www.ventilatorcare.com Northeast Center for Special Care Respiratory Pulmonary Journal Watch

Movement Disorders and TBI Podcast

Tue, 2 Jun 2009 10:55:55 -0400

Host: Gerry Brooks, MA, CCC, CBIST

Time: 2857

In this program we discuss the different kinds of movement disorders common after an brain injury including risk, severity, and how movement disorders may very with the type of brain injury someone has.

Evaluation of movement disorders as well as treatment options are considered in this informative Podcast.

MDCT evaluation of pulmonary embolism in children and young adults following a lateral tunnel Fontan procedure: optimizing contrast-enhancement techniques

Tue, 2 Jun 2009 10:55:55 -0400

Pediatric Radiology 0301-0449 (Print) 10.1007/s00247-009-1304-8

Pulmonary embolism (PE) is a life-threatening thromboembolic complication in patients who have undergone a Fontan procedure for augmenting pulmonary blood flow in the setting of single-ventricle physiology.

Acute exacerbation of idiopathic pulmonary fibrosis as the initial presentation of the disease

Tue, 2 Jun 2009 10:55:10 -0400

EUROPEAN RESPIRATORY REVIEW, 2009;18: 129-132

The clinical course of patients with idiopathic pulmonary fibrosis (IPF) is generally marked by a decline in pulmonary function over time, although recently there is increasing recognition that fatal deterioration from acute exacerbation can occur at any stage.

Vastus lateralis NA+-K+-ATpase activity, protein, and isoform distribution in chronic obstructive pulmonary disease

Tue, 2 Jun 2009 10:54:17 -0400

Muscle & Nerve Published Online: 26 May 2009

In this study we investigate the hypothesis that protein abundance, isoform distribution, and maximal catalytic activity of sodium-potassium-adenosine triphosphatase (Na+-K+-ATPase) would be altered in muscle of patients with moderate to severe chronic obstructive pulmonary disease (COPD).

SAVE THE DATE: 2009 Mid-Hudson Brain Injury Rehabilitation Conference

Tue, 2 Jun 2009 10:53:19 -0400

Northeast Center for Special Care presents the 5th Annual Mid-Hudson Brain Injury Rehabilitation Conference on Thursday October 8, 2009 at Bard College, Annandale-on-Hudson, NY.

The theme for this years conference is: Beyond Recovery: Life After TBI.

The emphasis in rehabilitation is typically on overcoming the challenges associated with disability. However, some of the most serious challenges confronting the individual--especially in the later stages of recovery--may have less to do with disability than with the human condition itself.

The annual Mid-Hudson Brain Injury Rehabilitation Conference is aimed at professionals and clinicians who support Traumatic Brain Injury survivors and has featured world renowned experts in the field of neurorehabilitation.

Join the mailing list and receive the conference agenda and registration information when it is published.

Suppression of pulmonary vasculature in lung perfusion MRI using correlation analysis

Tue, 2 Jun 2009 10:53:19 -0400

European Radiology 0938-7994 (Print) 10.1007/s00330-009-1464-9

The purpose of the study was to evaluate the feasibility of suppressing the pulmonary vasculature in lung perfusion MRI using cross-correlation analysis (CCA).

Soluble Vascular Endothelial Growth Factor Receptor 1 in Tracheal Aspirate Fluid of Preterm Neonates at Birth May Be Predictive of Bronchopulmonary Dysplasia/Chronic Lung Disease

Tue, 2 Jun 2009 10:52:40 -0400

PEDIATRICS Vol. 123 No. 6 June 2009

We tested the hypothesis that soluble vascular endothelial growth factor receptors are involved in the development of bronchopulmonary dysplasia/chronic lung disease.

Tracheobronchial Pulmonary Disease Associated With Pyoderma Gangrenosum

Tue, 2 Jun 2009 10:51:42 -0400

Mayo Clinic Proceedings June 2009 vol. 84 no. 6 555-557

We report a tracheobronchial pulmonary manifestation caused by pyoderma gangrenosum, a neutrophilic dermatosis of unknown etiology.

