neurosurgery. 61(6):1209-1218, December 2007
To study interhemispheric differences of somatosensory evoked field (SEF) characteristics and the spatial distribution of equivalent current dipole sources in patients with unilateral hemispheric lesions around the central sulcus region.
12/28/2007
02:09 PM
INTRAVENTRICULAR DYSEMBRYOPLASTIC NEUROEPITHELIAL TUMOR - CASE REPORT
Neurosurgery. 61(6):E1332-E1333, December 2007
The most common localization of dysembryoplastic neuroepithelial tumors (DNTs) is the supratentorial cortex, often in the temporal lobe. However, intraventricular localization of a DNT is extremely rare.
12/28/2007
02:08 PM
GAMMA KNIFE RADIOSURGERY FOR TRIGEMINAL NEURALGIA - RESULTS AND POTENTIALLY PREDICTIVE PARAMETERS-PART I - IDIOPATHIC TRIGEMINAL NEURALGIA
Neurosurgery. 61(6):1254-1261, December 2007
Gamma knife radiosurgery (GKR) is an increasingly used, minimally invasive treatment option for patients with trigeminal neuralgia (TN) refractory to medical therapy. This retrospective study evaluates the long-term results and side effects of GKR in the treatment of TN focusing on potentially predictive factors.
12/28/2007
02:07 PM
EVALUATION OF PATIENTS WITH SPONTANEOUS SUBARACHNOID HEMORRHAGE AND NEGATIVE ANGIOGRAPHY
Neurosurgery. 61(6):1139-1151, December 2007
The evaluation of patients with subarachnoid hemorrhage (SAH) with negative initial catheter-based angiography is a diagnostic challenge. Better diagnostic strategies based on hemorrhage patterns are needed.
12/28/2007
02:06 PM
ETIOPATHOLOGICAL FACTORS RELATED TO HYDROCEPHALUS ASSOCIATED WITH VESTIBULAR SCHWANNOMA
Neurosurgery. 61(6):1186-1193, December 2007
We retrospectively analyzed various clinical factors to determine whether or not these factors are etiopathologically related to the development of hydrocephalus in patients with vestibular
schwannomas.
12/28/2007
02:05 PM
COMPLETION ANGIOGRAPHY FOR SURGICALLY TREATED CEREBRAL ANEURYSMS - AN ECONOMIC ANALYSIS
Neurosurgery. 61(6):1162-1169, December 2007
To compare cost-effectiveness of different strategies for completion angiography after cerebral aneurysm clipping.
12/28/2007
02:04 PM
CHARACTERISTICS OF NONTRAUMATIC SUBARACHNOID HEMORRHAGE IN THE UNITED STATES IN 2003
Neurosurgery. 61(6):1131-1138, December 2007
Substantial progress has been made in the diagnosis and treatment of subarachnoid hemorrhage
(SAH). However, studies of SAH in the United States do not include information more recent than 2001, precluding analysis of shifts in treatment methods. We examined the epidemiology and in-hospital outcomes of nontraumatic SAH in the United States.
12/28/2007
02:03 PM
CHALLENGES AND OPPORTUNITIES FOR RECRUITING A NEW GENERATION OF NEUROSURGEONS
Neurosurgery. 61(6):1314-1321, December 2007
SEVERAL FACTORS HAVE converged to raise concern among program directors about attracting and training the next generation of neurosurgeons.
12/28/2007
02:02 PM
CHAINED LIGHTNING - PART III-EMERGING TECHNOLOGY, NOVEL THERAPEUTIC STRATEGIES AND NEW ENERGY MODALITIES FOR RADIOSURGERY
Neurosurgery. 61(6):1111-1130, December 2007
RADIOSURGERY IS FUNDAMENTALLY the harnessing of energy and delivering it to a focal target for a therapeutic effect. The evolution of radiosurgical technology and practice has served toward refining methodologies for better conformal energy delivery.
12/28/2007
01:59 PM
BRAINSTEM CORTICOSPINAL TRACT DIFFUSION TENSOR IMAGING IN PATIENTS WITH PRIMARY POSTERIOR FOSSA NEOPLASMS STRATIFIED BY TUMOR TYPE - A STUDY OF ASSOCIATION WITH MOTOR WEAKNESS AND OUTCOME
Neurosurgery. 61(6):1199-1208, December 2007
Diffusion tensor imaging (DTI) allows in vivo delineation of brainstem white matter tracts. The purpose of this study was to determine whether or not abnormalities of DTI metrics and fiber tractography correlate with neurological deficits and clinical status in patients with primary posterior fossa tumors.
