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Although essential tremor (ET) is one of the most common neurologic disorders, there have been few postmortem studies. We recently reported postmortem changes (torpedoes and Bergmann
gliosis) in the cerebellar cortex in a few ET cases.
National advisories recommend statin therapy as an element of secondary prevention for patients with ischemic stroke or transient ischemic attack of atherosclerotic origin. Statins are of proven benefit in persons at high risk of vascular disease.
The benefit of intravenous recombinant tissue plasminogen activator (rtPA) in acute stroke is linked to clot lysis and artery
recanalization. Argatroban is a direct thrombin inhibitor that safely augments the benefit of rtPA in animal stroke models. There are no human data on this combination.
A retrospective study of 28 patients identified with subdural empyema (SE) at the Department of Neurosurgery between the years 1995 and 2005 was carried out. SE occurred in all patients following bacterial meningitis.
Brain Research Reviews Volume 52, Issue 1 , 30 August 2006, Pages 107-118
This review discusses the effects of prenatal alcohol exposure on the developing brain and the potential use of derived peptides from activity-dependent neurotrophic factor
(ADNF) and activity-dependent neuroprotective protein (ADNP) in neuroprotection against the insults of alcohol. Alcohol is known to impede the growth of the central nervous system and to induce neurodegeneration through cellular apoptosis.
Brain Research Reviews Volume 52, Issue 1 , 30 August 2006, Pages 119-130
Many studies have been conducted to test the potentially beneficial effects of physical activity on cognition. The results of meta-analytic reviews of this literature suggest that there is a positive association between participation in physical activity and cognitive performance.
Decades of research have provided substantial evidence of memory impairments in patients with temporal lobe epilepsy
(TLE), including deficits in the encoding, storage, and retrieval of new information. These findings are not surprising, given the associated underlying
neuroanatomy, including the hippocampus and surrounding medial temporal lobe structures.
Epilepsy occurs at a higher incidence and is more prevalent in people with an intellectual disability than in the general population. Nonetheless, we have insufficient knowledge of the extra needs of people with epilepsy and intellectual disability, of their families, and of the living environment.
Echinodorus berteroi is an aquatic plant found in Central America and the Caribbean to which antiepileptic action has been attributed by folk medicine. The aim of the present study was to investigate the potential behavioral and antiepileptic effect of decoctions (1, 5, and 30%,
intraperitoneally) of the dried roots.
Archives of Physical Medicine and Rehabilitation Volume 87, Issue 7 , July 2006, Pages 967-973
Lord SE, Rochester L, Weatherall M, McPherson KM, McNaughton HK. The effect of environment and task on gait parameters after stroke: a randomized comparison of measurement conditions.
Archives of Physical Medicine and Rehabilitation Volume 87, Issue 7 , July 2006, Pages 962-966
Rabadi MH, Rabadi FM. Comparison of the Action Research Arm Test and the
Fugl-Meyer Assessment as measures of upper-extremity motor weakness after stroke.
International Journal of Rehabilitation Research. 29(3):243-246, September 2006
This study aimed to evaluate the impact of physical therapy on the quality of life of patients presenting with a motor deficit caused by ischemic stroke at the median cerebral artery.
To determine the prevalence of stroke and its distribution by age, sex and clinical type, and to use the outcomes for prevention, care and rehabilitation.
Although it is estimated that > 1 billion passengers travel by air worldwide each year, the incidence of in-flight emergencies is low. However, due to nonstandardized reporting requirements for in-flight medical emergencies, the true incidence of pulmonary barotrauma in airplane passengers is unknown. We describe the case of a passenger with an asymptomatic intrapulmonary cyst in whom a severe case of cerebral gas embolism developed during an aircraft flight. The decrease in ambient pressure during the aircraft climb resulted in expansion of the cyst volume based on Boyle’s law (pressure x volume = constant). Due to the cyst expansion, we believe tears in the wall led to the leakage of air into the surrounding vessels followed by brain gas emboli. Adult patients with intrapulmonary cysts should be strongly considered for cyst resection or should at least be advised to abstain from activities leading to considerable changes in ambient pressure.