Progressive stridor: could it be a congenital cystic lung disease?

Tue, 2 Jun 2009 10:50:53 -0400

Acta Pediatrica Published Online: 28 May 2009

Bronchogenic cyst of the mediastinum, a cause of stridor early in life, is the result of abnormal budding of the ventral segment of the primitive foregut. Bronchogenic cysts are often asymptomatic in older children and adults.

Predicting Mortality in Patients with Ventilator-Associated Pneumonia: The APACHE II Score versus the New IBMP-10 Score

Tue, 2 Jun 2009 10:49:52 -0400

Clinical Infectious Diseases 2009;49:000-000

Ventilator-associated pneumonia (VAP) is the leading cause of mortality associated with nosocomial infection.

Electrical impedance tomography compared to positron emission tomography for the measurement of regional lung ventilation: an experimental study

Tue, 2 Jun 2009 10:48:54 -0400

Critical Care 2009, 13:R82doi:10.1186/cc7900

Electrical impedance tomography (EIT), which can assess regional lung ventilation at the bedside, has never been compared to positron-emission tomography (PET), a gold-standard to quantify regional ventilation.

Choosing A Ventilator Care Program

Tue, 2 Jun 2009 10:47:07 -0400

When choosing a program for a loved one's recovery you will have to do some research, ask questions of the programs staff, ask for statistics and make sure you visit the program.

Lung injury after hemorrhage is age dependent: Role of peroxisome proliferator-activated receptor [gamma]

Tue, 2 Jun 2009 10:47:07 -0400

Critical Care Medicine. 37(6):1978-1987, June 2009

The incidence of multiple organ failure in pediatric trauma victims is lower than in the adult population.

Basic Principles and Postprocessing Techniques of Dual-Energy CT: Illustrated by Selected Congenital Abnormalities of the Thorax

Tue, 2 Jun 2009 10:46:22 -0400

Journal of Thoracic Imaging: May 2009 - Volume 24 - Issue 2 - pp 152-159

Recent technologic advances in multidetector computed tomography have allowed the performance of simultaneous acquisition dual-energy computed tomography (DECT).

Cardiac causes of pulmonary arterial hypertension: assessment with multidetector CT

Tue, 2 Jun 2009 10:45:24 -0400

European Radiology 0938-7994 (Print) 10.1007/s00330-009-1460-0

The causes of pulmonary arterial hypertension (PAH) are diverse and include multiple congenital and acquired cardiac diseases as well as diseases primarily affecting the pulmonary vasculature, lung, pleura and chest wall.

Gender differences in the association of overweight and asthma morbidity among urban adolescents with asthma

Tue, 2 Jun 2009 10:44:34 -0400

Pediatric Allergy and Immunology, Volume 20, Number 4, June 2009 , pp. 362-369(8)

Asthma and obesity disproportionately affect US African-American youth. Among youth with asthma, obesity has been associated with poor control. The impact of gender on this association is unclear.

Sleep Apnea: Traffic and Occupational Accidents - Individual Risks, Socioeconomic and Legal Implications

Tue, 2 Jun 2009 10:43:40 -0400

Respiration (DOI: 10.1159/000222811)

Obstructive sleep apnea has been associated with a high risk for motor vehicle accidents, probably the highest of all risks due to medical conditions.

The impact of prescription charges on asthma patients is uneven and unpredictable: evidence from qualitative interviews

Tue, 2 Jun 2009 10:39:53 -0400

Primary Care Respiratory Journal Received 16 May 2008 Accepted 22 December 2008 Online 30 May 2009

To explore whether, and how, prescription charges affect asthma patients’ disease management behaviour.