12/28/2007
01:58 PM
ADMISSION ANGIOGRAPHIC CEREBRAL CIRCULATION TIME MAY PREDICT SUBSEQUENT ANGIOGRAPHIC VASOSPASM AFTER ANEURYSMAL SUBARACHNOID HEMORRHAGE
Neurosurgery. 61(6):1152-1161, December 2007
Angiographic cerebral vasospasm occurs in approximately 70% of patients hospitalized after aneurysmal subarachnoid hemorrhage
(SAH) and is associated with poor outcome. In this study, we examined whether or not cerebral circulation time
(CCT) measured with digital subtraction angiography was associated with angiographic vasospasm.
12/28/2007
01:57 PM
A CASE OF CRANIAL FASCIITIS ORIGINATING WITHIN THE DIPLOIC SPACE OF AN ADULT - CASE REPORT
Neurosurgery. 61(6):E1338, December 2007
Cranial fasciitis rarely occurs as a circumscribed lesion in the diploic space without soft tissue involvement. It is even more rare in adults. We discuss the radiographic and pathological differential diagnosis for cranial fasciitis and review the literature regarding clinical presentation and prognosis.
12/27/2007
12:27 PM
What's New With the Frontal Lobes
Journal of the International Neuropsychological Society (2008), 14: 177-178
Miller and Cummings published their original text, The Human Frontal Lobes: Functions and Disorders, in 1999. At that time, their work was quite unique and provided a valuable reference for both health professionals and researchers in the emerging field of the frontal lobes.
12/27/2007
12:26 PM
Our Brain as Stone Age Computer
Journal of the International Neuropsychological Society (2008), 14: 174-176
Clinical neuropsychologists are most interested in the "what" of brain function. Neuropsychological assessment requires only a working knowledge of functional localization and the tests best suited to capture that specialization. The
"why" of cortical specialization is not necessary for good clinical work.
12/27/2007
12:25 PM
Neuropsychology and clinical neuroscience of persistent post-concussive syndrome
Journal of the International Neuropsychological Society (2008), 14: 1-22
On the mild end of the acquired brain injury spectrum, the terms concussion and mild traumatic brain injury
(mTBI) have been used interchangeably, where persistent post-concussive syndrome
(PPCS) has been a label given when symptoms persist for more than three months post-concussion.
12/27/2007
12:24 PM
Long-term compensatory treatment of organizational deficits in a patient with bilateral frontal lobe damage
Journal of the International Neuropsychological Society (2008), 14: 154-163
Evans et al. (1998) described compensatory strategy use in R.P., a patient with executive dysfunction following bilateral frontal lobe damage who had difficulty acting upon her intentions.
12/27/2007
12:23 PM
Inconsistency of performance on neglect subtype tests following acute right hemisphere stroke
Journal of the International Neuropsychological Society (2008), 14: 23-32
Hemispatial neglect has been conceptualized as having dissociable and potentially clinically relevant subtypes. However, the question of whether patient performance on neglect subtype measures is consistent over time remains largely unanswered.
12/27/2007
12:22 PM
Executive functioning in preschool children born very preterm - Relationship with early white matter pathology
Journal of the International Neuropsychological Society (2008), 14: 90-101
Despite evidence for executive dysfunction in school-aged preterm children, less is known about the early development of these difficulties or their underlying neuropathology. This study used prospective longitudinal data from a regional cohort of 88 very preterm and 98 full-term comparison children to examine the executive functioning
(EF) of preschool children born very preterm.
12/27/2007
12:20 PM
Detecting the significance of changes in performance on the Stroop Color-Word Test Rey's Verbal Learning Test, and the Letter Digit Substitution Test - The regression-based change approach
Journal of the International Neuropsychological Society (2008), 14: 71-80
Serial neuropsychological assessment is often conducted to monitor changes in the cognitive abilities of individuals over time. Because practice effects occur and the reliability of test scores is less than perfect, it is difficult to judge whether varying test results should be attributed to chance trends or to real changes in underlying cognitive abilities.
12/27/2007
12:20 PM
Depressive rumination reduces specificity of autobiographical memory recall in acquired brain injury
Journal of the International Neuropsychological Society (2008), 14: 63-70
Individuals with acquired brain injuries (ABI) often experience depression following injury, with estimated rates between 20 and 40% within the first year and up to 50% thereafter
(Fleminger et al., 2003).