A 13-year-old girl presented with consciousness disturbance, right hemiparesis, and impairment of hearing, swallowing, and ocular movements. A magnetic resonance image demonstrated marked hydrocephalus due to a large cystic tumor (40 × 40 × 30 mm) in the midbrain. Emergency ventricular drainage and stereotactic cyst puncture dramatically improved her condition. Since her family did not agree to surgery on the brain stem, radiotherapy was performed after ventriculoperitoneal shunting. Conventional radiotherapy of 50.4 Gy was temporarily effective, and the growth of the tumor was stabilized until approximately 8 months later when regrowth was noticed.
Journal of Neurosurgical Anesthesiology. 18(3):179-184, July 2006
The aim of this study was to compare the effects of 3 different sedative-analgesic regimens in patients with intracranial mass lesions undergoing stereotactic brain biopsy.
Journal of Neurosurgical Anesthesiology. 18(3):200-204, July 2006
Progressive intracerebral contusions are a major problem in the management of patients with severe traumatic brain injury that is also linked to worse outcome. Microdialysis studies have revealed that lactate levels are very high inside contusions, corresponding to significant acidosis.
Journal of Neurosurgical Anesthesiology. 18(3):170-178, July 2006
Cerebral ischemia is recognized as one of the most important mechanisms responsible for secondary brain damage following severe traumatic brain injury
(TBI), contributing to an increased mortality and a worse neurologic outcome.
British Journal of Haematology, Volume 134, Number 3, August 2006, pp. 333-339(7)
Elevated velocity in the internal carotid artery (ICA) or middle cerebral artery (MCA), detected by transcranial Doppler
(TCD) ultrasonography, predicts an increased risk of stroke in children with sickle cell disease (SCD).
To study the effectiveness of including acute hemorrhagic stroke in acute stroke program with an emphasis on use of activated factor VII
(novoseven). 2) To study the effect of NOVOSEVEN administration in acute hemorrhagic stroke presenting in the first 4 hours of onset.
PEDIATRICS Vol. 118 No. 2 August 2006, pp. 626-633
Mixed-density convexity subdural hematoma and interhemispheric subdural hematoma suggest nonaccidental head injury. The purpose of this retrospective observational study is to investigate subdural hematoma on noncontrast computed tomography in infants with nonaccidental head injury and to compare these findings in infants with accidental head trauma for whom the date of injury was known.
The Clinical Neuropsychologist Volume 20, Number 3 / September 2006 453 - 468
To address concerns about self-awareness deficits and the validity of self-ratings by patients with head injury (HI), the current study examines mean differences and correlations between self-ratings from 52 patients with HI and ratings of the patient by informants using the revised NEO Personality Inventory (NEO-PI-R).
The Clinical Neuropsychologist Volume 20, Number 3 / September 2006 491 - 512
The present study used a known-groups design to determine the classification accuracy of 10 MMPI-2 validity scales and indicators in the detection of cognitive malingering in traumatic brain injury. Participants were 259 traumatic brain injury and 133 general clinical patients seen for neuropsychological evaluation.
Journal of Neurosurgical Anesthesiology. 18(3):185-188, July 2006
Cerebral pathology may alter the cerebrovascular reactivity to carbon dioxide (CO2). In the present study, in patients with brain tumors, we examined the cerebral vascular reactivity to CO2 in the cerebral hemispheres with and without tumors under intravenous and inhalational anesthesia.
In this nonblinded study, the combination of aspirin plus dipyridamole was more effective than aspirin alone in preventing death from all vascular causes, nonfatal stroke, nonfatal myocardial infarction, or major bleeding complications.