A Randomized Trial of Dental Brushing for Preventing Ventilator-Associated Pneumonia

Tue, 2 Jun 2009 10:38:47 -0400

Chest Published online before print May 2009, doi: 10.1378/chest.09-0706

Poor oral hygiene is associated with respiratory pathogen colonization and secondary lung infection. The impact of adding electric toothbrushing to oral care in order to reduce VAP incidence is unknown.

Three years of pulmonary rehabilitation: inhibit the decline in airflow obstruction, improve exercise endurance time, and body-mass index, in chronic obstructive pulmonary disease

Tue, 2 Jun 2009 10:37:57 -0400

BMC Pulmonary Medicine 2009, 9:26doi:10.1186/1471-2466-9-26

Pulmonary rehabilitation is known to be a beneficial treatment for COPD patients. To date, however, there is no agreement for how long a rehabilitation program should be implemented.

Find Out When the Next Respiratory Conference is

Tue, 2 Jun 2009 10:36:43 -0400

Find out when the next conference is or plan out your conference schedule for the year.

Check back often this resources is constantly being updated with new listings added throughout the year.

Exacerbation rate, health status and mortality in COPD - a review of potential interventions

Tue, 2 Jun 2009 10:36:43 -0400

International Journal of COPD Published: May 2009

COPD is prevalent in Western society and its incidence is rising in the developing world. Acute exacerbations of COPD, about 50% of which are unreported, lead to deterioration in quality of life and contribute significantly to disease burden.

Insulin Receptor Substrate-1/2 Mediates IL-4-Induced Migration of Human Air-way Epithelial Cells

Tue, 2 Jun 2009 10:35:52 -0400

Am J Physiol Lung Cell Mol Physiol (May 15, 2009). doi:10.1152/ajplung.90453.2008

Migration of airway epithelial cells (AEC) is an integral component of airway mucosal repair after injury.

Th2-driven Inflammation Defines Major Sub-phenotypes of Asthma

Tue, 2 Jun 2009 10:35:11 -0400

Am. J. Respir. Crit. Care Med. 2009, doi:10.1164/rccm.200903-0392OC

T-helper type 2 (Th2) inflammation, mediated by IL-4, IL-5 and IL-13, is considered the central molecular mechanism underlying asthma, and Th2 cytokines are emerging therapeutic targets.

Stem cell factor and its soluble receptor (c-kit) in serum of asthmatic patients- correlation with disease severity

Tue, 2 Jun 2009 10:34:14 -0400

BMC Pulmonary Medicine 2009, 9:27doi:10.1186/1471-2466-9-27

SCF (stem cell factor) is a pleiotropic cytokine exerting its role at different stages of bone marrow development and affecting eosinophil activation, mast cells and basophil chemotaxis and survival.

Rehabilitation - Recovery - Reentry

Tue, 2 Jun 2009 10:33:16 -0400

Northeast Center for Special Care is well known for its outcomes, with nearly a decade of assisting individuals to wean from ventilators and return to their communities.

Visit us and learn more.

The effect of increasing doses of norepinephrine on tissue oxygenation and microvascular flow in patients with septic shock

Tue, 2 Jun 2009 10:33:16 -0400

Critical Care Medicine. 37(6):1961-1966, June 2009

To investigate the effect of escalating doses of norepinephrine, aimed at achieving incremental increases in mean arterial pressure (MAP), on microvascular flow and tissue oxygenation in patients with septic shock.

DNA damage in children with asthma bronchiale and its association with oxidative and antioxidative measurements

Tue, 2 Jun 2009 10:32:02 -0400

Pediatric Allergy and Immunology, Volume 20, Number 4, June 2009 , pp. 370-376(7)

Increased production of reactive oxygen species leading to an imbalance between the oxidative forces and the antioxidant defense systems favoring an oxidative injury has been implicated in the pathogenesis of asthma.