12/27/2007
12:19 PM
All the Important Things You Wanted to Know About the Effects of Stroke - Location Location Location
Journal of the International Neuropsychological Society (2008), 14: 176-177
The Behavioral and Cognitive Neurology of Stroke is a very handy reference book for the bedside or brief office examination of the stroke patient. The initial chapter highlights the need for serial mental status exams during the critical initial post stroke period.
12/27/2007
12:16 PM
A demonstration of endogenous modulation of unilateral spatial neglect - The impact of apparent time-pressure on spatial bias
Journal of the International Neuropsychological Society (2008), 14: 33-41
Unilateral neglect, a lack of awareness for one side of space, is a common and debilitating consequence of stroke. Previous work has identified a relationship between enduring left neglect and diminished general alertness and shown that increasing alertness can temporarily reduce the severity of the spatial bias.
12/27/2007
12:12 PM
What is the role of motor simulation in action and object recognition - Evidence from apraxia
Cognitive Neuropsychology, Volume 24, Issue 8 December 2007 , pages 795 - 816
An important issue in contemporary cognitive neuroscience concerns the role of motor production processes in perceptual and conceptual analysis. To address this issue, we studied the performance of a large group of unilateral stroke patients across a range of tasks using the same set of common manipulable objects.
12/27/2007
11:17 AM
Modulation of Hippocampal Theta Oscillation by Histamine H3 Receptors
JPET 324:391-398, 2008
Preclinical findings demonstrate procognitive actions of histamine 3 (H3) receptor antagonists/inverse agonists. Since a prominent role of neuronal network oscillations of the hippocampus, such as theta band oscillation, has been recognized in numerous cognitive functions, in the present study, the potential involvement of H3 receptors in modulation of hippocampal theta activity has been investigated using various recording paradigms.
12/27/2007
11:16 AM
Gonadotropin-Inhibitory Hormone Neurons Interact Directly with Gonadotropin-Releasing Hormone-I and -II Neurons in European Starling Brain
Endocrinology Vol. 149, No. 1 268-278
Gonadotropin-inhibitory hormone (GnIH) is a hypothalamic dodecapeptide (SIKPSAYLPLRF-NH2) that directly inhibits gonadotropin synthesis and release from quail pituitary.
12/27/2007
11:13 AM
Usefulness of inflammatory and haemostatic markers to predict short-term risk for death in middle-aged ischaemic stroke patients
Acta Neurologica Scandinavica doi:10.1111/j.1600-0404.2007.00971.x
There is increasing evidence that inflammation and hypercoagulability play an important role in the pathophysiology of acute ischaemic stroke. We examined the in-hospital prognostic value on mortality of C-reactive protein (CRP), tumour necrosis factor-alpha
(TNF-alpha), fibrinogen and D-dimer in middle-aged ischaemic stroke patients.
12/27/2007
11:11 AM
Cerebral Hemorrhage in Infective Endocarditis Caused by Actinobacillus actinomycetemcomitans
American Journal of the Medical Sciences. 334(5):389-392, November 2007
Cerebral hemorrhage occurs rarely in endocarditis caused by Actinobacillus
actinomycetemcomitans.
12/27/2007
11:10 AM
Evaluation of the effect of intensity of care on mortality after traumatic brain injury
Critical Care Medicine. 36(1):282-290, January 2008
To evaluate the effect of age on intensity of care provided to traumatically brain-injured adults and to determine the influence of intensity of care on mortality at discharge and 12 months
postinjury, controlling for injury severity.
12/27/2007
11:07 AM
Prehospital neurologic deterioration in patients with intracerebral hemorrhage
Critical Care Medicine. 36(1):172-175, January 2008
Early neurologic deterioration has been studied in patients with intracerebral hemorrhage during hospitalization, but rates and factors associated with prehospital neurologic deterioration
(PND) are unknown.
12/27/2007
11:06 AM
Incidence and Prognosis of Transient Neurological Attacks
JAMA. 2007;298(24):2877-2885
Transient neurological attacks (TNAs) are attacks with temporary (<24 hours) neurological symptoms. These symptoms can be focal,
nonfocal, or a mixture of both. The prognostic significance of TNAs with focal symptoms (better known as transient ischemic attacks
[TIAs]) is well understood. Conversely, hardly anything is known about the prognostic significance of TNAs with nonfocal or mixed symptoms.