This study investigates the clinical features of epilepsy in 20 patients with brain malformation. Epileptic seizures were recognized in 15 patients, 12 of whom had their first seizure by 1 year of age. Partial seizure was the initial seizure type in 10 patients.
Despite major improvement in surgical techniques and intensive care management, stroke remains one of the most devastating complications of coronary artery bypass grafting
(CABG). We aimed to determine factors predicting the occurrence of stroke during
CABG. A special interest was focused on preoperative therapies.
The Journal of Neuroscience, August 2, 2006, 26(31):8069-8073
We identified areas of the brain that are critical for naming pictures of objects, using a new methodology for testing which components of a network of brain regions are essential for that task.
Cardiovascular disease is the leading cause of death in long-term stroke survivors, and whole-body glucose metabolism is strongly linked to cardiovascular disease risk. This study provides important preliminary information on the prevalence of abnormal glucose metabolism in chronic stroke patients (mean 3 years after stroke) and reports on the utility of screening for abnormalities using fasting plasma glucose
(FPG) in this population.
The relationship between body mass index (BMI) and stroke mortality remains unclear. The aim of the present study was to elucidate the relationship between BMI and stroke death in a representative cohort of Japanese men and women.
Thirty two patients between 6 months and 14 years of age with tubercular meningitis were evaluated for brain stem auditory evoked response (BAER) and Visual evoked responses
(VER), within 7 days of admission. Absolute latencies and interpeak latencies were compared with values obtained from normal children. BAER abnormality was found in 56.25% and VER in 28% children, respectively. BAER abnormality correlated with Glasgow Coma Scale at admission and discharge, stage of meningitis, raised intracranial pressure, seizure activity, and poor outcome. VER abnormality correlated with abnormal fundus findings only.
Although studies have examined the incidence of stroke in heart failure
(HF), their findings are inconsistent and difficult to interpret because of heterogeneity in study design and population. Although HF remains a highly fatal disease, the excess mortality imparted from stroke is unknown.
Platelet aggregation plays an important role in the pathogenesis of thromboembolic cerebrovascular disease. Platelet aggregation ratio (PAR) and its derivates have been used successfully to identify the effectiveness of antiplatelet agents and their optimum dosage in patients suffering from stroke.
Journal of Neurology, Neurosurgery, and Psychiatry 2006;77:850-855
To identify abnormal white matter projections in patients with nmTBI with cognitive impairments using diffusion tensor magnetic resonance imaging (DTI).
In Iran, a Middle-East country, no disability scale has been translated and validated for use in stroke clinical trials. This study was designed to translate the Barthel Index and make its Persian translated form valid and reliable.
Journal of Neurology, Neurosurgery, and Psychiatry 2006;77:877-879
In July 1988, 20 tonnes of aluminium sulphate was discharged by the South West Water Authority into the drinking water supplied to a large region of North Cornwall. Up to 20 000 people were exposed to concentrations of aluminium which were 500–3000 times the acceptable limit under European Union legislation (0.200 mg/l). Although this incident is currently the topic of a government inquiry, nothing is known about its longer-term repercussions on human health. The first neuropathological examination of a person who was exposed and died of an unspecified neurological condition was carried out.
European Heart Journal Volume 27, Number 16 Pp. 1954-1964
Underuse of warfarin for stroke prophylaxis in atrial fibrillation (AF) is extensive and represents a major problem in clinical practice. To identify factors associated with warfarin treatment in eligible AF patients.
Journal of Neurology, Neurosurgery, and Psychiatry 2006;77:826-829
The benefit of intravenous tissue plasminogen activator (tPA) given within 3 h of acute ischaemic stroke to patients over 80 years of age is uncertain.
The Acute Candesartan Cilexetil Therapy in Stroke Survivors (ACCESS) study indicated that early treatment with an angiotensin type 1 receptor blocker in acute stroke patients who had relatively high blood pressure improved cardiovascular morbidity and mortality in the chronic stage.
