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The Angle Orthodontist: Vol. 76, No. 6, pp. 962-969.
To evaluate dentofacial characteristics in relation to obesity and degree of severity of obstructive sleep apnea (OSA) in male Chinese patients and to elucidate the relationship between demographic parameters (age, body weight, height, and body mass index [BMI]) cephalometric parameters and OSA in these subjects.
American Journal of Transplantation, Volume 6, Number 10, October 2006, pp. 2436-2442(7)
We previously reported poorer survival among non-Hispanic blacks and Hispanics with idiopathic pulmonary fibrosis (IPF) compared to non-Hispanic whites at our center.
Respiratory Medicine Volume 100, Issue 10 , October 2006, Pages 1760-1766
Assessment of the bronchodilation response to short-acting β2-adrenoreceptor agonists on pharmacologically induced bronchoconstriction has often been used to investigate airway smooth muscle B2-adrenoreceptor function.
Current guidelines generally recommend a combination of inhaled corticosteroids and a Beta(2)-agonist for persistent asthma. The adjustment of anti-inflammatory therapy in persistent asthma is advised to be guided mainly by the presence of symptoms.
Annals of Allergy, Asthma and Immunology, Volume 97, Number 3, September 2006, pp. 389-396(8)
To evaluate the effects of cetirizine hydrochloride (5 mg)-pseudoephedrine hydrochloride (120 mg) (cetirizine-D) twice daily on AR and asthma symptoms, pulmonary function, and asthma-related quality of life in 274 patients with confirmed seasonal AR and concomitant mild-to-moderate asthma.
Allergy, Volume 61, Number 11, November 2006, pp. 1351-1357(7)
Allergic asthma has been linked to an increase in T-helper type 2-like cytokines and T cells, but there is growing evidence for a role of lymphocyte-mediated cytotoxic mechanisms in the pathogenesis of asthma.
Respiratory Medicine Volume 100, Issue 10 , October 2006, Pages 1807-1816
Many chronic obstructive pulmonary disease (COPD) patients are dissatisfied with the information they are given. A brief questionnaire completed prior to the clinical encounter would assist health professionals identify areas of information need.
Pediatric Infectious Disease Journal. 25(9):804-808, September 2006
The aim of the study was to evaluate the prevalence of torquetenovirus (TTV) infection in a group of children with recurrent lower respiratory tract infections and radiologic evidence of bronchiectasis. Correlations between TTV loads and severity of bronchiectasis and between TTV loads and lung function were evaluated.
Canadian Respiratory Journal September 2006, Volume 13, Number 6 : 317-324
To determine factors associated with the length of stay (LOS) for patients with suspected community-acquired pneumonia (CAP) who required hospitalization for treatment.
Respiratory Medicine Volume 100, Issue 10 , October 2006, Pages 1826-1833
Doppler ultrasound of extracranial internal carotid artery (ICA) and vertebral artery (VA) were performed and total cerebral blood flow volume (tCBFV) was evaluated in chronic obstructive pulmonary disease (COPD) patients. CBFV changes due to blood gas changes were also evaluated.
Respiratory Medicine Volume 100, Issue 10 , October 2006, Pages 1800-1806
The present study evaluated the relationship between health status (HS) and peripheral muscle histochemical characteristics in chronic obstructive pulmonary disease (COPD), and identified selected independent respiratory and extrapulmonary variables that predicted the HS of these patients.
Respiratory Medicine Volume 100, Issue 10 , October 2006, Pages 1817-1825
The aim of the study was to determine whether 16 sessions of exercise training, completed twice weekly, alters exercise capacity, quadriceps muscle metabolism, cross-sectional area (CSA) and strength in subjects with chronic obstructive pulmonary disease (COPD).
Pediatric Infectious Disease Journal. 25(9):795-800, September 2006
We sought to estimate the incidence of hospitalization attributable to influenza virus infection in Canadian children while controlling for the impact of other respiratory viruses.
Respiratory Medicine Volume 100, Issue 10 , October 2006, Pages 1791-1799
Chronic inflammation of the airways is a hallmark of chronic obstructive pulmonary disease (COPD). We investigated the kinetics of priming of inflammatory cells in peripheral blood during exacerbations of COPD and during the resolution phase.
Journal of Allergy and Clinical Immunology Volume 118, Issue 3 , September 2006, Pages 622-626
Recent studies suggest that TH1/TH2 and TC1/TC2 cell imbalances are implicated in asthma pathogenesis. However, the relationship of T-cell profiles to airway inflammation has not been understood.