Bosentan as a bridge to pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension

Tue, 2 Jun 2009 10:30:38 -0400

The Journal of Thoracic and Cardiovascular Surgery Received 20 October 2008; received in revised form 23 March 2009; accepted 29 March 2009. published online 01 June 2009

In proximal chronic thromboembolic pulmonary hypertension, pulmonary endarterectomy is the treatment of first choice. In general, medical treatment before pulmonary endarterectomy is not indicated.

Protection from LPS-Induced Lung Injury by Augmentation of Airway S-Nitrosothiols

Tue, 2 Jun 2009 10:29:20 -0400

American Journal of Respiratory and Critical Care Medicine Published ahead of print on March 26, 2009, doi:10.1164/rccm.200807-1186OC

S-nitrosothiols (SNO) inhibit immune activation of the respiratory epithelium and airway SNO levels are decreased in inflammatory lung disease.

The potential of Mycobacterium to protect against allergy and asthma

Tue, 2 Jun 2009 10:28:10 -0400

Current Allergy and Asthma Reports Volume 7, Number 3 / July, 2007 223-230

The increase in the global incidence of atopic disease and asthma during the past few decades has been ascribed to environmental factors, including the reduction in exposure to serious infections.

FAD Group - Adaptive Devices for Artists with Disabilities

Tue, 2 Jun 2009 10:26:54 -0400

The FAD Group at Northeast Center for Special Care - FAD stands for: Fabricators of Adaptive Devices, and those fabricators are Resident-Neighbors who participate in the brain injury and spinal cord injury rehabilitation programs at Northeast Center.

The members of the FAD Group formed the group as volunteers in order to perform a special service - designing and constructing adaptive devices, in conjunction with the rehabilitation department, to enable other Resident-Neighbors to work more freely in the Art Studio program at the Center.

Overlap syndrome: an indication for sleep studies?

Tue, 2 Jun 2009 10:26:54 -0400

Sleep and Breathing 1520-9512 (Print) 10.1007/s11325-009-0263-5

The coexistence of obstructive sleep apnea (OSA) and chronic obstructive pulmonary diseases (COPD) is known as overlap syndrome (OS); it occurs in 10-20% of patients with OSA.

Preoperative Assessment of Thymoma: Evaluation of Mediastinal Arterial Anatomy by Cardiac Multidetector Computed Tomography

Tue, 2 Jun 2009 10:25:54 -0400

Journal of Thoracic Imaging: February 2009 - Volume 24 - Issue 1 - pp 31-33

We describe the clinical case of a thymoma, surgically removed after diagnosis, staging, and preoperative assessment performed by means of cardiac electrocardiogram-gated multidetector computed tomography.

Adherence and persistence with omalizumab and fluticasone/salmeterol within a managed care population

Tue, 2 Jun 2009 10:25:03 -0400

Allergy and Asthma Proceedings, Volume 30, Number 2, March/April 2009 , pp. 148-157(10)

Asthma control requires adherence with pharmacologic therapy. A medication's mode of delivery may affect adherence.

Computed Tomographic Pulmonary Angiography in the Assessment of Severity of Acute Pulmonary Embolism and Right Ventricular Dysfunction

Tue, 2 Jun 2009 10:24:11 -0400

Acta Radiologica First Published on: 01 June 2009

The distinction between severe pulmonary embolism (PE) and right heart dysfunction is important for predicting patient mortality.

Imaging of Cardiac Herniation in Traumatic Pericardial Rupture

Tue, 2 Jun 2009 10:22:51 -0400

Journal of Thoracic Imaging: February 2009 - Volume 24 - Issue 1 - pp 69-72

Cardiac herniation as a result of traumatic pericardial rupture is a serious injury and a difficult diagnosis to make on radiographic studies.

Molecular diagnosis of Pneumocystis jiroveci pneumonia in immunocompromised patients

Tue, 2 Jun 2009 10:21:57 -0400

Mycoses Published Online: 1 Jun 2009

Pneumocystis jiroveci is the major cause of pneumonia in immunocompromised patients.