Myocardial infarction is the leading cause of death today. With the fast progress in pharmacotherapy and revascularization technology, outcomes following a myocardial infarction have become very favorable.
The authors studied four hemiparetic patients with large unilateral periventricular brain lesions acquired during the early third trimester of pregnancy. fMRI and magnetoencephalography demonstrated that the primary somatosensory representation of their paretic hands was nevertheless located in the contralateral rolandic cortex.
Horizontal gaze palsy with progressive scoliosis (HGPPS) is caused by mutations in the ROBO3 gene, critical for the crossing of long ascending medial lemniscal and descending corticospinal tracts in the medulla. Diffusion tensor imaging in a patient with HGGPS revealed the absence of major pontine crossing fiber tracts and no decussation of the superior cerebellar peduncles. Mutations in the ROBO3 gene lead to a widespread lack of crossing fibers throughout the brainstem.
The authors measured the association of early ischemic change on CT scan, measured using the Alberta Stroke Programme Early CT score (ASPECTS), and functional outcome in 825 patients with anterior circulation stroke treated with IV thrombolysis within 3 hours of onset.
The authors examined the relationship in women between age at first birth, parity, and subarachnoid hemorrhage mortality. They followed each woman from the time of her first birth and linked vital status with a mortality database. The risk was increased by 8% for each additional year of mother's age at first birth. The relative risk was 0.63 for women who had borne two children and 0.62 for women with three or more births.
Differentiating idiopathic late-onset cerebellar ataxia (ILOCA) from ataxia due to the cerebellar subtype of multiple-system atrophy
(MSA-C) can be difficult in the early stages of the disease
To assess whether educational attainment, a correlate of cognitive reserve, predicts the amount of cognitive decline associated with a new brain infarct.
To describe the frequency, risk factors, and outcome of intracerebral hemorrhage
(ICH) in pregnancy and the postpartum period using a large database of US inpatient hospitalizations.
Journal of Vascular Surgery Volume 43, Issue 6 , June 2006, Pages 1175-1182
To determine the perioperative mortality, myocardial infarction rate, and long-term survival of patients with critical limb ischemia
(CLI) compared with those with intermittent claudication (IC) within a cohort selected for significant coronary artery disease, a secondary analysis was conducted of a prospective, randomized, multicenter trial of Coronary Artery Revascularization Prophylaxis (CARP) before peripheral vascular surgery.
Journal of Clinical Oncology, Vol 24, No 22 (August 1), 2006: pp. 3644-3650
TM-601 binds to malignant brain tumor cells with high affinity and does not seem to bind to normal brain tissue. Preclinical studies suggest that iodine-131 (131I) –TM-601 may be an effective targeted therapy for the treatment of
glioma. We evaluated the safety, biodistribution, and dosimetry of
intracavitary-administered 131I-TM-601 in patients with recurrent
glioma.
Journal of the American Geriatrics Society, Volume 54, Number 7, July 2006, pp. 1082-1088(7)
To determine fracture risk in U.S. stroke patients and identify patient characteristics that predict highest fracture risk in two complementary cohorts.
Archives of Clinical Neuropsychology
Volume 21, Issue 4 , May 2006, Pages 249-254
The letter memory test (LMT) is a computerized forced-choice test of malingering detection including two face valid difficulty manipulations: increase in target stimulus length and increase of response foils. Prior research suggests the LMT shows promise as a malingering detection measure. In the present study, the utility of the LMT in the identification of malingering was further explored, using a counterbalanced design in a simulated malingering sample.
Archives of Clinical Neuropsychology
Volume 21, Issue 4 , May 2006, Pages 321-325
Cortical lesion patients were tested on the Cognitive Assessment System (CAS) in the post-acute phase (median = 1 month) to determine the degree of sensitivity and specificity of the CAS subtests to neuropsychological impairment.