Respiratory Medicine Volume 100, Issue 10 , October 2006, Pages 1671-1681
Oral vaccines using killed bacterial extracts have been used to prevent acute exacerbations of chronic obstructive pulmonary disease (COPD); however, they are not recommended by current clinical guidelines.
Surgery for pulmonary aspergilloma is reputed to be risky. The results of surgical treatment of pulmonary aspergilloma in 41 patients between 1988 and 2003 were evaluated retrospectively.
Sleep Medicine Volume 7, Issue 6 , September 2006, Pages 521-528
We postulate that the prevalence of sleep-disordered breathing (SDB) in subjects admitted with acute coronary syndrome (ACS) is high, self-report of SDB symptoms is helpful in identifying patients with ACS at risk for SDB, and prospective risk for adverse ACS outcomes is associated with SDB.
Current Opinion in Pediatrics. 18(5):539-544, October 2006
Family processes are best conceptualized within an integrated, dynamic biopsychosocial model of pediatric asthma. We reviewed the literature on specific family processes proposed to influence asthma outcomes, the mechanisms of influence, and family-focused interventions to improve asthma control.
Journal of Allergy and Clinical Immunology Volume 118, Issue 3 , September 2006, Pages 591-596
Human rhinoviruses (HRVs) are a common cause of upper respiratory tract infections. There is growing evidence that HRVs are also important in lower respiratory tract infections and often induce asthma exacerbations.
In case of an influenza pandemic, the world will be in a situation where potential vaccine supply will fall short by several billion doses from global needs.
Considerable interest exists in the potential therapeutic value of dietary supplementation with the omega-3 fatty acids. Given the interplay between pro-inflammatory omega-6 fatty acids, and the less pro-inflammatory omega-3 fatty acids, it has been thought that the latter could play a key role in treating or preventing asthma.
European Journal of Radiology Volume 59, Issue 2 , August 2006, Pages 238-243
Based on the hypothesis that airway remodelling is related to the duration of asthma, HRCT scanning should show greater abnormalities in the early-onset than the late-onset asthmatics.
Respiratory Medicine Volume 100, Issue 10 , October 2006, Pages 1767-1774
The aim of our study was to assess the prevalence of anxiety and depression in the whole chronic obstructive pulmonary disease (COPD) population and in subgroups according to sex and severity classification.
Respiratory Medicine Volume 100, Issue 10 , October 2006, Pages 1682-1687
Pulmonary embolism (PE) is the commonest cause of maternal death in UK. It is a frequently occurring diagnostic challenge. The false negative and false positive rates for the diagnosis of PE are spectacularly high.
Chronic Respiratory Disease, Volume 3, Number 3, August 2006, pp. 123-131(9)
Health professionals recommend education of patients about COPD. There is no satisfactory instrument to measure their knowledge and therefore to assess the results of education. A multiple-choice questionnaire (BCKQ) has been designed and tested.
Annals of Allergy, Asthma and Immunology, Volume 97, Number 3, September 2006, pp. 298-305(8)
To discuss the Health Plan Employer Data and Information Set (HEDIS) criteria for measuring performance in asthma care and to review new strategies to improve the quality of asthma care.
Chronic obstructive pulmonary disease (COPD) is associated with increased apoptosis and defective phagocytosis in the airway. As uncleared cells can undergo secondary necrosis and perpetuate inflammation, strategies to improve clearance would have therapeutic significance.
A mild-to-moderate increase in pulmonary arterial pressure is often associated with severe chronic obstructive pulmonary disease (COPD). Transforming growth factor (TGF)-B is a cytokine involved in the maintenance of integrity of vasculature. The aim of the study was to investigate whether the TGF-B pathway might be involved in the development of pulmonary hypertension associated with COPD.
Previous studies have shown that microsatellite (MS) DNA instability (MSI) is detectable in sputum cells in chronic obstructive pulmonary disease (COPD) and asthma. The aim of the present study was to investigate whether asthma and COPD could be distinguished at the MS DNA level.
Reticular basement membrane (RBM) thickening in asthma is considered to be the result of subepithelial fibrosis. Thus, the RBM in asthma should contain an excess of fibrils identified as interstitial collagen and the ratio of fibril to matrix should be increased above normal levels.
Annals of Allergy, Asthma and Immunology, Volume 97, Number 3, September 2006, pp. 288-293(6)
To report the efficacy of omalizumab in 2 obese pediatric patients with severe persistent asthma whose high body weights placed them outside current dosing guidelines.