OUTCOMES - The Northeast Center for Special Care online newsletter

Tue, 2 Jun 2009 10:20:59 -0400

Subscribe for FREE and receive our regular mailings with information about brain injury, spinal cord injury, respiratory care, and more.

Moraxella catarrhalis, a Human Respiratory Tract Pathogen

Tue, 2 Jun 2009 10:20:59 -0400

Clinical Infectious Diseases 2009;49:000-000

Moraxella catarrhalis is an exclusively human pathogen and is a common cause of otitis media in infants and children, causing 15%-20% of acute otitis media episodes.

Clinical Outcomes of Video-Assisted Thoracoscopic Lobectomy

Tue, 2 Jun 2009 10:20:13 -0400

Mayo Clinic Proceedings June 2009 vol. 84 no. 6 509-513

To review our experience with video-assisted thoracoscopic (VATS) lobectomy with respect to morbidity, mortality, and short-term outcome.

Predictors of Extensively Drug-Resistant Pulmonary Tuberculosis

Tue, 2 Jun 2009 10:18:48 -0400

Annals of Internal Medicine 2 June 2009 Volume 150 Issue 11 Pages 766-775

About 40 000 cases of extensively drug-resistant tuberculosis emerge worldwide annually, but the predictors of extensive drug resistance are unclear.

Distal Airway Function Assessed by Oscillometry at Varying Respiratory Rate: Comparison with Dynamic Compliance

Tue, 2 Jun 2009 10:17:48 -0400

COPD: Journal of Chronic Obstructive Pulmonary Disease, Volume 6, Issue 3 June 2009 , pages 162 - 170

Distal airways disease causes significant morbidity yet remains insufficiently identified.

Activities of Life: The COPD Patient

Tue, 2 Jun 2009 10:17:01 -0400

COPD: Journal of Chronic Obstructive Pulmonary Disease, Volume 6, Issue 3 June 2009 , pages 192 - 200

Chronic obstructive pulmonary disease (COPD) is a chronic, progressive and debilitating disease. With worsening disease, a COPD patient will progressively become less physically active, will have reduced social contacts, and this will create a downward vicious circle.

Biomarkers in the management of COPD

Tue, 2 Jun 2009 10:16:04 -0400

EUROPEAN RESPIRATORY REVIEW, 2009;18: 96-104

Chronic obstructive pulmonary disease (COPD) is still a leading cause of morbidity and mortality worldwide, with a huge socioeconomic impact.

Urban Minority Children with Asthma: Substantial Morbidity, Compromised Quality and Access to Specialists, and the Importance of Poverty and Specialty Care

Tue, 2 Jun 2009 10:15:19 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 392 - 398

Asthma disproportionately affects minorities, but not enough is known about morbidity and specialist access in asthmatic minority children.

The FEF25-75 and its Decline as a Predictor of Methacholine Responsiveness in Children

Tue, 2 Jun 2009 10:14:38 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 375 - 381

Methacholine challenge (MCC) is an important diagnostic tool for asthma, especially in patients in whom routine pulmonary function testing (PFT) is normal or equivocal.

The Efficacy of Montelukast during the Allergy Season in Pediatric Patients with Persistent Asthma and Seasonal Aeroallergen Sensitivity

Tue, 2 Jun 2009 10:13:40 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 413 - 420

To determine the effect of montelukast on asthma during the allergy season in children with persistent asthma and seasonal aeroallergen sensitivity.

THE LATEST NEWS

Tue, 2 Jun 2009 10:13:00 -0400

Brain injury, rehabilitation, spinal cord injury, respiratory, healthcare, disabilities and more........

Northeast Center News Feed delivers the breaking headlines and current stories right to your computer via RSS.