Archives of Clinical Neuropsychology Volume 21, Issue 4 , May 2006, Pages 339-347
This study examined postconcussion-like symptoms in a group of university students and explored their relationships to neuropsychological function performance. A sample of 124 students was recruited. All of the participants received the Rivermead Post-Concussion Symptoms Questionnaire
(RPQ) and completed a comprehensive set of neuropsychological tests. They reported a relatively high base rate of
postconcussion-like symptoms.
Archives of Clinical Neuropsychology Volume 21, Issue 4 , May 2006, Pages 311-320
Executive functioning has been repeatedly linked to the integrity of instrumental activities of daily living
(IADL). The present study examined the association of multiple executive functioning elements (i.e., working memory, generation, inhibition, planning, and sequencing) to IADLs among an older adult cohort at risk for future cognitive and functional decline.
The effects of war-zone deployment on neuropsychological health remain poorly understood. Neuropsychological performance deficits serve as sensitive measures of neural dysfunction and are often associated with psychosocial and occupational problems. Previous studies have not conducted objective neuropsychological assessments both before and after a major war-zone deployment.
Archives of Clinical Neuropsychology Volume 21, Issue 4 , May 2006, Pages 255-273
Although there is a large body of research on mild traumatic brain injury
(MTBI), the portion that pertains to acute patients (those less than 1 month
postinjury) is relatively small and yields inconsistent findings. The potential contribution of non-neurological factors, such as pain and emotional distress, to the clinical picture in this population is also lacking.
Archives of Clinical Neuropsychology Volume 21, Issue 4 , May 2006, Pages 287-291
Research has shown that subjects at risk for cerebral dysfunction endorse more complex partial seizure symptoms than low risk controls. It has been suggested that seizure activity be regarded as occurring on a continuum of neurobehavioral dysfunction, rather than as a discrete syndrome. The present study assessed seizure symptom endorsement in individuals reporting a positive history of head injury.
Archives of Clinical Neuropsychology Volume 21, Issue 4 , May 2006, Pages 349-358
Ideomotor apraxia (IMA) of lower limbs has rarely been investigated systematically. This is the aim of the current study. Thirty-five patients with a unilateral stroke in the left hemisphere were tested within 30 days from onset with an upper limb IMA test and with a newly devised test assessing leg
IMA. Seventeen patients presented with arm apraxia, six of them also showed severe leg
apraxia. Results suggest that IMA of lower limbs emerges in association with severe arm IMA in patients with large lesions, and is a sign of general severity of the patient's conditions.
Archives of Clinical Neuropsychology
Volume 21, Issue 4 , May 2006, Pages 293-296
Research has shown that individuals who have sustained mild head injury demonstrate a slowed speed of processing that is exacerbated by fatigue/stress. We administered the Paced Auditory Serial Addition Test
(PASAT) at the beginning and at the end of a 4-h experimental protocol to determine whether fatigue or a stressor would result in poorer scores for individuals who had previously sustained mild head injury.
PEDIATRICS Vol. 118 No. 2 August 2006, pp. e371-e378
Primary generalized tonic-clonic seizures are relatively more common among children than among adults. Primary generalized
tonic-clonic seizures are associated with increased risk of injury and death. Therefore, effective control of primary generalized
tonic-clonic seizures is necessary to reduce epilepsy-related morbidity and mortality. Lamotrigine has demonstrated efficacy from published randomized clinical trials for childhood partial seizures, absence seizures, and for the generalized seizures associated with
Lennox-Gastaut syndrome.
Recurrent stroke is the greatest risk faced by survivors of stroke or transient ischemic attack (TIA), according to guidelines released by the American Heart Association/ American Stroke Association
(AHA/ASA).
Neuropathology, Volume 26, Number 4, August 2006, pp. 283-292(10)
Various types of poststroke hyperactivity exist in humans, but studies of each mechanism using animal models are scarce. We aimed to analyze the heterogeneity of postischemic hyperlocomotion and to identify the ischemic lesions responsible for postischemic hyperlocomotion in rodent models of focal ischemia.