Sleep Medicine Volume 7, Issue 6 , September 2006, Pages 498-507
Obstructive sleep apnea–hypopnea (OSAH) is associated with sleep fragmentation and nocturnal hypoxemia. In clinical samples, patients with OSAH frequently are found to have deficits in neuropsychological function. However, the nature and severity of these abnormalities in non-clinical populations is less well defined.
Chronic Respiratory Disease, Volume 3, Number 3, August 2006, pp. 149-159(11)
Pulmonary alveolar proteinosis is a rare syndrome characterized by intra-alveolar accumulation of surfactant components and cellular debris, with minimal interstitial inflammation or fibrosis. The condition has a variable clinical course, from spontaneous resolution to respiratory failure and death due to disease progression or superimposed infections.
Chronic Respiratory Disease, Volume 3, Number 3, August 2006, pp. 141-148(8)
Chronic obstructive pulmonary disease (COPD) limits the ability to perform activities of daily living (ADL). The Pulmonary Functional Status and Dyspnoea Questionnaire (PFSDQ) measures general dyspnoea, dyspnoea during ADL (dyspnoea score) and loss of functional performance (activity score) for a large number of activities commonly performed by adults.
Annals of Allergy, Asthma and Immunology, Volume 97, Number 3, September 2006, pp. 397-401(5)
To evaluate whether a combination of oral montelukast and 200 ug of inhaled budesonide has comparable efficacy to 400 ug of inhaled budesonide alone in children with moderate persistent asthma.
American Journal of Respiratory and Critical Care Medicine Vol 174. pp. 524-529, (2006)
Chronic obstructive pulmonary disease (COPD) is a leading cause of death worldwide. The prevalence of COPD is rising among women and is approaching that of men, but it is not known if sex affects survival.
Journal of Critical Care Volume 21, Issue 2 , June 2006, Pages 185-190
Few studies have focused on extubation outcome in patients with chronic obstructive pulmonary disease (COPD) requiring mechanical ventilation (MV). We conducted a study using prospectively collected data in a cohort of patients with COPD requiring invasive MV to identify variables associated with extubation failure.
Journal of Hypertension. 24(10):2091-2099, October 2006
Effective treatment of obstructive sleep apnoea (OSA) with nasal continuous positive airway pressure (nCPAP) lowers blood pressure (BP). The long-term effects of nCPAP treatment on BP in OSA patients are not well known. The time period of such treatment sufficient to lower BP in OSA patients is also not known. We investigated compliance with long-term nCPAP therapy and its effects on BP.
To investigate the use of high resolution computed tomography (HRCT) in diagnosis of patients with fibrosing alveolitis associated with systemic sclerosis (FA-SSc), and to determine predictors of disease progression.
Annals of Allergy, Asthma and Immunology, Volume 97, Number 3, September 2006, pp. 409-417(9)
Asthma guidelines recommend environmental control practices (ECPs) to improve asthma health. In the inner city, where asthma morbidity is high, it is not known whether children's health status affects the use of ECPs.
Southern Medical Journal. 99(9):1003-1004, September 2006
The case of a patient who developed pulmonary infarction after a vascular stent migrated to her pulmonary artery is presented. Stent migration is a known complication of vascular stents.
PEDIATRICS Vol. 118 No. 3 September 2006, pp. 1056-1064
Nitric oxide mediates and modulates pulmonary transition from fetal to postnatal life. NO is synthesized by 3 nitric oxide synthase isoforms. One key pathway of nitric oxide metabolism results in nitrotyrosine, a stable, measurable marker of nitric oxide production.
Treatments in Respiratory Medicine, Volume 5, Number 4, 2006, pp. 235-244(10)
bstructive sleep apnea (OSA) syndrome is a common and often life-altering sleep-related breathing disorder. It not only adversely affects cardiovascular health, but the quality of life of these patients is also often significantly compromised.
Am J Physiol Lung Cell Mol Physiol 291: L547-L558, 2006
Pulmonary hypertension (PH), defined as a mean pulmonary arterial (PA) pressure of >25 mmHg at rest or >30 mmHg during exercise, is characterized by a progressive and sustained increase in pulmonary vascular resistance that eventually leads to right ventricular failure.