Subscribe for FREE

The Anti-inflammatory Effects of Inhaled Corticosteroids versus Anti-leukotrienes on the Lymphocyte P-Glycoprotein (PGP) Expression in Asthmatic Children

Tue, 2 Jun 2009 10:13:00 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 366 - 370

Inhaled corticosteroids (ICS) are used in asthma therapy for their anti-inflammatory effects. P-glycoprotein (PGP) is a transmembrane efflux pump for many drugs, including corticosteroids. Expression of PGP is associated with therapy resistant disease.

The Ala Allele at Val762Ala Polymorphism in Poly(ADP-ribose) Polymerase-1 (PARP-1) Gene is Associated with a Decreased Risk of Asthma in a Turkish Population

Tue, 2 Jun 2009 10:12:17 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 371 - 374

It has been suggested that inhibition of poly (ADP-ribose) polymerase-1 (PARP-1), either pharmacologically or by a gene knockout provides significant protection against systemic or tissue inflammation in animal models.

Reversal of Bronchial Obstruction with Bi-level Positive Airway Pressure and Nebulization in Patients with Acute Asthma

Tue, 2 Jun 2009 10:11:33 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 356 - 361

Jet nebulization (JN) and non-invasive mechanical ventilation (NIMV) through bi-level pressure is commonly used in emergency and intensive care of patients experiencing an acute exacerbation of asthma.

Prevalence of Asthma, Allergic Rhinitis and Eczema among Lebanese Adolescents

Tue, 2 Jun 2009 10:10:48 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 382 - 387

Studies on allergic diseases remain scarce in Lebanon. The aim of the present study was to determine prevalence and characteristics of asthma, allergic rhinitis and eczema among Lebanese school children.

Prevalence of Asthma Symptoms and Atopic Disorders in Preschool Children and the Trend over a Decade

Tue, 2 Jun 2009 10:10:02 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 343 - 346

Over the last few decades, there have been substantial publications on the prevalence and trends of asthma in school-age children and adolescents.

Nocturnal Reflux in Children and Adolescents with Persistent Asthma and Gastroesophageal Reflux

Tue, 2 Jun 2009 10:09:18 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 347 - 350

A higher frequency of nocturnal gastroesophageal reflux (GER) in adult patients with respiratory symptoms has been demonstrated.

Mechanisms of Sublingual Immunotherapy

Tue, 2 Jun 2009 10:08:37 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 322 - 334

Allergen-specific sublingual immunotherapy is now recognized to be an efficacious and well-tolerated treatment for allergic rhinitis.

High Prevalence of Depression amongst Mothers of Children with Asthma

Tue, 2 Jun 2009 10:07:50 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 388 - 391

To compare the prevalence of depression among mothers of children with asthma and mothers of children without asthma and to investigate the influence of severity and duration of childhood asthma on maternal depression.

Esophageal Candidiasis-An Adverse Effect of Inhaled Corticosteroids Therapy

Tue, 2 Jun 2009 10:07:08 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 399 - 401

Over the last few decades, inhaled corticosteroids (ICs) became the cornerstone in the treatment of persistent asthma.

Podcast - Neuro-Optometry and Traumatic Brain Injury NEW FOR MAY!

Tue, 2 Jun 2009 10:06:21 -0400

Host: Gerry Brooks, MA, CCC, CBIST

Guest: Neera Kapoor, O.D., M.S., FAAO, B.Sc, Associate Clinical Professor and Director of the Raymond J. Greenwald Rehabilitation Center, SUNY- Optometry, New York.

Time: 28:56

Synopsis: Vision is one of our most important senses and it is vulnerable to impairment after a traumatic brain injury. In this program our Guest Dr. Neera Kapoor who gives an overview of Neuro-Optometry and discusses why if differs from Ophthalmology and Optometry and the role Neuro-Optometric rehabilitation provides in assessing and treating vision problems after a traumatic brain injury. Dr. Kapoor also gives listeners useful criteria for finding a Neuro-Optometrist, how is an examination done and the most common treatments.