Neuropathology, Volume 26, Number 4, August 2006, pp. 298-306(9)
We morphologically examined human brains several years after a territorial ischemic stroke to assess the development of progressing white matter damage and its
pathomechanisms. Our investigations focused on the role of TGF-ß, one of the factors whose expression increases after tissue damage, and its receptor endoglin in the propagation of postischemic injury.
Neuropathology, Volume 26, Number 4, August 2006, pp. 323-328(6)
An autopsy case of chronic thrombotic occlusion of the superior sagittal sinus
(SSS) with an unusually protracted clinical course is reported. The patient was an 84-year-old man without any predisposing conditions for thrombosis. The clinical features were atypical and were characterized by recurrent cerebral subcortical hemorrhages. The autopsy revealed a large, organized thrombus in the SSS and extensive hemorrhagic infarction of the bilateral parasagittal region of the cerebral hemispheres.
Current Opinion in Psychiatry. 19(5):497-501, September 2006
In our modern, performance managed National Health Service, quality has become a key target. Quality assurance has become a statutory duty and the National Health Service is inundated with policy documents and performance measures in most areas of mainstream healthcare. Performance against such measures will be monitored by powerful independent regulatory bodies. It is therefore timely to look at what specific quality measures there are for services for people with intellectual disability.
Magnetic Resonance Imaging
Volume 24, Issue 6 , July 2006, Pages 699-706
A magnetic resonance proton spectroscopic imaging (SI) technique was developed to measure regional brain temperatures in human subjects. The technique was validated in a homogeneous phantom and in four healthy volunteers.
Journal of Pain and Symptom Management Volume 32, Issue 2 , August 2006, Pages 148-154
This study explored the use of complementary and alternative medicine (CAM) approaches and their relationship with demographic and disease characteristics and quality of life
(QOL) in the primary brain tumor (PBT) population. One hundred one PBT patients were enrolled in this study. The results showed that 34% of patients reported using CAM. Forty-one percent reported using more than one type of CAM. The average cost of each CAM used per month was $69, with 20% of patients spending more than $100 per month.
The British Journal of Psychiatry (2006) 189: 182-183
Voltage-gated potassium channel antibody encephalopathy, a rare cause of limbic encephalopathy, typically presents with memory impairment and seizures. Psychiatric symptoms have not been emphasised in the literature. Here we describe a 58-year-old man who presented with panic attacks and psychogenic non-epileptic seizures and, later on, developed delusions and hallucinations and then confusion. He was found to have antibodies to voltage-gated potassium channels. Treatment with immuno-modulatory therapy resulted in almost complete recovery.
Recent studies have reported a significant inflammatory reaction in the brain and the systemic circulation after traumatic brain injury
(TBI). Although there is growing knowledge and understanding of the mechanisms and mediators involved in the proinflammatory reaction, little is known about the anti-inflammatory mediators in the brain. As tumor necrosis factor [alpha]
(TNF-[alpha]) plays a detrimental role in the initiation and promotion of the proinflammatory reactions after
TBI, the endogenous scavenger system, represented by the soluble TNF receptors
(sTNFRs) p55 and p75, seems to have an important anti-inflammatory capacity by binding to circulating
TNF-[alpha].
This article represents the recommendations for the management of spontaneous intracerebral haemorrhage of the European Stroke Initiative
(EUSI). These recommendations are endorsed by the 3 European societies which are represented in the
EUSI: the European Stroke Council, the European Neurological Society and the European Federation of Neurological Societies.
Journal of Cognitive Neuroscience. 2006;18:1253-1265
Medial temporal lobe structures such as the hippocampus have been shown to play a critical role in mnemonic processes, with additional recruitment of the amygdala when memories contain emotional content. Thus far, studies that have examined the relationship between amygdala activity and memory have typically relied on emotional content of the kind that is rarely encountered in day-to-day interactions. The present event-related functional magnetic resonance imaging study investigates whether amygdala activity supports emotional memory during the more subtle social interactions that punctuate everyday life.