Treatments in Respiratory Medicine, Volume 5, Number 5, 2006, pp. 305-315(11)
The dry-powder inhaler (DPI) Turbuhaler® has been on the market for nearly two decades. Products containing
terbutaline, formoterol, budesonide, and the combination
budesonide/formoterol are widely used by patients with asthma and
COPD.
Treatments in Respiratory Medicine, Volume 5, Number 5, 2006, pp. 317-324(8)
Recurrent respiratory tract infections (RRTIs) in adults are the result of an imbalance between lung defense mechanisms, and bacterial burden. Antibacterial treatments can temporarily restore the equilibrium between host and bacterial load, but do not prevent recurrence of infection.
Treatments in Respiratory Medicine, Volume 5, Number 5, 2006, pp. 343-349(7)
Treatment of chronic obstructive pulmonary disease (COPD) in the emergency department (ED) or hospital accounts for a significant portion of COPD costs. This study estimates the cost of a COPD ED or hospitalization visit in the US.
American Heart Journal Volume 152, Issue 3 , September 2006, Pages 521-526
Reports have linked anorexigen intake to an increased risk of pulmonary arterial hypertension (PAH). With the rise in anorexigen use in the latter half of the last decade, we established a surveillance network within the United States to monitor temporal trends in the number of reported cases of PAH. We also studied whether use of anorexigens and other drugs differed among patients with pulmonary hypertension of different etiologies.
Progress in Pediatric Cardiology Volume 22, Issue 2 , September 2006, Pages 211-223
MR is a powerful tool for evaluation of the pulmonary circulation. With contrast-enhanced three-dimensional angiography and phase-contrast velocity mapping technique, MR provides not only the anatomical detail of the pulmonary vessels but also the hemodynamic information regarding blood flow velocity, volume, distribution and pattern.
Sildenafil prolongs the action of cyclic guanosine monophosphate and nitric oxide by inhibiting cyclic guanosine monophosphate–specific phosphodiesterase 5. It is largely used for erectile dysfunction, a highly prevalent condition in obstructive sleep apnea.
Treatments in Respiratory Medicine, Volume 5, Number 4, 2006, pp. 225-234(10)
Sublingual immunotherapy (SLIT) was proposed for clinical practice about 20 years ago with the main aim of improving the safety and avoiding the adverse effects of traditional treatment for allergic airways disease.
Treatments in Respiratory Medicine, Volume 5, Number 4, 2006, pp. 283-293(11)
Many patients with COPD are misdiagnosed or under-treated. The characteristics of COPD patients and the patterns of treatment have not been well characterized in primary care settings. The objective of this study was to identify patterns of COPD onset, diagnosis and treatment with the goal of facilitating appropriate treatment at earlier stages.
Treatments in Respiratory Medicine, Volume 5, Number 4, 2006, pp. 255-269(15)
There is an increasing number of viral and bacterial pathogens suspected of contributing to asthma pathogenesis in childhood, making it more difficult for the practitioner to make specific therapy decisions.
Treatments in Respiratory Medicine, Volume 5, Number 4, 2006, pp. 245-253(9)
Inhaled corticosteroids are effective in controlling airway inflammation. Their anti-inflammatory effect is primarily topical, at the site of deposition in the airways. Consequently, traditional pharmacodynamic and pharmacokinetic concepts, which rely on measuring blood concentrations of drug, have limited applicability for evaluating the efficacy of topically acting inhaled corticosteroids.
Treatments in Respiratory Medicine, Volume 5, Number 4, 2006, pp. 271-282(12)
Idiopathic pulmonary arterial hypertension (IPAH) is a rare progressive disorder historically associated with mortality in <3 years post-diagnosis. The etiology of PAH is complex, multifactorial, and likely involves the interplay between genetic and environmental factors.
European Journal of Internal Medicine Volume 17, Issue 6 , October 2006, Pages 402-407
The issue of “hospital at home” (HAH) for acute respiratory patients is one that is still being debated, partly because economic, cultural and health service differences between locations imply that HAH schemes need to be tailored to local situations. The aim of the present study was to analyze the feasibility and effectiveness of HAH for patients with acute respiratory disease at our institution.
American Journal of Respiratory and Critical Care Medicine Vol 174. pp. 810-816, (2006)
Idiopathic pulmonary fibrosis is a chronic interstitial lung disease of unknown etiology; its epidemiology in the United States has not been well characterized.
Am J Physiol Lung Cell Mol Physiol 291: L668-L676, 2006
Severe pulmonary hypertension (SPH) is characterized by precapillary arteriolar lumen obliteration, dramatic right ventricular hypertrophy, and pericardial effusion. Our recently published rat model of SPH recapitulates major components of the human disease.