Efficacy of Itraconazole in the Treatment of Patients with Chronic Cough Whose Sputa Yield Basidiomycetous Fungi-Fungus-Associated Chronic Cough (FACC)

Tue, 2 Jun 2009 10:06:21 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 407 - 412

This controlled study was performed to clarify the therapeutic benefit of itraconazole for the treatment of patients with chronic cough, wherein a sputum culture yielded basidiomycetous (BM) fungi.

Deaths with Asthma in France, 2000-2005: A Multiple-Cause Analysis

Tue, 2 Jun 2009 10:05:39 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 402 - 406

Mortality from asthma has decreased in many countries since the 1990s. Mortality statistics are usually based only on the underlying cause of death.

Asthma-Like Symptoms are Increased in the Metabolic Syndrome

Tue, 2 Jun 2009 10:04:58 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 339 - 342

The prevalence of obesity and asthma has been increasing during the last several decades. Obesity has been reported to be associated with asthma. Obesity, especially abdominal obesity, is the main component of the metabolic syndrome.

Asthma and Asthma Severity among African American Adults in the Jackson Heart Study

Tue, 2 Jun 2009 10:04:17 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 421 - 428

The aims of this study were to investigate the baseline prevalence of and risk factors associated with asthma, classify asthma severity, and describe medication use in a population-based sample of African American men and women 21 to 84 years of age from the Jackson Heart Study (JHS).

Association Between Asthma Symptoms and Obesity in Preschool (4-5 year old) Children

Tue, 2 Jun 2009 10:03:41 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 362 - 365

There have been many publications looking at the association between asthma and obesity in school aged children and adolescents.

Angiotensin Converting Enzyme Gene Polymorphism in Turkish Asthmatic Patients

Tue, 2 Jun 2009 10:03:01 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 335 - 338

Asthma is a chronic inflammatory disease of the airways. Several candidate genes have been identified with a potential role in the pathogenesis of asthma, including the angiotensin converting enzyme (ACE) gene.

An Evaluation of the Use of Bronchoconstriction Induced by Deep Inspiration as a New Epidemiological Measure for Asthma

Tue, 2 Jun 2009 10:02:04 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 319 - 321

Bronchoconstriction after deep inhalation is associated with increased severity of asthma and is also a predictor of length of hospital stay in individuals admitted with asthma exacerbations.

A MCh Test Pre-post Esophageal Acidification in Detecting GER-related Asthma

Tue, 2 Jun 2009 10:01:09 -0400

Journal of Asthma, Volume 46, Issue 4 May 2009 , pages 351 - 355

The direct effect of gastro-esophageal reflux (GER) on lung function is still debated. Objective. To investigate the role of esophageal acidification in affecting airway response to MCh in GER-related versus atopic asthmatics and to assess specificity and sensitivity of events.

Long-term activation of TLR3 by Poly(I:C) induces inflammation and impairs lung function in mice

Tue, 2 Jun 2009 10:00:24 -0400

Respiratory Research 2009, 10:43doi:10.1186/1465-9921-10-43

The immune mechanisms associated with infection-induced disease exacerbations in asthma and COPD are not fully understood. Toll-like receptor (TLR) 3 has an important role in recognition of double-stranded viral RNA, which leads to the production of various inflammatory mediators.

Cyclic hydrostatic pressure and cotton particles stimulate synthesis by human lung macrophages of cytokines in vitro

Tue, 2 Jun 2009 09:59:28 -0400

Respiratory Research 2009, 10:44doi:10.1186/1465-9921-10-44

Inhalation of particulates is a leading cause of the development of lung diseases and current understanding of the complex relationship between lung metabolism and airborne particulates is incomplete.

The feasibility of using auto-titrating continuous positive airway pressure to treat obstructive sleep apnoea after acute tetraplegia

Tue, 2 Jun 2009 07:46:05 -0400

Spinal Cord advance online publication 2 June 2009; doi: 10.1038/sc.2009.56

Obstructive sleep apnoea (OSA) is common within weeks of tetraplegia.