12/27/2007
11:04 AM
Transient Neurological Attacks
JAMA Vol. 298 No. 24, December 26, 2007
With symptoms lasting for up to 24 hours, transient neurological attacks are a warning sign that cerebrovascular disease (disease of the brain's blood vessels) may exist. Also known as a mini-stroke, a transient ischemic attack (TIA) is a focal (affecting one body part or system) type of transient neurological attack. Individuals who experience a TIA are at increased risk of having a stroke.
12/27/2007
11:03 AM
Clinical and psychopathological definition of the interictal dysphoric disorder of epilepsy
Epilepsia doi:10.1111/j.1528-1167.2007.01434.x
Different authors suggested the occurrence of a pleomorphic affective syndrome in patients with epilepsy named interictal dysphoric disorder
(IDD). We sought to investigate whether IDD occurs only in patients with epilepsy and to validate IDD features against DSM-IV criteria.
12/27/2007
11:01 AM
A newly detected tick-borne encephalitis TBE focus in south-east Sweden - A follow-up study of TBE virus TBEV seroprevalence
Scandinavian Journal of Infectious Diseases, Volume 40, Issue 1 2008 , pages 4 - 10
In 2002, two cases of tick-borne encephalitis (TBE) were diagnosed in inhabitants of a tick endemic area on in south-east Sweden. During the previous 25 y, only 2 other cases of TBE had been diagnosed in that region of Sweden.
12/27/2007
10:58 AM
Alterations of the sense of self and personality in Parkinson's disease
International Journal of Geriatric Psychiatry Volume 23, Issue 1 , Pages 79 - 84
We hypothesized that alterations of subcomponents (harm-avoidance) of personality and the sense of Self in patients with PD would be associated with executive cognitive dysfunction.
12/27/2007
10:56 AM
GABA Alpha receptor-mediated activation of L-type calcium channels induces neuronal excitation in surgically resected human hypothalamic hamartomas
Epilepsia doi:10.1111/j.1528-1167.2007.01455.x
The human hypothalamic hamartoma (HH) is a rare, intrinsically epileptogenic lesion associated with gelastic seizures, but the underlying mechanisms remain unclear. Here, we examined the role of GABA A receptors in surgically resected HH tissue.
12/27/2007
10:50 AM
Subcortical Lacunes Are Associated With Executive Dysfunction in Cognitively Normal Elderly
Stroke doi: 10.1161/STROKEAHA.107.491795
The relationship between subcortical ischemic vascular disease (SIVD) and cognition in normal elderly is unclear, in part because of methodological inconsistencies across studies.
12/27/2007
10:49 AM
Functional MRI Evaluation of Tumor Response in Patients with Neuroendocrine Hepatic Metastasis Treated with Transcatheter Arterial Chemoembolization
AJR 2008; 190:67-73
The purpose of this study was to evaluate contrast-enhanced and diffusion-weighted MRI changes in neuroendocrine tumors treated with transcatheter arterial chemoembolization
(TACE).
12/27/2007
10:45 AM
Local Dystrophin Restoration with Antisense Oligonucleotide PRO051
New England Journal of Medicine Volume 357:2677-2686 December 27, 2007 Number 26
Duchenne's muscular dystrophy is associated with severe, progressive muscle weakness and typically leads to death between the ages of 20 and 35 years.
12/27/2007
10:43 AM
Aborted and refractory status epilepticus in children - A comparative analysis
Epilepsia doi:10.1111/j.1528-1167.2007.01465.x
The aims of this retrospective study were: (1) to compare the demographics, clinical characteristics, etiology, and EEG findings of status epilepticus aborted with medication (ASE) and refractory status epilepticus
(RSE), (2) to describe the treatment response of status epilepticus (SE), and (3) to determine predictors of long-term outcome in children with SE.
12/27/2007
10:41 AM
Association of Characteristics of Blood Pressure Profiles and Stroke Outcomes in the ECASS-II Trial
Stroke doi: 10.1161/STROKEAHA.107.492330
Certain characteristics of early blood pressure (BP) profiles were reported to be independent predictors of long-term outcome in the first European Cooperative Acute Stroke Study
(ECASS-I) trial. The aim of the study was to find out the association of BP profiles with functional outcome, mortality, and hemorrhagic complications in the
ECASS-II database.
12/27/2007
10:26 AM
Treatment of Hyperglycemia In Ischemic Stroke THIS - A Randomized Pilot Trial
Stroke doi: 10.1161/STROKEAHA.107.493544
Hyperglycemia may worsen brain injury during acute cerebral infarction. We tested the feasibility and tolerability of aggressive hyperglycemia correction with intravenous insulin compared with usual care during acute cerebral infarction.
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