Posttraumatic pseudoaneurysms of the brachiocephalic artery are relatively rare. We report the case of a 64-year-old man who presented with a large posttraumatic brachiocephalic aneurysm and recurrent pneumonia.
Treatments in Respiratory Medicine, Volume 5, Number 3, 2006, pp. 159-166(8)
Leukocyte infiltration of the lung is a characteristic feature of allergic asthma and it is thought that these cells are selectively recruited by chemokines. Extensive research has confirmed that chemokine receptors are expressed on the main cell types involved in asthma, including eosinophils, T helper type 2 cells, mast cells and even neutrophils.
Respiratory Medicine Volume 100, Issue 10 , October 2006, Pages 1716-1723
To explore the experiences of chronic obstructive pulmonary disease (COPD) patients invited to join a pulmonary rehabilitation (PR) programme. PR has been shown to be an effective non-pharmacological intervention; however uptake and completion of programmes is frequently low.
Respiratory Medicine Volume 100, Issue 10 , October 2006, Pages 1734-1741
The 6-min walk test (6MWT) has prognostic value in various pulmonary disorders including idiopathic pulmonary fibrosis (IPF). We determined the individual prognostic accuracy of distance walked and oxygen saturation during the 6MWT in patients with IPF.
Treatments in Respiratory Medicine, Volume 5, Number 3, 2006, pp. 193-206(14)
In this comprehensive review, two very closely related interstitial pneumonias are discussed: the cryptogenic form of organizing pneumonia (COP); and secondary forms of organizing pneumonia (OP), which occur in association with identifiable medical conditions. Some newer and lesser known of these associated conditions are described, most importantly post-radiation OP.
Treatments in Respiratory Medicine, Volume 5, Number 3, 2006, pp. 207-217(11)
Asthma is a chronic inflammatory condition characterised by reversible airflow obstruction and airway hyperreactivity. The course of the illness may be punctuated by exacerbations resulting in deterioration in quality of life and, in some cases, days lost from school or work.
Treatments in Respiratory Medicine, Volume 5, Number 3, 2006, pp. 149-158(10)
Histamine is an important mediator in airway inflammation. It is elevated in the airways of asthmatic patients and is responsible for many of the pathophysiological features in asthma.
Respiratory Medicine Volume 100, Issue 10 , October 2006, Pages 1742-1752
The present study was performed to clarify the clinical characteristics of chronic obstructive pulmonary disease (COPD) patients classified into phenotypes according to the dominancy of emphysema and the presence of bronchial wall thickening evaluated by chest high-resolution computed tomography (HRCT).
Treatments in Respiratory Medicine, Volume 5, Number 3, 2006, pp. 167-179(13)
Hypersensitivity pneumonitis (HP) represents a group of lung disorders caused by the inhalation of a wide variety of organic particles by susceptible individuals. HP occurs mainly in nonsmokers, but smoking may promote an insidious and chronic disease.
Allergy, Volume 61, Number 10, October 2006, pp. 1202-1208(7)
Quantitative relationships between immunological reactivity, non-specific bronchial responsiveness and bronchial responsiveness to allergens have scarcely been investigated in occupational asthma.
Compared with standard medical therapy (SMT), noninvasive ventilation (NIV) does not reduce the need for reintubation in unselected patients who develop respiratory failure after extubation. The goal of this study was to assess whether early application of NIV, immediately after extubation, is effective in preventing postextubation respiratory failure in an at-risk population.
Immunoprophylaxis with influenza vaccine is the primary method for reducing the effect of influenza on children, and inactivated influenza vaccine has been shown to be safe and effective in children.
Cryptogenic organising pneumonia (COP) has also been called idiopathic bronchiolitis obliterans organising pneumonia. In secondary organising pneumonia (SOP) the causes can be identified or it occurs in a characteristic clinical context.
Outcomes in patients with ARDS/acute lung injury (ALI) may be dependent on the underlying cause. We describe the case mix, clinical behavior, and outcomes of patients with ALI/ARDS resulting from pulmonary causes (ALI/ARDSp) and extrapulmonary causes (ALI/ARDSexp).
The prevalence of COPD is estimated to 4 to 14%. According to the Global Initiative for Chronic Obstructive Lung Disease guidelines, COPD is divided into four stages. Patients with stage IV disease (very severe) have FEV1 < 30% of predicted values and/or respiratory insufficiency.