Journal of Cognitive Neuroscience. 2006;18:1266-1276
Cognitive strategies used in volitional emotion regulation include self-distraction and reappraisal (reinterpretation). There is debate as to what the psychological and neurobiological mechanisms underlying these strategies are. For example, it is unclear whether self-distraction and reappraisal, although distinct at a phenomenological level, are also mediated by distinct neural processes. This is partly because imaging studies on reappraisal and self-distraction have been performed in different emotional contexts and are difficult to compare.
Journal of Cognitive Neuroscience. 2006;18:1380-1393
The purpose of the present study was to investigate the effect of harmonic expectancy violations on emotions. Subjective response measures for tension and emotionality, as well as electrodermal activity
(EDA) and heart rate (HR), were recorded from 24 subjects (12 musicians and 12
nonmusicians) to observe the effect of expectancy violations on subjective and physiological measures of emotions. In addition, an electroencephalogram was recorded to observe the neural correlates for detecting these violations.
Journal of Emergency Medicine Volume 31, Issue 2 , August 2006, Pages 165-167
Internuclear ophthalmoplegia is a syndrome that develops due to a lesion of the medial longitudinal fasciculus. This lesion is mostly caused by multiple sclerosis (usually bilaterally), and only rarely by head injury. A case is presented of unilateral internuclear ophthalmoplegia as an isolated sequel of minor head trauma, which eventually resolved.
Cephalalgia, Volume 26, Number 8, August 2006, pp. 934-939(6)
The aim of this study was to investigate the prevalence of patent foramen ovale
(PFO) in a consecutive unselected cohort of migraine patients (with and without aura) and compare it with a group of ischaemic young and elderly stroke patients. One hundred and forty-one migraine patients were compared with 330 stroke patients (130 young patients; 200 elderly patients) selected from our hospital stroke data bank.
Poststroke hyperglycemia (PSH) is common and has adverse effects on outcome. In this observational study, we aimed to describe the frequency and temporal profile of PSH using a continuous glucose monitoring system
(CGMS) in patients with and without diabetes.
Pediatric Infectious Disease Journal. 25(8):754-756, August 2006
Purulent fluid collections, including brain abscess and subdural empyema, are exceedingly rare in association with meningococcal meningitis. We present a 5-month-old infant with meningococcal meningitis and sepsis complicated by an intracerebral abscess.
Current Opinion in Psychiatry. 19(5):502-507, September 2006
This paper summarizes trends in the research literature about stress and burnout in the lives of people who are the professional carers of people with intellectual disability. The principal time period considered was from 2004 to 2006.
Current Opinion in Psychiatry. 19(5):492-496, September 2006
On the basis of the relevance of adequate epilepsy treatment (antiepileptic drugs, surgery and vagus nerve stimulation) for people with intellectual disabilities, all articles, published from the beginning of 2005 to March 2006 and searched by MEDLINE, on this topic were reviewed.
Journal of Paediatrics and Child Health, Volume 42, Number 7, July/August 2006, pp. 477-479(3)
Most vascular diseases have a tendency to affect both heart and the brain. Intracranial aneurysms are more often found in patients with aorta coarctation than in general population, and aneurysm rupture occurs much earlier in these patients. Here, we report a case of aorta coarctation which was diagnosed with its cerebrovascular complications. Before presenting with cerebrovascular complications, the disease can easily be diagnosed with physical examination and non-invasive radiological investigations like echocardiography or cardiac magnetic resonance imaging.
Journal of Clinical Oncology, Vol 24, No 22 (August 1), 2006: pp. 3636-3643
The intent of this study was to determine whether baseline measures of functional capacity and performance could be used to predict survival in adults following the diagnosis of brain tumors.
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