The natural history of asthma involves relatively stable periods that are often punctuated by significant exacerbations of symptoms. There are many aetiologies that may lead to an increase in asthma severity including respiratory infection (bacterial/viral), allergens, irritants, and occupational exposures.
To evaluate the possible role of low socioeconomic status (SES) as a risk factor for cardiovascular disease (CVD) among obstructive sleep apnea syndrome (OSAS) patients requiring treatment.
Sleep Medicine Volume 7, Issue 6 , September 2006, Pages 474-479
Some patients with obstructive sleep apnea syndrome (OSAS) develop problematic central apneas or Cheyne-Stokes pattern with acute application of continuous positive airway pressure (CPAP), herein called complex sleep apnea syndrome (CompSAS).
Persistent air leak is among the most common complications after pulmonary resection, leading to prolonged hospitalization and increased costs. At present there is not yet a consensus on their treatment.
Distinct risk factors for asthma death have not been identified in developing communities. This study was conducted to distinguish risk factors for severe life threatening asthma (SLTA), a proxy for asthma death, in a developing country.
Patients with respiratory infections often require the use of supplemental oxygen via oxygen masks, which, in the hospital, may become sources of aerosolized infectious pathogens.
In this clinical retrospective study cystotomy and capitonnage were compared in patients with childhood pulmonary hydatid cysts with regard to postoperative period.
Australasian Radiology, Volume 50, Number 5, October 2006, pp. 424-428(5)
This is a retrospective study to determine the accuracy and safety of a negative CT pulmonary angiogram
(CTPA) based on clinical outcome and to determine the usefulness of a negative
D-dimer assay before CTPA. A total of 483 patients with a negative CTPA study were followed up for 3 months, with the aim of detecting episodes of venous thromboembolism and mortality.
American Journal of Respiratory and Critical Care Medicine Vol 174. pp. 706-709, (2006)
Congenital central hypoventilation syndrome (CCHS) is a rare neurocristopathy characterized by absence of automatic control of respiration; decreased sensibility to hypoxia and hypercapnia, mainly during sleep; and autosomal dominant inheritance due to heterozygous polyalanine expansions and frameshift mutations in the PHOX2B gene.
Pediatric and Developmental Pathology Article: pp. 361-373
Congenital cystic adenomatoid malformation (CCAM), intralobar sequestration (ILS), extralobar sequestration (ELS), and lobar emphysema (LE) are well-accepted entities; however, certain findings are common to all, particularly the parenchymal maldevelopment characterizing CCAM.
Pulmonary emphysema, as a feature of chronic obstructive pulmonary disease (COPD), is characterised by destruction of alveolar tissue. The present authors previously demonstrated reduced decorin expression in the peribronchial area of COPD patients, reflecting an altered extracellular matrix (ECM) modulation.
PEDIATRICS Vol. 118 No. 3 September 2006, pp. 1097-1103
Children with asthma spend a large portion of their day in school, and the extent to which public schools are prepared to meet their health needs is an important issue. The objective of this study was to identify asthma policies and practices in rural and urban school settings and to compare them with current National Heart, Lung, and Blood Institute recommendations.
American Journal of Respiratory Cell and Molecular Biology. Vol. 35, pp. 488-495, 2006
Both biochemical and genetic evidence have implicated the genes for TNF- (TNFA) and lymphotoxin- (LTA) in atopic asthma. Here, we report for the first time the association of their genotypes and haplotypes with atopic asthma in Indian populations
American Journal of Respiratory Cell and Molecular Biology. Vol. 35, pp. 503-511, 2006
Eosinophils migrate from the vascular circulation to the inflamed airways during asthma exacerbations. While the mechanism(s) of this process is not known, the expression of urokinase-type plasminogen activator receptor (uPAR) has been found to modulate neutrophil adhesion and migration to inflammatory sites.
American Journal of Respiratory and Critical Care Medicine Vol 174. pp. 633-638, (2006)
To estimate outcomes of patients hospitalized for asthma in the United States and to determine if the risk of death in this population is higher among black patients compared with white patients.
To determine if penicillin-nonsusceptible Streptococcus pneumoniae, among other variables, was significantly associated with greater hospital costs among patients with community-acquired pneumonia (CAP).
The present study aimed to assess the impact of diurnal mouthpiece intermittent positive pressure ventilation (MIPPV) as the extension of the nasal intermittent positive pressure ventilation (NIPPV) in Duchenne muscular dystrophy (DMD).
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